10-hydroxycarbamazepine has been researched along with Absence Seizure in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Alves, PC; Benes, J; Cunha, RA; Figueiredo, AA; Freitas, AP; Garrett, J; Learmonth, DA; Parada, A; Soares-da-Silva, P | 1 |
| Alexandre Junior, V; Antunes, NJ; Coelho, EB; Della Pasqua, O; Lanchote, VL; Takayanagui, OM; Tozatto, E; van Dijkman, SC; van Hasselt, JGC; Wichert-Ana, L | 1 |
| Clinckers, R; Danhof, M; Della Pasqua, O; Ebinger, G; Michotte, Y; Smolders, I; Voskuyl, RA | 1 |
| Feldmann, KF; McLean, MJ; Portet, C; Schmutz, M; Wamil, AW | 1 |
| Brugger, F; Gentsch, C; McLean, MJ; Olpe, HR; Schmutz, M | 1 |
| Bak, LK; Jakobsen, E; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH | 1 |
| Almeida, L; Elger, C; Falcão, A; Halász, P; Perucca, E; Soares-da-Silva, P | 1 |
2 trial(s) available for 10-hydroxycarbamazepine and Absence Seizure
| Article | Year |
|---|---|
Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects.
Topics: Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Carbamazepine; Cross-Over Studies; Female; Healthy Volunteers; Humans; Male; Oxcarbazepine; Seizures; Stereoisomerism; Verapamil; Young Adult | 2017 |
Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Dose-Response Relationship, Drug; Female; Humans; International Cooperation; Male; Middle Aged; Oxcarbazepine; Seizures; Tandem Mass Spectrometry; Time Factors; Young Adult | 2011 |
5 other study(ies) available for 10-hydroxycarbamazepine and Absence Seizure
| Article | Year |
|---|---|
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
Topics: Amides; Animals; Anticonvulsants; Azepines; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; In Vitro Techniques; Ion Channel Gating; Motor Activity; Prodrugs; Rats; Seizures; Sodium; Stereoisomerism; Structure-Activity Relationship; Synaptosomes | 1999 |
Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain.
Topics: Animals; Anticonvulsants; Biological Transport; Carbamazepine; Chromatography, Liquid; Dose-Response Relationship, Drug; Hippocampus; Male; Microdialysis; Models, Biological; Nonlinear Dynamics; Rats; Rats, Wistar; Seizures; Tissue Distribution | 2008 |
Effects of oxcarbazepine and 10-hydroxycarbamazepine on action potential firing and generalized seizures.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Cells, Cultured; Male; Mice; Oxcarbazepine; Rats; Seizures; Sodium; Spinal Cord | 1994 |
Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Mice; Oxcarbazepine; Pentylenetetrazole; Potassium Channels; Rats; Receptors, Neurotransmitter; Seizures; Sodium Channels | 1994 |
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.
Topics: Adenylyl Cyclases; Anticonvulsants; Calcium Signaling; Carbamazepine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dibenzazepines; Epilepsy; HEK293 Cells; Humans; Oxcarbazepine; Seizures; Signal Transduction; Treatment Outcome | 2020 |