14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Pre-Eclampsia in 4 studies
14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preeclampsia is a serious complication of pregnancy characterized by the development of vasospasm, hypertension and often associated with proteinuria after the 20th week of gestation." | 1.46 | The role of soluble epoxide hydrolase in preeclampsia. ( Joiakim, A; Kim, H; Park, JA; Putt, DA; Santos, JM; Taylor, RN, 2017) |
| "In 2 independent rat models of preeclampsia, reduced uterine-perfusion rat and the transgenic angiotensin II rat, we observed elevated EET, dihydroxyeicosatrienoic acid, and preeclamptic features that were ameliorated by the CYP epoxygenase inhibitor N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide (MsPPOH)." | 1.38 | Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. ( Brewer, J; Dechend, R; Ekholm, E; Gauster, M; Herse, F; Hoyer, J; Hubel, CA; Huppertz, B; Kaartokallio, T; Kacik, M; Laivuori, H; Lamarca, B; Lokki, AI; Luft, FC; Muller, DN; Novotny, S; Park, JK; Rothe, M; Ryan, MJ; Schunck, WH; Staff, AC; Sugulle, M; Verlohren, S; Wallukat, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santos, JM | 1 |
| Park, JA | 1 |
| Joiakim, A | 1 |
| Putt, DA | 1 |
| Taylor, RN | 1 |
| Kim, H | 1 |
| Herse, F | 1 |
| Lamarca, B | 1 |
| Hubel, CA | 1 |
| Kaartokallio, T | 1 |
| Lokki, AI | 1 |
| Ekholm, E | 1 |
| Laivuori, H | 1 |
| Gauster, M | 1 |
| Huppertz, B | 1 |
| Sugulle, M | 1 |
| Ryan, MJ | 1 |
| Novotny, S | 1 |
| Brewer, J | 1 |
| Park, JK | 1 |
| Kacik, M | 1 |
| Hoyer, J | 1 |
| Verlohren, S | 1 |
| Wallukat, G | 1 |
| Rothe, M | 1 |
| Luft, FC | 1 |
| Muller, DN | 1 |
| Schunck, WH | 1 |
| Staff, AC | 1 |
| Dechend, R | 1 |
| Catella, F | 2 |
| Lawson, J | 1 |
| Braden, G | 1 |
| Fitzgerald, DJ | 2 |
| Shipp, E | 1 |
| FitzGerald, GA | 2 |
| Lawson, JA | 1 |
4 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Pre-Eclampsia
| Article | Year |
|---|---|
The role of soluble epoxide hydrolase in preeclampsia.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Antihypertensive Agents; Blood Pressure; Epoprostenol; Epoxide H | 2017 |
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyto | 2012 |
Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,1 | 1991 |
Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Dogs; Fatty Acids, Unsaturated; Female; Gas Chromatography-Mas | 1990 |