12-deoxyphorbol-13-acetate has been researched along with Burkitt-Lymphoma* in 1 studies
1 other study(ies) available for 12-deoxyphorbol-13-acetate and Burkitt-Lymphoma
| Article | Year |
|---|---|
Diterpenoids from the roots of Euphorbia fischeriana.
From the dried roots of Euphorbia fischeriana, seven new diterpenoids, 3alpha,17-dihydroxy-ent-pimara-8(14),15-diene (1), 7beta,11beta,12beta-trihydroxy-ent-abieta-8(14),13(15)-dien-16,12-olide (2), 17-acetoxyjolkinolide B (3), 13beta-hydroxy-ent-abiet-8(14)-en-7-one (4), 12-deoxyphorbaldehyde-13-acetate (5) 12-deoxyphorbaldehyde-13-hexadecacetate (6), and 12-deoxyphorbol-13-(9Z)-octadecanoate-20-acetate (7), and two known compounds, 12-deoxyphorbol-13-decanoate (8) and prostratin (9), were isolated. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. The structure of compound 1 was confirmed by single-crystal X-ray crystallography. Compounds 3 and 8 exhibited potent cytotoxic activity to Ramos B cells with IC50 values of 0.023 and 0.0051 microg/mL, respectively. Topics: Antineoplastic Agents, Phytogenic; Burkitt Lymphoma; Diterpenes; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Euphorbia; Humans; Molecular Structure; Plant Roots; Plants, Medicinal; Tumor Cells, Cultured | 2006 |