Page last updated: 2024-09-04

10-propargyl-10-deazaaminopterin and Lymphoma, T Cell, Peripheral

10-propargyl-10-deazaaminopterin has been researched along with Lymphoma, T Cell, Peripheral in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's21 (75.00)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Altınay, S; Kural, A; Özmen, A; Tural, D; Tutar, Y1
Kaur, H; Lee, YS; Ong, SY; Phipps, C; Tan, L1
Francine, F; Jennifer C, Z; Salma, A; Sara Mohamed, J1
Maeda, Y; Tobinai, K; Yeoh, EM; Zhu, J1
Baik, D; Cho, H; Cho, S; Kang, HY; Kim, AY; Lee, H; Park, S1
Marchi, E; O'Connor, OA; Raufi, AG1
Amengual, J; Colbourn, D; Deng, C; O'Connor, OA; Sawas, A1
Vose, JM1
Gisselbrecht, C; Sibon, D1
Ito, Y; Makita, S; Tobinai, K1
Foss, FM; Girardi, M; Li, A; Parker, TL1
Bhagat, G; Ma, H; O'Connor, OA1
Altuntaş, F; Çakar, MK; Dal, MS; Doğan, M; İskender, D; Merdin, A; Ulu, BU1
Geskin, LJ; Koch, E; Story, SK1
Bari, A; Dondi, A; Ferri, P; Pozzi, S; Sacchi, S1
Gooptu, M; Pro, B; Rhoades, R1
Advani, RH; Ansell, SM; Beaven, AW; Carson, KR; Evens, AM; Foss, F; Horwitz, S; Lechowicz, MJ; Loberiza, F; Pinter-Brown, LC; Pro, B; Savage, KJ; Shustov, AR; Smith, SM; Vose, JM1
Ahn, JS; Cho, MS; Jung, SH; Jung, SY; Kim, HJ; Kim, YK; Lee, JJ; Lee, SS; Yang, DH1
Chihara, D; Davis, RE; Fanale, MA; Fayad, LE; Fowler, NH; Hagemeister, FB; Hosing, C; Lee, HJ; Medeiros, LJ; Miranda, RN; Nastoupil, LJ; Neelapu, SS; Nieto, YL; Noorani, M; Oki, Y; Rodriguez, MA; Romaguera, JE; Samaniego, F; Turturro, F; Wang, M; Westin, JR1
O'Leary, HM; Savage, KJ1
Link, BK; Rosenstein, LJ1
Thompson, CA1
O'Connor, OA1
Bartlett, N; Boyd, A; Coiffier, B; Crump, M; Furman, R; Gisselbrecht, C; Goy, A; Haioun, C; Horwitz, S; Hsi, E; Jacobsen, E; Lechowicz, MJ; O'Connor, OA; Pinter-Brown, L; Popplewell, L; Pro, B; Savage, KJ; Shustov, AR; Zain, JM; Zinzani, PL1
Foss, F1
Elefante, A; Hui, J; Przespo, E1

Reviews

13 review(s) available for 10-propargyl-10-deazaaminopterin and Lymphoma, T Cell, Peripheral

ArticleYear
Pralatrexate for Peripheral T-Cell Lymphoma (PTCL): Chance Only Supports The Prepared Mind.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:3

    Topics: COVID-19; Folic Acid Antagonists; Humans; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Meta-Analysis as Topic; Methotrexate; Neoplasm Recurrence, Local; SARS-CoV-2; Skin Neoplasms; Systematic Reviews as Topic; United States

2023
Pralatrexate injection for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma.
    Expert review of hematology, 2020, Volume: 13, Issue:6

    Topics: Aminopterin; Humans; Lymphoma, T-Cell, Peripheral

2020
Novel Agents in the Treatment of Relapsed or Refractory Peripheral T-Cell Lymphoma.
    Hematology/oncology clinics of North America, 2017, Volume: 31, Issue:2

    Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Brentuximab Vedotin; Clinical Trials as Topic; Depsipeptides; Disease-Free Survival; Hydroxamic Acids; Immunoconjugates; Lymphoma, T-Cell, Peripheral; Sulfonamides; Survival Rate

2017
Pralatrexate: a comprehensive update on pharmacology, clinical activity and strategies to optimize use.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:11

    Topics: Aminopterin; Clinical Trials as Topic; Drug Resistance, Neoplasm; Drug Therapy; Folic Acid Antagonists; Humans; Lymphoma, T-Cell, Peripheral; Neoplasm Recurrence, Local; Treatment Outcome

2017
New perspectives in the therapeutic approach of peripheral T-cell lymphoma.
    Current opinion in oncology, 2018, Volume: 30, Issue:5

    Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Brentuximab Vedotin; Clinical Trials, Phase II as Topic; Depsipeptides; Humans; Hydroxamic Acids; Immunoconjugates; Lymphoma, T-Cell, Peripheral; Randomized Controlled Trials as Topic; Sulfonamides

2018
Development of new agents for peripheral T-cell lymphoma.
    Expert opinion on biological therapy, 2019, Volume: 19, Issue:3

    Topics: Aminopterin; Aminopyridines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Brentuximab Vedotin; China; Depsipeptides; Drug Approval; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoconjugates; Lymphoma, T-Cell, Peripheral; Neoplasm Recurrence, Local; Sulfonamides

2019
A peripheral T-cell lymphoma (PTCL) arising as a post-transplant lymphoproliferative disorder: efficacy of pralatrexate in primary refractory disease and review of the literature.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:13

    Topics: Adult; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cardiomyopathies; Deoxycytidine; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heart Failure; Heart Transplantation; Humans; Lymphoma, T-Cell, Peripheral; Organoplatinum Compounds; Peripartum Period; Positron Emission Tomography Computed Tomography; Postoperative Complications; Treatment Outcome

2019
The potential of pralatrexate as a treatment of peripheral T-cell lymphoma.
    Expert opinion on investigational drugs, 2014, Volume: 23, Issue:5

    Topics: Aminopterin; Animals; Antineoplastic Agents; Clinical Trials as Topic; Folic Acid Antagonists; Humans; Lymphoma, T-Cell, Peripheral; Treatment Outcome

2014
Current management of peripheral T-cell lymphomas.
    Cancer treatment and research, 2015, Volume: 165

    Topics: Aminopterin; Antineoplastic Agents; Brentuximab Vedotin; Diphtheria Toxin; Histone Deacetylase Inhibitors; Humans; Immunoconjugates; Interleukin-2; Lymphoma, T-Cell, Peripheral; Molecular Targeted Therapy; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Stem Cell Transplantation

2015
Novel therapies in peripheral T-cell lymphomas.
    Current oncology reports, 2008, Volume: 10, Issue:5

    Topics: Alemtuzumab; Aminopterin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Diphtheria Toxin; Enzyme Inhibitors; Gemcitabine; Humans; Immunotherapy; Interleukin-2; Lymphoma, T-Cell, Peripheral; Medical Oncology; Prognosis; Recombinant Fusion Proteins; Treatment Outcome

2008
Optimizing chemotherapeutic strategies for peripheral T-cell lymphomas.
    Clinical lymphoma & myeloma, 2008, Volume: 8 Suppl 5

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Delivery Systems; Humans; Lymphoma, T-Cell, Peripheral; Prednisone; Vincristine

2008
Novel agents in development for peripheral T-cell lymphoma.
    Seminars in hematology, 2010, Volume: 47 Suppl 1

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Clinical Trials as Topic; Depsipeptides; Drug Design; Drugs, Investigational; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Lenalidomide; Lymphoma, T-Cell, Peripheral; Purine Nucleosides; Pyrazines; Pyrimidinones; Salvage Therapy; Thalidomide

2010
Pralatrexate: a novel synthetic antifolate for relapsed or refractory peripheral T-cell lymphoma and other potential uses.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2012, Volume: 18, Issue:2

    Topics: Aminopterin; Animals; Clinical Trials as Topic; Folic Acid Antagonists; Humans; Lymphoma, T-Cell, Peripheral; Neoplasm Recurrence, Local

2012

Trials

3 trial(s) available for 10-propargyl-10-deazaaminopterin and Lymphoma, T Cell, Peripheral

ArticleYear
A phase II study of cyclophosphamide, etoposide, vincristine and prednisone (CEOP) alternating with pralatrexate (P) as front line therapy for patients with peripheral T-cell lymphoma (PTCL): preliminary results from the T-Cell Consortium trial.
    Clinical advances in hematology & oncology : H&O, 2014, Volume: 12, Issue:2 Suppl 5

    Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Humans; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Prednisone; Vincristine

2014
A phase II study of cyclophosphamide, etoposide, vincristine and prednisone (CEOP) Alternating with Pralatrexate (P) as front line therapy for patients with peripheral T-cell lymphoma (PTCL): final results from the T- cell consortium trial.
    British journal of haematology, 2016, Volume: 172, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression; Disease-Free Survival; Epirubicin; Female; Humans; Kaplan-Meier Estimate; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Prednisone; Treatment Outcome; Vincristine

2016
Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-20, Volume: 29, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; Humans; International Agencies; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Remission Induction; Salvage Therapy; Standard of Care; Survival Rate; Treatment Outcome; Young Adult

2011

Other Studies

12 other study(ies) available for 10-propargyl-10-deazaaminopterin and Lymphoma, T Cell, Peripheral

ArticleYear
Pralatrexate Induces Long-Term Remission in Relapsed Subcutaneous Panniculitis-Like T-Cell Lymphoma.
    Annals of the Academy of Medicine, Singapore, 2019, Volume: 48, Issue:9

    Topics: Adult; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cisplatin; Cyclophosphamide; Deoxycytidine; Dexamethasone; Doxorubicin; Folic Acid Antagonists; Gemcitabine; Humans; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell, Peripheral; Male; Neoplasm Recurrence, Local; Panniculitis; Prednisone; Remission Induction; Subcutaneous Fat, Abdominal; Vincristine

2019
Efficacy and safety of single-agent pralatrexate for treatment of angioimmunoblastic T-cell lymphoma after failure of first line therapy: a pooled analysis.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:9

    Topics: Aminopterin; China; Humans; Japan; Lymphoma, T-Cell, Peripheral; Neoplasm Recurrence, Local; Prospective Studies; Retrospective Studies

2020
Cost-utility analysis of pralatrexate for relapsed or refractory peripheral T-cell lymphoma based on a case-matched historical control study along with single arm clinical trial.
    BMC cancer, 2020, Nov-26, Volume: 20, Issue:1

    Topics: Aminopterin; Case-Control Studies; Cost-Benefit Analysis; Female; Humans; Lymphoma, T-Cell, Peripheral; Male; Neoplasm Recurrence, Local

2020
Peripheral T-cell lymphoma: novel backbone.
    Blood, 2018, 01-25, Volume: 131, Issue:4

    Topics: Aminopterin; Depsipeptides; Humans; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral

2018
Effect of leucovorin administration on mucositis and skin reactions in patients with peripheral T-cell lymphoma or cutaneous T-cell lymphoma treated with pralatrexate.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Female; Humans; Leucovorin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Mucositis; Neoplasm Staging; Premedication; Retrospective Studies; Skin Diseases; Treatment Outcome

2019
Pralatrexate induced durable response in a relapsed/refractory peripheral T-cell lymphoma patient with a history of autologous stem cell transplantation: Case report of a patient followed-up over 3 years under pralatrexate treatment.
    Medicine, 2019, Volume: 98, Issue:30

    Topics: Aged; Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, T-Cell, Peripheral; Male; Recurrence

2019
Preemptive leucovorin administration minimizes pralatrexate toxicity without sacrificing efficacy.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Female; Folic Acid Antagonists; Humans; Leucovorin; Lymph Nodes; Lymphoma, T-Cell, Peripheral; Male; Mycosis Fungoides; Premedication; Skin; Tomography, X-Ray Computed

2013
Pralatrexate in Combination with Bortezomib for Relapsed or Refractory Peripheral T Cell Lymphoma in 5 Elderly Patients.
    Journal of Korean medical science, 2016, Volume: 31, Issue:7

    Topics: Aged; Aminopterin; Antineoplastic Agents; Bortezomib; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lymphoma, T-Cell, Peripheral; Male; Neoplasm Recurrence, Local; Neutropenia; Positron Emission Tomography Computed Tomography

2016
The survival outcome of patients with relapsed/refractory peripheral T-cell lymphoma-not otherwise specified and angioimmunoblastic T-cell lymphoma.
    British journal of haematology, 2017, Volume: 176, Issue:5

    Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Depsipeptides; Disease-Free Survival; Female; Humans; Immunoblastic Lymphadenopathy; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Salvage Therapy; Stem Cell Transplantation; Survival Rate; Young Adult

2017
FDA approves pralatrexate for treatment of rare lymphoma.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Nov-01, Volume: 66, Issue:21

    Topics: Aminopterin; Antineoplastic Agents; Drug Approval; Folic Acid Antagonists; Humans; Lymphoma, T-Cell, Peripheral; United States; United States Food and Drug Administration

2009
Pralatrexate (Folotyn) for peripheral T-cell lymphoma.
    The Medical letter on drugs and therapeutics, 2010, Jul-12, Volume: 52, Issue:1342

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Humans; Lymphoma, T-Cell, Peripheral

2010
Hematology: relapsed and refractory PTCL--into the therapeutic abyss.
    Nature reviews. Clinical oncology, 2011, Volume: 8, Issue:6

    Topics: Aminopterin; Antineoplastic Agents; Drug Resistance, Neoplasm; Folic Acid Antagonists; Hematology; Humans; Lymphoma, T-Cell, Peripheral; Neoplasm Recurrence, Local; Salvage Therapy

2011