14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Cardiomegaly in 4 studies
14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, it is important to examine whether fenofibrate would modulate the cardiac P450 and its associated arachidonic acid metabolites and whether this modulation protects against isoproterenol-induced cardiac hypertrophy." | 7.80 | Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. ( Althurwi, HN; El-Kadi, AO; Elshenawy, OH, 2014) |
| " Therefore, it is important to examine whether fenofibrate would modulate the cardiac P450 and its associated arachidonic acid metabolites and whether this modulation protects against isoproterenol-induced cardiac hypertrophy." | 3.80 | Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. ( Althurwi, HN; El-Kadi, AO; Elshenawy, OH, 2014) |
| "Diabetic cardiac hypertrophy was developed by high-fat diet feeding combined with streptozotocin (40 mg/kg/d for 5 days, i." | 1.72 | 14,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs. ( Ding, S; Jiang, C; Jiang, Q; Qiu, H; Wu, K; Yang, C; Yang, J; Zhang, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Yang, C | 1 |
| Qiu, H | 1 |
| Yang, J | 1 |
| Wu, K | 1 |
| Ding, S | 1 |
| Jiang, C | 1 |
| Jiang, Q | 1 |
| Wang, X | 1 |
| Ni, L | 1 |
| Yang, L | 1 |
| Duan, Q | 1 |
| Chen, C | 1 |
| Edin, ML | 1 |
| Zeldin, DC | 1 |
| Wang, DW | 1 |
| Althurwi, HN | 1 |
| Elshenawy, OH | 2 |
| El-Kadi, AO | 2 |
| Amara, IE | 1 |
| Abdelrady, M | 1 |
4 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Cardiomegaly
| Article | Year |
|---|---|
14,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cardiomegaly; Diabetes Mellitus; Diabetic Cardiomyopathies; Gl | 2022 |
CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Apoptosis; Calcium; Cardiomegaly; Cell Line; Cytochrome P-450 | 2014 |
Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiomegaly; Cytochrome P-450 CYP2J2; Cytoc | 2014 |
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Atrial Natriuretic Factor; Biomarkers; Cardi | 2014 |