Page last updated: 2024-10-21

14,15-epoxy-5,8,11-eicosatrienoic acid and Cardiac Hypertrophy

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Cardiac Hypertrophy in 4 studies

14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
" Therefore, it is important to examine whether fenofibrate would modulate the cardiac P450 and its associated arachidonic acid metabolites and whether this modulation protects against isoproterenol-induced cardiac hypertrophy."7.80Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. ( Althurwi, HN; El-Kadi, AO; Elshenawy, OH, 2014)
" Therefore, it is important to examine whether fenofibrate would modulate the cardiac P450 and its associated arachidonic acid metabolites and whether this modulation protects against isoproterenol-induced cardiac hypertrophy."3.80Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy. ( Althurwi, HN; El-Kadi, AO; Elshenawy, OH, 2014)
"Diabetic cardiac hypertrophy was developed by high-fat diet feeding combined with streptozotocin (40 mg/kg/d for 5 days, i."1.7214,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs. ( Ding, S; Jiang, C; Jiang, Q; Qiu, H; Wu, K; Yang, C; Yang, J; Zhang, J, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Zhang, J1
Yang, C1
Qiu, H1
Yang, J1
Wu, K1
Ding, S1
Jiang, C1
Jiang, Q1
Wang, X1
Ni, L1
Yang, L1
Duan, Q1
Chen, C1
Edin, ML1
Zeldin, DC1
Wang, DW1
Althurwi, HN1
Elshenawy, OH2
El-Kadi, AO2
Amara, IE1
Abdelrady, M1

Other Studies

4 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Cardiac Hypertrophy

ArticleYear
14,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs.
    Prostaglandins & other lipid mediators, 2022, Volume: 159

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cardiomegaly; Diabetes Mellitus; Diabetic Cardiomyopathies; Gl

2022
CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.
    Molecular pharmacology, 2014, Volume: 85, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Apoptosis; Calcium; Cardiomegaly; Cell Line; Cytochrome P-450

2014
Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy.
    Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiomegaly; Cytochrome P-450 CYP2J2; Cytoc

2014
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart.
    Toxicology letters, 2014, Apr-07, Volume: 226, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Atrial Natriuretic Factor; Biomarkers; Cardi

2014