Page last updated: 2024-09-02

10-hydroxycarbamazepine and Aura

10-hydroxycarbamazepine has been researched along with Aura in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's9 (36.00)18.2507
2000's10 (40.00)29.6817
2010's2 (8.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Chen, Z; Dai, Q; Guan, Y; Huang, M; Li, R; Ren, R; Tang, S; Wang, X; Wen, D; Zhang, X; Zhou, L; Zhou, S1
Chen, X; Fang, S; Gong, Z; Ma, H; Qian, L; Wei, J; Xu, Z; Yan, Y; Yang, X; Zeng, S1
Cai, LX; Chen, CY; Cui, YM; Li, RR; Ma, LY; Sheng, XY; Wu, Y; Yao, HX; Zhou, Y; Zhu, SN1
Bartoli, A; Galimberti, CA; Gatti, G; Limido, G; Manni, R; Morini, R; Perucca, E; Strada, G; Tartara, A1
Baumann, RJ; DeGrauw, TJ; Fakhoury, TA; Grim, SA; Miles, MV; Ryan, MA; Strawsburg, RH; Tang, PH1
Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I1
Baumgartner, C; Caccia, S; Czech, T; Guiso, G; Janigro, D; Marchi, N; Novak, K; Pirker, S; Rizzi, M; Vezzani, A1
Bilo, L; Di Nocera, P; Fasiello, C; Italiano, D; Pisani, F; Ruosi, P; Striano, P; Striano, S1
Christensen, J; Sabers, A; Sidenius, P1
Hansen, SH; Linnet, K; Sabers, A; Simonsen, KW; Steentoft, A1
Artesi, C; Di Perri, R; Fazio, A; Oteri, G; Perucca, E; Pisani, F; Xiao, B1
Meinardi, H; Van Parys, JA1
Schwabe, S1
Perucca, E1
May, TW; Rambeck, B; Sälke-Kellermann, A1
Frey, HH; Schicht, S; Wigger, D1
Bialer, M; Volosov, A; Yagen, B1
Christensen, J; Dam, M; Højskov, CS; Poulsen, JH1
Jouppila, P; Myllynen, P; Pienimäki, P; Vähäkangas, K1
Boas, J; Dam, M; Flesch, G; Jensen, PK; Jórgensen, L; Mogensen, PH; Vesterager, A1
Elyas, AA; Goldberg, VD; Patsalos, PN1
Paar, WD; von Unruh, GE1
Bayraktar, E; Eltokhi, A; Hedrich, UBS; Lauxmann, S; Lerche, H; Liu, Y; Lyu, H; Sara, Y; Sonnenberg, L; Wuttke, TV1
Bak, LK; Jakobsen, E; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH1
Albani, F; Balboni, M; Baruzzi, A; Callegati, E; Candela, C; Contin, M; Riva, R1

Reviews

1 review(s) available for 10-hydroxycarbamazepine and Aura

ArticleYear
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin

1996

Trials

4 trial(s) available for 10-hydroxycarbamazepine and Aura

ArticleYear
Saliva and Plasma Monohydroxycarbamazepine Concentrations in Pediatric Patients With Epilepsy.
    Therapeutic drug monitoring, 2016, Volume: 38, Issue:3

    Topics: Adolescent; Anticonvulsants; Asian People; Carbamazepine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Epilepsy; Female; Humans; Infant; Linear Models; Male; Oxcarbazepine; Prospective Studies; Saliva

2016
The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:4

    Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Oxcarbazepine; Phenobarbital; Valproic Acid

1993
Effects of the antidepressant drug viloxazine on oxcarbazepine and its hydroxylated metabolites in patients with epilepsy.
    Acta neurologica Scandinavica, 1994, Volume: 90, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Epilepsies, Partial; Epilepsy; Epilepsy, Complex Partial; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxcarbazepine; Viloxazine

1994
Gas chromatographic/mass spectrometric assays for oxcarbazepine and its main metabolites, 10-hydroxy-carbazepine and carbazepine-10,11-trans-diol.
    Biomedical & environmental mass spectrometry, 1986, Volume: 13, Issue:12

    Topics: Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Epilepsy; Gas Chromatography-Mass Spectrometry; Humans; Oxcarbazepine

1986

Other Studies

20 other study(ies) available for 10-hydroxycarbamazepine and Aura

ArticleYear
LC-MS/MS quantification of levetiracetam, lamotrigine and 10-hydroxycarbazepine in TDM of epileptic patients.
    Biomedical chromatography : BMC, 2022, Volume: 36, Issue:8

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Monitoring; Epilepsy; Humans; Lamotrigine; Levetiracetam; Reproducibility of Results; Tandem Mass Spectrometry

2022
Comparison of oxcarbazepine efficacy and MHD concentrations relative to age and BMI: Associations among ABCB1, ABCC2, UGT2B7, and SCN2A polymorphisms.
    Medicine, 2019, Volume: 98, Issue:12

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Asian People; ATP Binding Cassette Transporter, Subfamily B; Body Mass Index; Carbamazepine; Child; Child, Preschool; China; Epilepsy; Female; Genotype; Glucuronosyltransferase; Humans; Infant; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; NAV1.2 Voltage-Gated Sodium Channel; Oxcarbazepine; Polymorphism, Single Nucleotide; Young Adult

2019
Feasibility and limitations of oxcarbazepine monitoring using salivary monohydroxycarbamazepine (MHD).
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Feasibility Studies; Female; Humans; Male; Middle Aged; Oxcarbazepine; Saliva

2004
Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine.
    Neuroscience letters, 2005, Dec-16, Volume: 390, Issue:1

    Topics: Animals; Anticonvulsants; Biomarkers; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Kinetics; Male; Metabolic Clearance Rate; Microdialysis; Pharmacokinetics; Rats; Rats, Wistar; Serotonin; Treatment Outcome

2005
A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine.
    Epilepsia, 2005, Volume: 46, Issue:10

    Topics: Adult; Aged; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Child; Drug Resistance; Drug Resistance, Multiple; Epilepsy; Female; Humans; In Vitro Techniques; Male; Oxcarbazepine; Pilot Projects; RNA, Messenger

2005
Relationship between serum mono-hydroxy-carbazepine concentrations and adverse effects in patients with epilepsy on high-dose oxcarbazepine therapy.
    Epilepsy research, 2006, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine

2006
Oxcarbazepine concentrations during pregnancy: a retrospective study in patients with epilepsy.
    Neurology, 2006, Oct-24, Volume: 67, Issue:8

    Topics: Analysis of Variance; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Osmolar Concentration; Oxcarbazepine; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Retrospective Studies

2006
An oxcarbazepine-related fatality with an overview of 26 oxcarbazepine postmortem cases.
    Forensic science international, 2008, May-20, Volume: 177, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Forensic Toxicology; Gastrointestinal Contents; Humans; Liver; Male; Middle Aged; Muscle, Skeletal; Oxcarbazepine; Vitreous Body

2008
Survey of 260 epileptic patients treated with oxcarbazepine (Trileptal) on a named-patient basis.
    Epilepsy research, 1994, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Netherlands; Oxcarbazepine; Product Surveillance, Postmarketing; Treatment Outcome

1994
Oxcarbazepine: clinical development program.
    Epilepsia, 1994, Volume: 35 Suppl 5

    Topics: Aged; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Approval; Drugs, Investigational; Enzyme Induction; Epilepsy; Humans; Liver; Oxcarbazepine; United States; United States Food and Drug Administration

1994
Fluctuations of 10-hydroxy-carbazepine during the day in epileptic patients.
    Acta neurologica Scandinavica, 1996, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Time Factors; Valproic Acid

1996
Pharmacokinetics of oxcarbazepine in the dog.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:1

    Topics: Administration, Oral; Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Dogs; Epilepsy; Female; Half-Life; Jejunum; Male; Oxcarbazepine; Protein Binding; Statistics as Topic

1996
Comparative stereoselective pharmacokinetic analysis of 10-hydroxycarbazepine after oral administration of its individual enantiomers and the racemic mixture to dogs.
    Epilepsia, 2000, Volume: 41, Issue:9

    Topics: Administration, Oral; Animals; Anticonvulsants; Area Under Curve; Carbamazepine; Cross-Over Studies; Dogs; Drug Design; Epilepsy; Glucuronides; Humans; Oxcarbazepine; Stereoisomerism

2000
Plasma concentration of topiramate correlates with cerebrospinal fluid concentration.
    Therapeutic drug monitoring, 2001, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Blood-Brain Barrier; Brain; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Prospective Studies; Topiramate; Triazines

2001
Transplacental passage of oxcarbazepine and its metabolites in vivo.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Oxcarbazepine; Placenta; Pregnancy; Pregnancy Complications

2001
Effects of dextropropoxyphene on the steady-state kinetics of oxcarbazepine and its metabolites.
    Acta neurologica Scandinavica, 1992, Volume: 85, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Trigeminal Neuralgia

1992
Simple and rapid micro-analytical high-performance liquid chromatographic technique for the assay of oxcarbazepine and its primary active metabolite 10-hydroxycarbazepine.
    Journal of chromatography, 1990, Jun-29, Volume: 528, Issue:2

    Topics: Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Microchemistry; Oxcarbazepine

1990
In vitro effects of eslicarbazepine (S-licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders.
    British journal of pharmacology, 2023, Volume: 180, Issue:8

    Topics: Animals; Dibenzazepines; Epilepsy; Mice; Mutation; NAV1.6 Voltage-Gated Sodium Channel

2023
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.
    European journal of pharmacology, 2020, Nov-05, Volume: 886

    Topics: Adenylyl Cyclases; Anticonvulsants; Calcium Signaling; Carbamazepine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dibenzazepines; Epilepsy; HEK293 Cells; Humans; Oxcarbazepine; Seizures; Signal Transduction; Treatment Outcome

2020
Simultaneous liquid chromatographic determination of lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in plasma of patients with epilepsy.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Dec-15, Volume: 828, Issue:1-2

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Drug Monitoring; Epilepsy; Felbamate; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Spectrophotometry, Ultraviolet; Triazines

2005