13(S)-HODE and Carcinoma--Hepatocellular

13(S)-HODE has been researched along with Carcinoma--Hepatocellular* in 1 studies

Other Studies

1 other study(ies) available for 13(S)-HODE and Carcinoma--Hepatocellular

Article	Year
Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of natural products, 2003, Volume: 66, Issue:8 Two new C-18 norwithanolides based on a C(27) skeleton, subtrifloralactones K (1) and L (2), a new C-18 oxygenated withanolide, 13 beta-hydroxymethylsubtrifloralactone E (3), and a new alpha-ionone derivative, (+)-7 alpha,8 alpha-epoxyblumenol B (4), along with five known compounds, philadelphicalactone A (5), (2S,3S,4R)-2-[(2R)-2'-hydroxytetracosanoylamino]-1,3,4-octadecanetriol (6), trans-N-feruloyltyramine, cis-N-feruloyltyramine, and (S)-coriolic acid, were isolated from additional active fractions of the chloroform-soluble extract of Deprea subtriflora, using a quinone reductase (QR) induction assay as a monitor. The structures of compounds 1-4 were characterized by spectroscopic data interpretation. The potential cancer chemopreventive activities of all isolates in terms of their ability to induce QR activity with cultured Hepa 1c1c7 mouse hepatoma cells were evaluated. Topics: Animals; Carcinoma, Hepatocellular; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 4 or More Rings; Lactones; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Nuclear Magnetic Resonance, Biomolecular; Solanaceae; Stereoisomerism; Tumor Cells, Cultured	2003

Article

Year

Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora.

Journal of natural products, 2003, Volume: 66, Issue:8

Two new C-18 norwithanolides based on a C(27) skeleton, subtrifloralactones K (1) and L (2), a new C-18 oxygenated withanolide, 13 beta-hydroxymethylsubtrifloralactone E (3), and a new alpha-ionone derivative, (+)-7 alpha,8 alpha-epoxyblumenol B (4), along with five known compounds, philadelphicalactone A (5), (2S,3S,4R)-2-[(2R)-2'-hydroxytetracosanoylamino]-1,3,4-octadecanetriol (6), trans-N-feruloyltyramine, cis-N-feruloyltyramine, and (S)-coriolic acid, were isolated from additional active fractions of the chloroform-soluble extract of Deprea subtriflora, using a quinone reductase (QR) induction assay as a monitor. The structures of compounds 1-4 were characterized by spectroscopic data interpretation. The potential cancer chemopreventive activities of all isolates in terms of their ability to induce QR activity with cultured Hepa 1c1c7 mouse hepatoma cells were evaluated.

Topics: Animals; Carcinoma, Hepatocellular; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 4 or More Rings; Lactones; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Nuclear Magnetic Resonance, Biomolecular; Solanaceae; Stereoisomerism; Tumor Cells, Cultured

2003