15-16-dihydro-11-methylcyclopenta(a)phenanthren-17-one has been researched along with Leukemia--Myeloid* in 1 studies
1 other study(ies) available for 15-16-dihydro-11-methylcyclopenta(a)phenanthren-17-one and Leukemia--Myeloid
Article | Year |
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Tumours of mesothelial origin in rats following inoculation with biogenic silica fibres.
Pleural implant experiments using Sprague-Dawley rats have shown that those injected with the carcinogen 15,16-dihydro-11-methylcyclopenta[a]phenenthren-17-one (11-methyl-17-ketone) intraperitoneally followed by silica fibres intrapleurally develop mesotheliomas. These tumours were histologically similar to those induced by crocidolite alone. The intraperitoneal injection of 11-methyl-17-ketone also induced leukaemia. Topics: Adenoma; Animals; Carcinogens; Gonanes; Injections; Injections, Intraperitoneal; Leukemia, Myeloid; Lung Neoplasms; Male; Mesothelioma; Papilloma; Pleura; Rats; Rats, Inbred Strains; Silicon Dioxide | 1991 |