Page last updated: 2024-10-21

14,15-epoxy-5,8,11-eicosatrienoic acid and Hypertension, Renovascular

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Hypertension, Renovascular in 2 studies

14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation

Hypertension, Renovascular: Hypertension due to RENAL ARTERY OBSTRUCTION or compression.

Research Excerpts

ExcerptRelevanceReference
"We propose that reduced vasodilatory action and decreased intrarenal bioavailability of EETs combined with intrarenal angiotensin II levels that are inappropriately high for hypertensive rats underlie functional derangements of the nonclipped kidneys of 2-kidney, 1-clip Goldblatt hypertensive rats."1.43Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. ( Červenka, L; Falck, JR; Imig, JD; Kopkan, L; Reddy, RN; Sadowski, J; Sporková, A, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alánová, P1
Husková, Z1
Kopkan, L2
Sporková, A2
Jíchová, Š1
Neckář, J1
Imig, JD2
Klevstig, M1
Kolář, F1
Rami Reddy, N1
Falck, JR2
Sadowski, J2
Nishiyama, A1
Kramer, HJ1
Melenovský, V1
Červenková, L1
Kujal, P1
Vernerová, Z1
Červenka, L2
Reddy, RN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Plasmatic Levels of Epoxyeicosatrienoic and Dihydroxyeicosatrienoic Acids in Heart Failure[NCT05305170]100 participants (Anticipated)Observational [Patient Registry]2021-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Hypertension, Renovascular

ArticleYear
Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
    Vascular pharmacology, 2015, Volume: 73

    Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Blood Pressure Monitorin

2015
Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.
    The American journal of the medical sciences, 2016, Volume: 351, Issue:5

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Hypertension, Renovascular; Kidney; Male; Rats; Rats, Sprague-

2016