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14,15-epoxy-5,8,11-eicosatrienoic acid and Breast Cancer

14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Breast Cancer in 3 studies

14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation

Research Excerpts

ExcerptRelevanceReference
"The role of 14, 15-EET in breast cancer cell adhesion, invasion was explored by adhesion and Transwell assays."1.4814, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling. ( Deng, XF; Huang, Y; Jia, M; Luo, J; Wang, YQ; Yao, JF; Zheng, XD; Zhu, JH, 2018)
"CYP3A4 expression in breast cancer correlates with decreased overall survival, but the mechanisms are unknown."1.37CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). ( Blair, IA; Capdevila, J; Clarke, D; Donner, DB; Falck, JR; Guo, Z; Gupta, K; Lamba, J; Luo, X; Mesaros, C; Milani, M; Mitra, R; Nguyen, J; Potter, DA; Puli, N; Rodriguez, M; Schuetz, E, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luo, J1
Yao, JF1
Deng, XF1
Zheng, XD1
Jia, M1
Wang, YQ1
Huang, Y1
Zhu, JH1
Wei, X1
Zhang, D1
Dou, X1
Niu, N1
Huang, W1
Bai, J1
Zhang, G1
Mitra, R1
Guo, Z1
Milani, M1
Mesaros, C1
Rodriguez, M1
Nguyen, J1
Luo, X1
Clarke, D1
Lamba, J1
Schuetz, E1
Donner, DB1
Puli, N1
Falck, JR1
Capdevila, J1
Gupta, K1
Blair, IA1
Potter, DA1

Other Studies

3 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Breast Cancer

ArticleYear
14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling.
    Journal of experimental & clinical cancer research : CR, 2018, Feb-09, Volume: 37, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Moveme

2018
Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer.
    BMC cancer, 2014, Nov-18, Volume: 14

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2014
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET).
    The Journal of biological chemistry, 2011, May-20, Volume: 286, Issue:20

    Topics: 8,11,14-Eicosatrienoic Acid; Active Transport, Cell Nucleus; Breast Neoplasms; Cell Division; Cell L

2011