14,15-epoxy-5,8,11-eicosatrienoic acid has been researched along with Blood Pressure, High in 14 studies
14,15-epoxy-5,8,11-eicosatrienoic acid: RN given refers to cpd without isomeric designation
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taken together, these data support the concept that renal microvascular 11,12-EET activity and levels may not properly offset the enhanced angiotensin II renal vasoconstriction during angiotensin II hypertension." | 7.71 | Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. ( Capdevila, JH; Falck, JR; Imig, JD; Wei, S; Zhao, X, 2001) |
| "Taken together, these data support the concept that renal microvascular 11,12-EET activity and levels may not properly offset the enhanced angiotensin II renal vasoconstriction during angiotensin II hypertension." | 3.71 | Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. ( Capdevila, JH; Falck, JR; Imig, JD; Wei, S; Zhao, X, 2001) |
| "Preeclampsia is a serious complication of pregnancy characterized by the development of vasospasm, hypertension and often associated with proteinuria after the 20th week of gestation." | 1.46 | The role of soluble epoxide hydrolase in preeclampsia. ( Joiakim, A; Kim, H; Park, JA; Putt, DA; Santos, JM; Taylor, RN, 2017) |
| " 1,3-dicyclohexylurea (DCU), a potent sEH inhibitor, lowers systemic blood pressure in spontaneously hypertensive rats when dosed intraperitoneally." | 1.35 | Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. ( Chiang, PC; Fujiwara, H; Ghosh, S; Roberds, SL; Selbo, JG; Wahlstrom, JL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Imig, JD | 4 |
| Jankiewicz, WK | 1 |
| Khan, AH | 1 |
| Campbell, WB | 1 |
| Schmitz, JM | 1 |
| Falck, JR | 4 |
| Santos, JM | 1 |
| Park, JA | 1 |
| Joiakim, A | 1 |
| Putt, DA | 1 |
| Taylor, RN | 1 |
| Kim, H | 1 |
| Yang, C | 1 |
| Yang, J | 1 |
| Xu, X | 1 |
| Yan, S | 1 |
| Pan, S | 1 |
| Pan, X | 1 |
| Zhang, C | 1 |
| Leung, GP | 1 |
| Sporková, A | 1 |
| Husková, Z | 1 |
| Škaroupková, P | 1 |
| Rami Reddy, N | 1 |
| Sadowski, J | 1 |
| Červenka, L | 1 |
| Pidkovka, N | 1 |
| Rao, R | 1 |
| Mei, S | 1 |
| Gong, Y | 1 |
| Harris, RC | 1 |
| Wang, WH | 1 |
| Capdevila, JH | 2 |
| Ghosh, S | 1 |
| Chiang, PC | 1 |
| Wahlstrom, JL | 1 |
| Fujiwara, H | 1 |
| Selbo, JG | 1 |
| Roberds, SL | 1 |
| Ma, YH | 1 |
| Schwartzman, ML | 1 |
| Roman, RJ | 1 |
| Yu, Z | 2 |
| Huse, LM | 2 |
| Adler, P | 1 |
| Graham, L | 2 |
| Ma, J | 1 |
| Zeldin, DC | 2 |
| Kroetz, DL | 2 |
| Xu, F | 1 |
| Morisseau, C | 1 |
| Draper, AJ | 1 |
| Newman, JW | 1 |
| Parker, C | 1 |
| Engler, MM | 1 |
| Hammock, BD | 1 |
| Zhao, X | 1 |
| Wei, S | 1 |
| Catella, F | 1 |
| Lawson, JA | 1 |
| Fitzgerald, DJ | 1 |
| FitzGerald, GA | 1 |
| Lin, WK | 1 |
| Wong, PY | 1 |
2 reviews available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Blood Pressure, High
| Article | Year |
|---|---|
Orally Active Epoxyeicosatrienoic Acid Analogs.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Cardiovascular Diseases; | 2017 |
Epoxyeicosatrienoic acids, hypertension, and kidney injury.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antihypertensive Agents; Disease Models, Animal; Disease Progr | 2015 |
12 other studies available for 14,15-epoxy-5,8,11-eicosatrienoic acid and Blood Pressure, High
| Article | Year |
|---|---|
Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiovascular Diseases; Cytochrome P-450 En | 2020 |
The role of soluble epoxide hydrolase in preeclampsia.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Antihypertensive Agents; Blood Pressure; Epoprostenol; Epoxide H | 2017 |
Vasodilatory effect of 14,15-epoxyeicosatrienoic acid on mesenteric arteries in hypertensive and aged rats.
Topics: 8,11,14-Eicosatrienoic Acid; Aging; Animals; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vasc | 2014 |
Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimenta
Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Animals; Disease Progression; Dose-Response Relationship | 2017 |
Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant | 2013 |
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Chromatography, Liquid; | 2008 |
Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cytoch | 1994 |
Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Hyper | 2000 |
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Blood Pressure; Cytosol; Eicosanoids; Enzym | 2000 |
Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Animals; Arterioles; Cytochrome P-450 CYP2J2; Cytochrom | 2001 |
Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Dogs; Fatty Acids, Unsaturated; Female; Gas Chromatography-Mas | 1990 |
Effect of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antihypertensive Agents; Blood Pressure; Diterpenes; Dose-Resp | 1990 |