Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and Mucositis

10-propargyl-10-deazaaminopterin has been researched along with Mucositis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foss, FM; Girardi, M; Li, A; Parker, TL1
Evande, RE; Grem, JL; Kos, ME; Meza, JL; Schwarz, JK1
Duffull, SB; Fleisher, M; Hamlin, P; Horwitz, S; Mould, DR; Neylon, E; O'Connor, OA; Saunders, ME; Sirotnak, F; Sweeney, K1
Bartlett, NL; Delioukina, ML; Duvic, M; Fisher, DC; Foss, F; Horwitz, SM; Kim, YH; Koutsoukos, T; Lechowicz, MJ; Myskowski, PL; O'Connor, OA; Saunders, ME; Shustov, AR; Zain, JM1

Trials

2 trial(s) available for 10-propargyl-10-deazaaminopterin and Mucositis

ArticleYear
A phase 1 clinical trial of sequential pralatrexate followed by a 48-hour infusion of 5-fluorouracil given every other week in adult patients with solid tumors.
    Cancer, 2015, Nov-01, Volume: 121, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Folic Acid Antagonists; Gastrointestinal Neoplasms; Humans; Incidence; Male; Middle Aged; Mucositis; Pancreatic Neoplasms; Polymorphism, Genetic; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Time Factors; Treatment Outcome

2015
Identification of an active, well-tolerated dose of pralatrexate in patients with relapsed or refractory cutaneous T-cell lymphoma.
    Blood, 2012, May-03, Volume: 119, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antimetabolites, Antineoplastic; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Fatigue; Female; Gastrointestinal Diseases; Humans; Lymphoma, T-Cell, Cutaneous; Male; Middle Aged; Mucositis; Neutropenia; Salvage Therapy; Skin Neoplasms; Thrombocytopenia

2012

Other Studies

2 other study(ies) available for 10-propargyl-10-deazaaminopterin and Mucositis

ArticleYear
Effect of leucovorin administration on mucositis and skin reactions in patients with peripheral T-cell lymphoma or cutaneous T-cell lymphoma treated with pralatrexate.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Female; Humans; Leucovorin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Mucositis; Neoplasm Staging; Premedication; Retrospective Studies; Skin Diseases; Treatment Outcome

2019
A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:2

    Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Area Under Curve; Biomarkers; Body Size; Drug Administration Schedule; Female; Folic Acid Antagonists; Hodgkin Disease; Humans; Incidence; Lymphoma, Non-Hodgkin; Male; Methylmalonic Acid; Middle Aged; Models, Statistical; Mucositis; Predictive Value of Tests; Recurrence; Severity of Illness Index; Vitamin B 12

2009