11-dehydrocorticosterone and Myocardial-Infarction

11-dehydrocorticosterone has been researched along with Myocardial-Infarction* in 1 studies

Other Studies

1 other study(ies) available for 11-dehydrocorticosterone and Myocardial-Infarction

ArticleYear
11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI.
    The Journal of endocrinology, 2017, Volume: 233, Issue:3

    We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from intrinsically inert metabolites. The present study aimed to identify the mechanism of regulation. In a mouse model of MI, neutrophil mobilization to blood and recruitment to the heart were higher in 11β-HSD1-deficient (

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Bone Marrow Cells; Cells, Cultured; Chemokine CXCL2; Chemokine CXCL5; Corticosterone; Fibroblasts; Male; Mice; Mice, Knockout; Microfilament Proteins; Muscle Proteins; Myocardial Infarction; Neutrophils

2017