11-o-galloylbergenin has been researched along with Pain* in 1 studies
1 other study(ies) available for 11-o-galloylbergenin and Pain
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Analgesic and anti-inflammatory activities of 11-O-galloylbergenin.
Current study was designed to explore the analgesic and anti-inflammatory effects of a constituent isolated from Mallotus philippinensis, in order to validate its folk use.. 11-O-galloylbergenin was isolated from ethanolic extract of Mallotus philippinensis. Analgesic and anti-inflammatory activities of the test compound were assessed using formalin test and carrageenan-induced paw edema models.. 11-O-galloylbergenin showed significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats. Similarly, 11-O-galloylbergenin exhibited significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.. 11-O-galloylbergenin has demonstrated its significant potential to be further investigated for its discovery as a new lead compound for management of pain and inflammation. Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzopyrans; Carrageenan; Edema; Euphorbiaceae; Female; Gallic Acid; Inflammation; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Phytotherapy; Plant Extracts; Plant Stems; Rats; Rats, Wistar; Wood | 2010 |