10-hydroxycamptothecin has been researched along with Neoplasms in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 25 (73.53) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Choe, YH; Greenwald, RB; Wu, D | 1 |
| Chen, CS; Chern, JW; Leu, YL; Wu, YJ | 1 |
| Chen, XG; Chern, JW; Guo, QL; He, XG; Huang, CH; Li, TK; Li, ZY; Wang, XJ; Yang, Q; You, QD | 1 |
| Bi, CW; Du, NN; Jiang, JD; Li, X; Li, YB; Ren, KH; Shao, RG; Song, DQ; Wang, YX; Zhao, WL | 1 |
| He, GX; Kong, SL; Mo, DL; Pan, CX; Su, GF; Wang, LY; Wei, K; Yuan, JM; Zhu, HM | 1 |
| Hua, S; Huang, R; Huang, X; Ji, M; Jin, L; Wang, H; Zhang, B | 1 |
| Cong, H; Hu, H; Jing, X; Meng, Q; Shen, Y; Sun, Y; Yu, B; Zhou, L; Zhu, Y | 1 |
| Fan, G; Jia, S; Lin, K; Shi, J; Yu, S; Yuan, J; Zhang, Y; Zhou, Q | 1 |
| Chen, P; Jian, S; Li, F; Li, H; Li, J; Liang, S; Liu, Z; Sun, X; Zeng, Y; Zhang, P; Zhang, Q | 1 |
| Fan, Z; Fu, X; Hai, J; He, S; Hou, Z; Shi, D; Yang, Y; Yin, W; Zhang, D | 1 |
| Du, Y; Fu, Z; He, R; Ismail, M; Li, X; Ling, L; Yao, C; Zhang, W | 1 |
| Bao, Y; Guo, L; Ji, F; Li, Y; Tang, Q; Wang, J | 1 |
| Cheng, A; Hou, Z; Jin, X; Wu, S; Xie, W; Yang, L; Yang, X | 1 |
| Dong, Z; Guo, Y; Han, M; Wang, T; Wang, X; Wang, Y; Zhao, S | 1 |
| Ahmad, I; Eltahan, AS; Kaleem, QM; Li, C; Liang, XJ; Mozhi, A; Tuguntaev, RG; Wang, C; Yang, R | 1 |
| Dong, Z; Guo, Y; Han, M; Qiu, H; Wang, T; Wang, X; Wang, Y | 1 |
| Fan, Z; Hou, Z; Jiang, B; Li, Y; Su, G; Tian, H; Wang, F; Ye, S; Zhang, Y; Zhu, Q | 1 |
| Jie, J; Liu, Z; Tian, B; Yang, Y; Zhang, X; Zhou, M | 1 |
| Hao, X; Jie, J; Yang, Y; Yu, C; Zhang, X; Zhou, M | 1 |
| Chu, L; Ding, D; Kong, D; Liu, J; Xu, H; Yang, C; Yang, Z; Zhang, Y | 1 |
| Tian, B; Yu, C; Zhang, X; Zhou, M | 1 |
| Guo, N; Jiang, D; Teng, YO; Wang, L; You, X; Yu, P | 1 |
| Dai, Z; Jing, L; Shao, S; Wang, Y; Yang, Y; Yue, X | 1 |
| Chen, B; Feng, J; Jiang, Y; Liu, G; Wang, H; Xie, Q | 1 |
| Ci, T; Cui, S; Ding, J; Liu, R; Shen, Y; Yu, L | 1 |
| Cai, Y; Dai, L; Gao, J; Lin, M; Liu, J; Ren, C; Shen, H; Shi, Y; Yang, Z; Zhan, J | 1 |
| Cai, XM; Liu, MZ; Xie, HL; Zha, XL | 1 |
| Gan, L; Gan, Y; Gao, Y; Zhang, XX; Zhu, CL | 1 |
| Li, X; Liu, C; Luo, X; Wang, H; Xie, C; Yan, S | 1 |
| An, F; Diao, X; Hao, X; Li, W; Liu, Z; Wang, C; Yang, Y; Zhang, X | 1 |
| Li, P; Lin, Y; Ran, H; Ren, J; Tan, J; Wang, Z; Zhang, Q; Zheng, Y | 1 |
| Cao, J; Cui, S; Gu, Y; Qian, Z; Zhu, H | 1 |
| Chen, Q; Guan, ZZ; He, YJ; Hu, XH; Huang, HQ; Jiang, WQ; Li, YH; Lin, XB; Lin, Z; Liu, KF; Shen, WX | 1 |
| Guo, R; Jiang, X; Li, Y; Liu, B; Wang, Q; Yang, C; Yang, M; Zhang, L | 1 |
1 trial(s) available for 10-hydroxycamptothecin and Neoplasms
| Article | Year |
|---|---|
[Preliminary study of lyophilized 10-hydroxycamptothecin in advanced or recurrent malignancies].
Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Humans; Male; Middle Aged; Neoplasms; Recurrence; Treatment Outcome | 2003 |
33 other study(ies) available for 10-hydroxycamptothecin and Neoplasms
| Article | Year |
|---|---|
Selective phenolic acylation of 10-hydroxycamptothecin using poly (ethylene glycol) carboxylic acid.
Topics: Acylation; Animals; Antineoplastic Agents; Camptothecin; Carboxylic Acids; Hydrogen Bonding; Hydroxyquinolines; Indicators and Reagents; Leukemia P388; Magnetic Resonance Spectroscopy; Neoplasms; Polyethylene Glycols; Rats; Tumor Cells, Cultured | 2003 |
Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy.
Topics: Antibodies, Neoplasm; Antineoplastic Agents; Binding, Competitive; Camptothecin; Catalysis; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Escherichia coli; Glucuronidase; Glucuronides; Humans; Kinetics; Models, Molecular; Molecular Structure; Neoplasms; Phenyl Ethers; Prodrugs; Structure-Activity Relationship | 2008 |
Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; Drug Discovery; Enzyme Inhibitors; Female; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Conformation; Naphthyridines; Neoplasms; Quinolones; Topoisomerase I Inhibitors; Transplantation, Heterologous | 2009 |
Synthesis, structure-activity relationship and biological evaluation of anticancer activity for novel N-substituted sophoridinic acid derivatives.
Topics: Alkaloids; Antineoplastic Agents; Cell Death; Chemistry Techniques, Synthetic; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Quinolizines; Stereoisomerism; Structure-Activity Relationship | 2011 |
Synthesis and antitumor evaluation of 2,3-diarylbenzofuran derivatives on HeLa cells.
Topics: Antineoplastic Agents; Benzofurans; Cell Cycle; Cell Proliferation; Cell Survival; HeLa Cells; Humans; Models, Molecular; Neoplasms | 2017 |
Glycyrrhetinic acid derivatives containing aminophosphonate ester species as multidrug resistance reversers that block the NF-κB pathway and cell proliferation.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Humans; Molecular Docking Simulation; Neoplasms; NF-kappa B; Signal Transduction | 2018 |
A modular ROS-responsive platform co-delivered by 10-hydroxycamptothecin and dexamethasone for cancer treatment.
Topics: Camptothecin; Cell Line, Tumor; Dexamethasone; Drug Delivery Systems; Drug Liberation; Micelles; Nanoparticles; Neoplasms; Reactive Oxygen Species | 2021 |
Specific Modification with TPGS and Drug Loading of Cyclodextrin Polyrotaxanes and the Enhanced Antitumor Activity Study in Vitro and in Vivo.
Topics: Animals; Anticarcinogenic Agents; Camptothecin; Cell Line, Tumor; Cellulose; Cyclodextrins; Drug Delivery Systems; Humans; Mice; Nanoparticles; Neoplasms; Rotaxanes; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Drug-Bearing Peptide-Based Nanospheres for the Inhibition of Metastasis and Growth of Cancer.
Topics: A549 Cells; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; HeLa Cells; Hep G2 Cells; Humans; Melanoma, Experimental; Nanospheres; Nanostructures; Neoplasms; Peptides; Small Molecule Libraries | 2020 |
Shuttle-Shape Carrier-Free Platinum-Coordinated Nanoreactors with O
Topics: Animals; Antineoplastic Agents; Camptothecin; Catalysis; Cell Line, Tumor; Drug Carriers; Drug Liberation; Female; Humans; Hydrogen Peroxide; Light; Methylene Blue; Mice, Inbred BALB C; Nanostructures; Neoplasms; Oxygen; Photosensitizing Agents; Photothermal Therapy; Platinum; Polymers; Porosity; Singlet Oxygen; Theranostic Nanomedicine; Tumor Hypoxia | 2021 |
Dual 7-ethyl-10-hydroxycamptothecin conjugated phospholipid prodrug assembled liposomes with in vitro anticancer effects.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; Liposomes; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phospholipids; Prodrugs; Solubility; Succinic Acid | 2017 |
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Synergism; Female; Humans; Membrane Potential, Mitochondrial; Mice, Nude; Neoplasms; Quercetin; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Dual-drug loaded nanoneedles with targeting property for efficient cancer therapy.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; Drug Carriers; Drug Liberation; Drug Synergism; HeLa Cells; Humans; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Neoplasms; Polyethylene Glycols; Polyglactin 910; Tissue Distribution; Transplantation, Heterologous | 2017 |
Amphiphilic Hybrid Dendritic-Linear Molecules as Nanocarriers for Shape-Dependent Antitumor Drug Delivery.
Topics: Amines; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Nanospheres; Nanotubes; Neoplasms; Particle Size; Polyethylene Glycols; Rats; Surface-Active Agents; Treatment Outcome | 2018 |
Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy.
Topics: A549 Cells; Apoptosis; Camptothecin; Cell Nucleus; DNA Topoisomerases, Type I; Drug Carriers; Drug Synergism; Hep G2 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Nanoparticles; Neoplasms; Neuropilin-1; Peptides; Polymers; Reactive Oxygen Species; Topoisomerase I Inhibitors; Vitamin E | 2018 |
Hydroxycamptothecin nanoparticles based on poly/oligo (ethylene glycol): Architecture effects of nanocarriers on antitumor efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Drug Storage; Ethylene Glycol; Humans; Injections, Intravenous; Mice; Mice, Inbred BALB C; Molecular Conformation; Nanoparticles; Neoplasms; Particle Size; Rats; Tissue Distribution | 2019 |
Light/pH-Triggered Biomimetic Red Blood Cell Membranes Camouflaged Small Molecular Drug Assemblies for Imaging-Guided Combinational Chemo-Photothermal Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomimetics; Camptothecin; Cell Membrane; Erythrocytes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Indocyanine Green; Infrared Rays; Male; Mice; Mice, Nude; Nanoparticles; Neoplasms; Phototherapy; Rats; Rats, Sprague-Dawley | 2019 |
Carrier-free functionalized multidrug nanorods for synergistic cancer therapy.
Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; KB Cells; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotubes; Neoplasms; Paclitaxel | 2013 |
Smart nanorods for highly effective cancer theranostic applications.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds, Heterocyclic; Camptothecin; Cell Line, Tumor; Disulfides; Drug Carriers; Half-Life; HeLa Cells; Humans; Magnetic Resonance Imaging; Mice, Inbred BALB C; Nanotubes; Neoplasms; Phototherapy; Polyethylene Glycols; Polymers; Radiography; Tissue Distribution | 2014 |
Self-assembling peptide of D-amino acids boosts selectivity and antitumor efficacy of 10-hydroxycamptothecin.
Topics: Amino Acids; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Peptides | 2014 |
The aspect ratio effect of drug nanocrystals on cellular internalization efficiency, uptake mechanisms, and in vitro and in vivo anticancer efficiencies.
Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Carriers; Drug Screening Assays, Antitumor; Female; Humans; Liver; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Nanomedicine; Nanoparticles; Neoplasm Transplantation; Neoplasms; Polyethylene Glycols | 2015 |
Synthesis and Biological Evaluation of Novel Water-Soluble Poly-(ethylene glycol)-10-hydroxycamptothecin Conjugates.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Hep G2 Cells; HT29 Cells; Humans; Neoplasms; Polyethylene Glycols; Solubility | 2015 |
Hyaluronic Acid Modified Hollow Prussian Blue Nanoparticles Loading 10-hydroxycamptothecin for Targeting Thermochemotherapy of Cancer.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Drug Carriers; Drug Therapy; Ferrocyanides; HeLa Cells; Humans; Hyperthermia, Induced; Nanoparticles; Neoplasms | 2016 |
In vitro and in vivo anti-tumor efficacy of 10-hydroxycamptothecin polymorphic nanoparticle dispersions: shape- and polymorph-dependent cytotoxicity and delivery of 10-hydroxycamptothecin to cancer cells.
Topics: Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Humans; Nanoparticles; Neoplasms; Particle Size; Solubility; Tissue Distribution | 2016 |
Achieving High Drug Loading and Sustained Release of Hydrophobic Drugs in Hydrogels through In Situ Crystallization.
Topics: Camptothecin; Crystallization; Delayed-Action Preparations; Drug Delivery Systems; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Neoplasms; Polyethylene Glycols | 2017 |
Supramolecular "Trojan Horse" for Nuclear Delivery of Dual Anticancer Drugs.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Macromolecular Substances; Mice; Molecular Structure; Nanomedicine; Neoplasms | 2017 |
Inhibition of cell growth and invasion by epidermal growth factor-targeted phagemid particles carrying siRNA against focal adhesion kinase in the presence of hydroxycamptothecin.
Topics: Antineoplastic Agents, Phytogenic; Bacteriophages; Base Sequence; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Combined Modality Therapy; Epidermal Growth Factor; Focal Adhesion Protein-Tyrosine Kinases; Genetic Vectors; Humans; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasms; RNA Interference; RNA, Small Interfering | 2008 |
Lipid-polymer composite microspheres for colon-specific drug delivery prepared using an ultrasonic spray freeze-drying technique.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Colon; Drug Delivery Systems; Excipients; Fatty Acids; Freeze Drying; Humans; Microspheres; Neoplasms; Particle Size; Polymethacrylic Acids; Solubility; Ultrasonics | 2011 |
Antitumor activities of emulsion electrospun fibers with core loading of hydroxycamptothecin via intratumoral implantation.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Emulsions; Humans; Lactates; Mice; Neoplasm Transplantation; Neoplasms; Polyethylene Glycols; Tumor Burden | 2012 |
Carrier-free, functionalized drug nanoparticles for targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Maleic Anhydrides; Nanoparticles; Neoplasms; Polyethylene Glycols | 2012 |
Ultrasound triggered drug release from 10-hydroxycamptothecin-loaded phospholipid microbubbles for targeted tumor therapy in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Male; Mice; Microbubbles; Neoplasms; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Sonication; Tumor Burden | 2012 |
Enhanced tumor targeting and antitumor efficacy via hydroxycamptothecin-encapsulated folate-modified N-succinyl-N'-octyl chitosan micelles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Neoplasms; Rats | 2013 |
10-Hydroxycamptothecin loaded nanoparticles: preparation and antitumor activity in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Humans; Mice; Mice, Inbred ICR; Nanoparticles; Neoplasms; Xenograft Model Antitumor Assays | 2007 |