14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Disease Models, Animal in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H; Geng, H; Gu, W; Tang, J; Wang, L; Wang, Y; Zhao, H | 1 |
| Guan, Y; Jia, YL; Jiang, JX; Liu, Q; Shen, HJ; Shen, J; Xie, QM; Zhang, LH; Zhu, YL | 1 |
| Chen, J; Chen, Q; Fan, Z; Jiang, X; Sun, Y; Wu, J; Xiao, Q; Zhao, Y | 1 |
| Imig, JD; Jankiewicz, WK; Khan, AH | 1 |
| Deng, XF; Huang, Y; Jia, M; Luo, J; Wang, YQ; Yao, JF; Zheng, XD; Zhu, JH | 1 |
| Chen, X; Feng, M; Hu, R; Li, J; Li, Z; Wan, L; Yao, W; Zhang, B; Zhang, C; Zhang, Y | 1 |
| Alkayed, NJ; Anderson, VC; Borkar, RN; Cetas, JS; Dogan, A; Fairbanks, SL; Liu, JJ; Martini, RP; Nelson, JW; Raskin, JS; Siler, DA; Wang, RK; Ward, JP; Zuloaga, KL | 1 |
| Chen, G; Edin, ML; Wang, DW; Wang, P; Wang, Y; Xu, R; Zeldin, DC; Zhang, S | 1 |
| Imig, JD | 1 |
| Alánová, P; Červenka, L; Červenková, L; Falck, JR; Husková, Z; Imig, JD; Jíchová, Š; Klevstig, M; Kolář, F; Kopkan, L; Kramer, HJ; Kujal, P; Melenovský, V; Neckář, J; Nishiyama, A; Rami Reddy, N; Sadowski, J; Sporková, A; Vernerová, Z | 1 |
| Froogh, G; Huang, A; Kandhi, S; Luo, M; Qin, J; Sun, D; Wolin, MS | 1 |
| Guan, H; Li, F; Li, J; Li, L; Liu, H; Mi, B; Tan, P; Zhang, Y; Zhao, L | 1 |
| Alkayed, NJ; Cao, Z; Iliff, J; Liu, L; Merkel, MJ; Motoki, A; Packwood, WH; Van Winkle, DM | 1 |
| Alkayed, NJ; Cao, Z; Liu, L; Merkel, MJ; Packwood, W; Van Winkle, DM; Young, J | 1 |
| Croze, R; Levy, BD; Pfeffer, MA; Planagumà, A; Rubin, G; Serhan, CN; Uddin, M | 1 |
| Baker, JE; Falck, JR; Gross, GJ; Hsu, A; Nithipatikom, K; Wu, HE | 1 |
| Harder, DR; Narayanan, J; Sarkar, P | 1 |
| Dunn, BE; Dunn, LK; Falck, JR; Gruenloh, SK; Jacobs, ER; Medhora, M; Reddy, DS | 1 |
| Alvarez, DF; King, JA; Townsley, MI | 1 |
| Chiang, PC; Fujiwara, H; Ghosh, S; Roberds, SL; Selbo, JG; Wahlstrom, JL | 1 |
| Campbell, WB; Falck, JR; Gauthier, KM; Gross, GJ; Hammock, BD; Moore, J; Nithipatikom, K | 1 |
1 review(s) available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Disease Models, Animal
| Article | Year |
|---|---|
Epoxyeicosatrienoic acids, hypertension, and kidney injury.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antihypertensive Agents; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Fatty Acids; Humans; Hypertension; Kidney Diseases; Mice; Rats | 2015 |
20 other study(ies) available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Disease Models, Animal
| Article | Year |
|---|---|
14,15-EET Reduced Brain Injury from Cerebral Ischemia and Reperfusion via Suppressing Neuronal Parthanatos.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Brain Injuries; Brain Ischemia; Disease Models, Animal; Glucose; Male; Mice; Models, Biological; Neurons; Neuroprotective Agents; Oxidative Stress; Parthanatos; Reactive Oxygen Species; Reperfusion Injury | 2021 |
Inhibition of soluble epoxide hydrolase attenuates airway remodeling in a chronic asthma model.
Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Disease Models, Animal; Epoxide Hydrolases; Female; Humans; Lauric Acids; Lung; MAP Kinase Signaling System; Mice; Ovalbumin; Signal Transduction; STAT3 Transcription Factor | 2020 |
Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway.
Topics: 8,11,14-Eicosatrienoic Acid; AMP-Activated Protein Kinases; Animals; Blood-Brain Barrier; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction | 2020 |
Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiovascular Diseases; Cytochrome P-450 Enzyme System; Disease Models, Animal; Epoxide Hydrolases; Forecasting; Humans; Hypertension; Kidney; Kidney Diseases; Mice; Natriuresis; Potassium; Rats; Rats, Inbred Dahl; Sodium Chloride; Sodium Chloride, Dietary; Vasodilation; Water-Electrolyte Balance; Water-Electrolyte Imbalance | 2020 |
14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Humans; Immunohistochemistry; Integrin alphaVbeta3; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2018 |
Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors.
Topics: 8,11,14-Eicosatrienoic Acid; Analgesics; Animals; Cerebral Hemorrhage; Disease Models, Animal; Gabapentin; Hyperalgesia; Male; Pregnanolone; Proof of Concept Study; Random Allocation; Rats, Sprague-Dawley; Receptors, GABA-A; Stroke; Thalamus | 2019 |
Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage.
Topics: 8,11,14-Eicosatrienoic Acid; Aged; Animals; Brain Ischemia; Disease Models, Animal; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Mice; Middle Aged; Neuroprotective Agents; Subarachnoid Hemorrhage | 2015 |
CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice.
Topics: 8,11,14-Eicosatrienoic Acid; Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytokines; Diet, High-Fat; Disease Models, Animal; Glutathione Peroxidase; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Palmitic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Superoxide Dismutase; Triglycerides | 2015 |
Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydroxyeicosatetraenoic Acids; Hypertension, Renovascular; Kidney; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Telemetry; Time Factors | 2015 |
EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arterial Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypoxia; Infusions, Intravenous; Male; Mice, Inbred C57BL; Pulmonary Artery; Time Factors; Ventricular Function, Right; Ventricular Pressure | 2016 |
Epoxyeicosanoids prevent intervertebral disc degeneration in vitro and in vivo.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Hydrogen Peroxide; Intervertebral Disc Degeneration; Male; NF-kappa B; Nucleus Pulposus; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo.
Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Animals; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Female; Gene Deletion; Heart Ventricles; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Time Factors; Urea | 2008 |
Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Epoxide Hydrolases; Janus Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myocardial Reperfusion Injury; Myocytes, Cardiac; Polymorphism, Single Nucleotide; Signal Transduction; STAT3 Transcription Factor | 2010 |
Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4.
Topics: 8,11,14-Eicosatrienoic Acid; Acute Disease; Animals; Anticholesteremic Agents; Cell Line; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Inflammation; Inflammation Mediators; Lipoxins; Lovastatin; Male; Mice; Neutrophils; Pneumonia; Respiratory Mucosa | 2010 |
Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts.
Topics: 8,11,14-Eicosatrienoic Acid; Analgesics, Opioid; Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin | 2010 |
Differential effect of amyloid β on the cytochrome P450 epoxygenase activity in rat brain.
Topics: 8,11,14-Eicosatrienoic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Male; Neuroprotective Agents; Primary Cell Culture; Rats; Rats, Sprague-Dawley | 2011 |
Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs).
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Capillaries; Chick Embryo; Chorioallantoic Membrane; Culture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperemia; Neovascularization, Physiologic; Nitric Oxide Donors; Time Factors; Vasodilator Agents; Vitelline Membrane | 2005 |
Resistance to store depletion-induced endothelial injury in rat lung after chronic heart failure.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Calcimycin; Calcium Channels; Calcium-Transporting ATPases; Disease Models, Animal; Endothelium; Enzyme Inhibitors; Heart Failure; Ionophores; Lung; Permeability; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Tissue Culture Techniques; Vasodilator Agents | 2005 |
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Chromatography, Liquid; Disease Models, Animal; Epoxide Hydrolases; Hypertension; Male; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Solubility; Suspensions; Tandem Mass Spectrometry; Urea | 2008 |
Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.
Topics: 8,11,14-Eicosatrienoic Acid; Adamantane; Animals; Blood Pressure; Cardiovascular Agents; Coronary Circulation; Diazoxide; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoxide Hydrolases; Female; Heart Rate; Lauric Acids; Male; Mitochondria, Heart; Myocardial Infarction; Myocardium; Potassium Channels | 2008 |