Compounds > 13-hydroxy-9-11-octadecadienoic-acid

13-hydroxy-9-11-octadecadienoic-acid and Edema

13-hydroxy-9-11-octadecadienoic-acid has been researched along with Edema* in 1 studies

Other Studies

1 other study(ies) available for 13-hydroxy-9-11-octadecadienoic-acid and Edema

Article	Year
13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3 Intradermal 13-hydroxyoctadecadienoic acid (13-HODE; 10(-11)-10(-9) mol/site) inhibited oedema formation induced by the neutrophil-dependent mediator leukotriene B4 (LTB4) in the presence of calcitonin gene-related peptide (CGRP; 10(-11) mol/site) in rabbit skin. In contrast, the responses to the direct acting mediators bradykinin and histamine were unaffected by 13-HODE. 13-HODE failed to induce oedema formation in rabbit skin when injected alone or in the presence of the potent vasodilator CGRP. These results present a novel interaction between 13-HODE and LTB4 that could have important implications in the pathogenesis of inflammation. Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Edema; Leukotriene B4; Linoleic Acids; Rabbits; Skin	1992

Article

Year

13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin.

European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3

Intradermal 13-hydroxyoctadecadienoic acid (13-HODE; 10(-11)-10(-9) mol/site) inhibited oedema formation induced by the neutrophil-dependent mediator leukotriene B4 (LTB4) in the presence of calcitonin gene-related peptide (CGRP; 10(-11) mol/site) in rabbit skin. In contrast, the responses to the direct acting mediators bradykinin and histamine were unaffected by 13-HODE. 13-HODE failed to induce oedema formation in rabbit skin when injected alone or in the presence of the potent vasodilator CGRP. These results present a novel interaction between 13-HODE and LTB4 that could have important implications in the pathogenesis of inflammation.

Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Edema; Leukotriene B4; Linoleic Acids; Rabbits; Skin

1992