16-16-dimethylprostaglandin-e2 and Cough

A feature of cough variant asthma is a heightened cough response to bronchoconstriction. The mediators of this response are unknown. This study was designed to elucidate the role of lipid mediators in bronchoconstriction-triggered cough response in an experimental animal model. We examined the influence of bronchoconstriction on cell components and mediators including prostaglandin E

Topics: 16,16-Dimethylprostaglandin E2; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cough; Cysteine; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Guinea Pigs; Leukotrienes; Male; Methacholine Chloride; Receptors, Prostaglandin E