15-16-dihydro-11-methylcyclopenta(a)phenanthren-17-one and Lung-Neoplasms

15-16-dihydro-11-methylcyclopenta(a)phenanthren-17-one has been researched along with Lung-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 15-16-dihydro-11-methylcyclopenta(a)phenanthren-17-one and Lung-Neoplasms

ArticleYear
Tumours of mesothelial origin in rats following inoculation with biogenic silica fibres.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Pleural implant experiments using Sprague-Dawley rats have shown that those injected with the carcinogen 15,16-dihydro-11-methylcyclopenta[a]phenenthren-17-one (11-methyl-17-ketone) intraperitoneally followed by silica fibres intrapleurally develop mesotheliomas. These tumours were histologically similar to those induced by crocidolite alone. The intraperitoneal injection of 11-methyl-17-ketone also induced leukaemia.

    Topics: Adenoma; Animals; Carcinogens; Gonanes; Injections; Injections, Intraperitoneal; Leukemia, Myeloid; Lung Neoplasms; Male; Mesothelioma; Papilloma; Pleura; Rats; Rats, Inbred Strains; Silicon Dioxide

1991