Compounds > 15-keto-13-14-dihydroprostaglandin-f2alpha

15-keto-13-14-dihydroprostaglandin-f2alpha and Abortion--Spontaneous

15-keto-13-14-dihydroprostaglandin-f2alpha has been researched along with Abortion--Spontaneous* in 2 studies

Other Studies

2 other study(ies) available for 15-keto-13-14-dihydroprostaglandin-f2alpha and Abortion--Spontaneous

Article	Year
Prostaglandins in the fetal circulation following maternal ingestion of a prostaglandin synthetase inhibitor during mid-pregnancy. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1985, Volume: 23, Issue:6 To assess the possible effect upon the fetus of maternal ingestion of the prostaglandin synthetase inhibitor, mefenamic acid, taken during mid-pregnancy (15-22 weeks) to prevent spontaneous abortion, samples of fetal blood were collected at fetoscopy from 13 treated and 14 untreated control cases. Mefenamic acid levels in the fetus were 32-54% of those in the mothers in the treated group, while prostaglandins E2 (PGE2), 6-oxo-PGF1 alpha and PGFM were all slightly but not significantly lower in those patients given 500 mg mefenamic acid 40-180 min prior to sampling than in untreated controls. Results indicate that the prostaglandin synthetase inhibitor crosses the placenta at this early gestation and may possibly suppress fetal prostaglandin production. Topics: 6-Ketoprostaglandin F1 alpha; Abortion, Spontaneous; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Fetal Blood; Fetoscopy; Humans; Maternal-Fetal Exchange; Mefenamic Acid; Pregnancy; Prostaglandins E; Prostaglandins F; Time Factors	1985
Successful pregnancy in an abortion-prone woman: prostaglandin and hormone levels during implantation, gestation and lactation. Prostaglandins and medicine, 1980, Volume: 4, Issue:3 Serum progesterone, human chorionic gonadotropin, prostaglandin E2, F2 alpha and 13,14-dihydro-15-keto-PGF2 alpha and urinary immunoractive prostaglandins E2 and F2 alpha were measured throughout gestation in a woman who previously had experienced three abortions, an immature birth of a twin and a term single pregnancy. Prostaglandin-mediated symptoms such as uterine sensitivity and contractions, backache, spotting, vomiting and diarrhea were carefully registered and have been correlated with the variations in prostaglandin levels. The effect of therapy with a prostaglandin synthetase inhibitor and a beta-adrenergic drug on prostaglandin levels was also studied. The rise of prostaglandin E2 level observed during implantation is discussed. Topics: Abortion, Spontaneous; Adult; Chorionic Gonadotropin; Corpus Luteum; Dinoprost; Embryo Implantation; Female; Humans; Lactation; Pregnancy; Progesterone; Prostaglandins; Prostaglandins E; Prostaglandins F	1980

Article

Year

Prostaglandins in the fetal circulation following maternal ingestion of a prostaglandin synthetase inhibitor during mid-pregnancy.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1985, Volume: 23, Issue:6

To assess the possible effect upon the fetus of maternal ingestion of the prostaglandin synthetase inhibitor, mefenamic acid, taken during mid-pregnancy (15-22 weeks) to prevent spontaneous abortion, samples of fetal blood were collected at fetoscopy from 13 treated and 14 untreated control cases. Mefenamic acid levels in the fetus were 32-54% of those in the mothers in the treated group, while prostaglandins E2 (PGE2), 6-oxo-PGF1 alpha and PGFM were all slightly but not significantly lower in those patients given 500 mg mefenamic acid 40-180 min prior to sampling than in untreated controls. Results indicate that the prostaglandin synthetase inhibitor crosses the placenta at this early gestation and may possibly suppress fetal prostaglandin production.

Topics: 6-Ketoprostaglandin F1 alpha; Abortion, Spontaneous; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Fetal Blood; Fetoscopy; Humans; Maternal-Fetal Exchange; Mefenamic Acid; Pregnancy; Prostaglandins E; Prostaglandins F; Time Factors

1985

Successful pregnancy in an abortion-prone woman: prostaglandin and hormone levels during implantation, gestation and lactation.

Prostaglandins and medicine, 1980, Volume: 4, Issue:3

Serum progesterone, human chorionic gonadotropin, prostaglandin E2, F2 alpha and 13,14-dihydro-15-keto-PGF2 alpha and urinary immunoractive prostaglandins E2 and F2 alpha were measured throughout gestation in a woman who previously had experienced three abortions, an immature birth of a twin and a term single pregnancy. Prostaglandin-mediated symptoms such as uterine sensitivity and contractions, backache, spotting, vomiting and diarrhea were carefully registered and have been correlated with the variations in prostaglandin levels. The effect of therapy with a prostaglandin synthetase inhibitor and a beta-adrenergic drug on prostaglandin levels was also studied. The rise of prostaglandin E2 level observed during implantation is discussed.

Topics: Abortion, Spontaneous; Adult; Chorionic Gonadotropin; Corpus Luteum; Dinoprost; Embryo Implantation; Female; Humans; Lactation; Pregnancy; Progesterone; Prostaglandins; Prostaglandins E; Prostaglandins F

1980