16-16-dimethylprostaglandin-e has been researched along with Peptic-Ulcer* in 2 studies
2 trial(s) available for 16-16-dimethylprostaglandin-e and Peptic-Ulcer
Article | Year |
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Effect of topical 16,16-dimethyl prostaglandin E2 on intragastric pH in acutely ill patients.
Topics: Acute Disease; Administration, Topical; Antacids; Cimetidine; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Peptic Ulcer; Prostaglandins E, Synthetic; Stomach; Stress, Physiological | 1982 |
Some problems in modern anti-ulcer drug evaluation: a comparison of four gastric acid suppressors.
Some of the problems involved in the treatment and evaluation of drug therapy in peptic ulceration are discussed. The results of four multi-centre, double-blind, placebo-controlled clinical trials in 520 patients are reviewed. It has been shown that the potent suppressors of gastric acid secretion, histamine H2-blockers ranitidine and cimetidine, and 16,16-dimethyl prostaglandin E2, significantly accelerated the healing of peptic ulcers but that trithiozine had no beneficial effect. Topics: Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Depression, Chemical; Drug Evaluation; Furans; Gastric Acid; Humans; Morpholines; Peptic Ulcer; Prostaglandins E, Synthetic; Ranitidine | 1981 |