Compounds > 15-hydroperoxy-5-8-11-13-eicosatetraenoic-acid

15-hydroperoxy-5-8-11-13-eicosatetraenoic-acid and Breast-Neoplasms

15-hydroperoxy-5-8-11-13-eicosatetraenoic-acid has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 15-hydroperoxy-5-8-11-13-eicosatetraenoic-acid and Breast-Neoplasms

Article	Year
Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture. Cancer letters, 1989, Jul-15, Volume: 46, Issue:2 Monolayer cultures of MCF-7 human breast cancer cell line were treated with arachidonic acid (AA) and 15-L-(s)-hydroperoxyeicosatetraenoic acid (15-L-(s)-HPETE) in a concentration range of 10(-5)-10(-11) M and their relative cytotoxic potential was determined. Both compounds had a time and dose-dependent cytotoxic effect on MCF-7 cells. 15-L-(S)-HPETE, the 15-lipoxygenase product of AA was the most effective. Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Cell Division; Humans; Leukotrienes; Lipid Peroxides; Tumor Cells, Cultured	1989

Article

Year

Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture.

Cancer letters, 1989, Jul-15, Volume: 46, Issue:2

Monolayer cultures of MCF-7 human breast cancer cell line were treated with arachidonic acid (AA) and 15-L-(s)-hydroperoxyeicosatetraenoic acid (15-L-(s)-HPETE) in a concentration range of 10(-5)-10(-11) M and their relative cytotoxic potential was determined. Both compounds had a time and dose-dependent cytotoxic effect on MCF-7 cells. 15-L-(S)-HPETE, the 15-lipoxygenase product of AA was the most effective.

Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Cell Division; Humans; Leukotrienes; Lipid Peroxides; Tumor Cells, Cultured

1989