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14,15-epoxy-5,8,11-eicosatrienoic acid and Pregnancy

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Pregnancy in 7 studies

14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Preeclampsia is a serious complication of pregnancy characterized by the development of vasospasm, hypertension and often associated with proteinuria after the 20th week of gestation."1.46The role of soluble epoxide hydrolase in preeclampsia. ( Joiakim, A; Kim, H; Park, JA; Putt, DA; Santos, JM; Taylor, RN, 2017)
"In 2 independent rat models of preeclampsia, reduced uterine-perfusion rat and the transgenic angiotensin II rat, we observed elevated EET, dihydroxyeicosatrienoic acid, and preeclamptic features that were ameliorated by the CYP epoxygenase inhibitor N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide (MsPPOH)."1.38Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. ( Brewer, J; Dechend, R; Ekholm, E; Gauster, M; Herse, F; Hoyer, J; Hubel, CA; Huppertz, B; Kaartokallio, T; Kacik, M; Laivuori, H; Lamarca, B; Lokki, AI; Luft, FC; Muller, DN; Novotny, S; Park, JK; Rothe, M; Ryan, MJ; Schunck, WH; Staff, AC; Sugulle, M; Verlohren, S; Wallukat, G, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santos, JM1
Park, JA1
Joiakim, A1
Putt, DA1
Taylor, RN1
Kim, H1
Herse, F1
Lamarca, B1
Hubel, CA1
Kaartokallio, T1
Lokki, AI1
Ekholm, E1
Laivuori, H1
Gauster, M1
Huppertz, B1
Sugulle, M1
Ryan, MJ1
Novotny, S1
Brewer, J1
Park, JK1
Kacik, M1
Hoyer, J1
Verlohren, S1
Wallukat, G1
Rothe, M1
Luft, FC1
Muller, DN1
Schunck, WH1
Staff, AC1
Dechend, R1
Koerner, IP1
Jacks, R1
DeBarber, AE1
Koop, D1
Mao, P1
Grant, DF1
Alkayed, NJ1
Schäfer, W1
Werner, K1
Schweer, H1
Schneider, J1
Zahradnik, HP1
Catella, F2
Lawson, J1
Braden, G1
Fitzgerald, DJ2
Shipp, E1
FitzGerald, GA2
Lawson, JA1
Patel, L1
Sullivan, MH1
Elder, MG1

Other Studies

7 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Pregnancy

ArticleYear
The role of soluble epoxide hydrolase in preeclampsia.
    Medical hypotheses, 2017, Volume: 108

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Antihypertensive Agents; Blood Pressure; Epoprostenol; Epoxide H

2017
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
    Circulation, 2012, Dec-18, Volume: 126, Issue:25

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyto

2012
Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Apr-25, Volume: 27, Issue:17

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Ce

2007
Formation of cytochrome P450 metabolites of arachidonic acid by human placenta.
    Advances in experimental medicine and biology, 1997, Volume: 433

    Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acids; Calcimycin; Cytochrome P-450 Enzyme System; Female;

1997
Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,1

1991
Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:15

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Dogs; Fatty Acids, Unsaturated; Female; Gas Chromatography-Mas

1990
Production of epoxygenase metabolite by human reproductive tissues.
    Prostaglandins, 1989, Volume: 38, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Arachidonic Acids; Benzoflavones; Dinopro

1989