10-hydroxycamptothecin has been researched along with Lung Neoplasms in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Boehm, JC; Caranfa, MJ; Faucette, LF; Gallagher, G; Hecht, SM; Holden, KG; Jakas, DR; Johnson, RK; Kingsbury, WD; McCabe, FL | 1 |
| Bu, XZ; Gu, LQ; Shen, YD; Tian, YX | 1 |
| Chen, SB; Gu, LQ; Huang, SL; Huang, ZH; Huang, ZS; Li, D; Ou, JB; Ou, TM; Shen, LL; Tan, JH; Wu, WB | 1 |
| Gao, J; Guo, L; Li, X; Liu, Z; Teng, Y; Xie, W; Xu, Y; Yu, P; Zhao, L | 1 |
| Guo, X; Jing, Y; Ming, Y; Xiong, X; Yang, G; Zhao, J; Zhou, S | 1 |
| Hong, T; Li, J; Liu, W; Luo, J; Tong, L; Wang, F; Yan, L; Yang, X; Zhou, Y | 1 |
| Chen, H; Du, W; Li, G; Li, M; Liang, X; Yang, W; Zhang, C; Zhang, W | 1 |
| Gan, L; Gan, Y; Nie, S; Pan, W; Zhang, X | 1 |
| Fang, Y; Hu, W; Lou, C; Zhang, C | 1 |
| Chen, YH; Ding, L; Huo, S; Lu, Q; Renegar, R; Wang, X; Zhang, G | 1 |
| Colson, YL; Grinstaff, MW; Wolinsky, JB; Yohe, ST | 1 |
| Chen, SZ; Shang, BY; Shang, Y; Zhen, YS | 1 |
| Cai, X; Guo, YW; Lin, F; Sun, YJ; Tang, XC; Yao, Y; Zhao, H | 2 |
| Guo, W; Qiu, WL; Yu, Y; Zhou, XJ | 1 |
15 other study(ies) available for 10-hydroxycamptothecin and Lung Neoplasms
| Article | Year |
|---|---|
Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cattle; Cell Line; Colonic Neoplasms; DNA, Superhelical; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia L1210; Lung Neoplasms; Melanoma, Experimental; Mice; Molecular Structure; Plasmids; Structure-Activity Relationship; Thymus Gland; Topoisomerase I Inhibitors; Transplantation, Heterologous | 1991 |
Natural tanshinone-like heterocyclic-fused ortho-quinones from regioselective Diels-Alder reaction: synthesis and cytotoxicity evaluation.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Furans; Humans; Lung Neoplasms; Models, Molecular; Molecular Structure; Naphthoquinones; Nasopharyngeal Neoplasms; Stereoisomerism; Structure-Activity Relationship | 2009 |
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Survival; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Etoposide; Humans; Inhibitory Concentration 50; Lung Neoplasms; Naphthoquinones; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Plasmids; Pyrans; Quinones; Sesquiterpenes; Structure-Activity Relationship; Telomerase; Topoisomerase Inhibitors | 2011 |
Development of 10-Hydroxycamptothecin-crizotinib conjugate based on the synergistic effect on lung cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Crizotinib; ErbB Receptors; Humans; Lung Neoplasms | 2023 |
A Multifunctional Micellar Nanoplatform with pH-Triggered Cell Penetration and Nuclear Targeting for Effective Cancer Therapy and Inhibition to Lung Metastasis.
Topics: A549 Cells; Animals; Camptothecin; Delayed-Action Preparations; Drug Carriers; Female; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Neoplasm Metastasis | 2018 |
Astragalus polysaccharide combined with 10-hydroxycamptothecin inhibits metastasis in non-small cell lung carcinoma cell lines via the MAP4K3/mTOR signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Astragalus Plant; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression; Humans; Lung Neoplasms; Mitochondria; Polysaccharides; Protein Serine-Threonine Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Tissue Distribution and Anti-Lung Cancer Effect of 10-Hydroxycamptothecin Combined with Platycodonis Radix and Glycyrrhizae Radix ET Rhizoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Lewis Lung; Chromatography, Liquid; Cytokines; Disease Models, Animal; Drug Monitoring; Drugs, Chinese Herbal; Glycyrrhiza; Lung Neoplasms; Male; Mice; Plant Roots; Rhizome; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tissue Distribution; Xenograft Model Antitumor Assays | 2019 |
PEGylated nanostructured lipid carriers loaded with 10-hydroxycamptothecin: an efficient carrier with enhanced anti-tumour effects against lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Stability; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Weight; Nanostructures; Particle Size; Polyethylene Glycols; Solubility; Stearates; Tissue Distribution | 2008 |
Anticancer properties of 10-hydroxycamptothecin in a murine melanoma pulmonary metastasis model in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL | 2011 |
Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cadherins; Camptothecin; Caspase 8; Cell Line, Tumor; Cell Proliferation; Cell Survival; Claudins; Drug Delivery Systems; Ferrous Compounds; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Potentials; Membrane Proteins; Nanoparticles; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Tight Junctions; X-Ray Diffraction; Zonula Occludens-1 Protein | 2011 |
Functionalized hydrophobic poly(glycerol-co-ε-caprolactone) depots for controlled drug release.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lung Neoplasms; Magnetic Resonance Spectroscopy; Particle Size; Polyesters; Surface Properties | 2012 |
[Lidamycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs].
Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; Enediynes; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluorouracil; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays | 2011 |
[Short-term effects of chemotherapy with combination of hydroxycamptothecine and oxaliplatin in the treatment of advanced digestive tract cancers].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Female; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Stomach Neoplasms; Treatment Outcome | 2004 |
[Experimental study of hydroxycamptothecine and theprubicine in the treatment of adenoid cystic carcinoma lung metastases].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Adenoid Cystic; Epirubicin; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Salivary Gland Neoplasms; Tumor Cells, Cultured | 2006 |
[Short-term effects of chemotherapy combined with hydroxycamptothecine and oxaliplatin in treatment of recurrent and metastatic colorectal cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Survival Rate | 2006 |