Page last updated: 2024-08-26

10-hydroxycamptothecin and Hepatocellular Carcinoma

10-hydroxycamptothecin has been researched along with Hepatocellular Carcinoma in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's8 (47.06)29.6817
2010's7 (41.18)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Chen, J; Du, D; Liu, C; Wu, Y1
Chen, X; Ding, J; Li, D; Li, J; Liu, T; Xu, W; Zhang, YS1
Deng, Y; Ge, Y; Meng, L; Yu, X; Zhang, Y; Zhao, X; Zu, Y1
Cao, Y; Chen, D; Chen, S; He, H; Huang, X; Lei, S; Liu, M; Luo, S; Mukerabigwi, JF; Wen, Z; Zhang, Y1
Gong, T; Liu, J; Ren, K; Shi, SJ; Sun, X; Wei, W; Zhang, XN; Zhang, ZR; Zhao, D1
Huang, A; Niu, J; Ping, Q; Sang, X; Su, Z; Sun, M; Xiao, Y; You, W; Yuan, D1
Feng, G; Liang, B; Liang, H; Qian, J; Wang, Y; Zhao, H; Zheng, C1
Jia, G; Li, X; Luo, X; Song, H; Xu, G; Yan, S; Yang, S1
Fu, ZD; Li, DZ; Liu, HY; Pan, XD; Wang, CY; Wu, S1
Cai, W; Chen, JP; Li, XY; Wu, XY; Yao, DF; Yu, JW; Yu, ZJ; Yuan, HX; Yuan, Y1
Fu, YR; Qiu, ZY; Yan, YR1
Gao, K; Li, X; Pan, J1
Yu, ZJ1
Xu, B; Zhang, XW1
Jiang, JF; Xu, B; Zhang, XW1
Liu, J; Xu, B; Zhou, JJ1
Xu, B; Zhang, X; Zhou, Y1

Trials

1 trial(s) available for 10-hydroxycamptothecin and Hepatocellular Carcinoma

ArticleYear
Evaluation of HCPTd1,d14-double passaged intervening chemotherapy protocol for hepatocellular carcinoma.
    World journal of gastroenterology, 2005, Sep-07, Volume: 11, Issue:33

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Male; Middle Aged; Portal Vein; Treatment Outcome

2005

Other Studies

16 other study(ies) available for 10-hydroxycamptothecin and Hepatocellular Carcinoma

ArticleYear
Preparation of PLGA microspheres loaded with 10-hydroxycamptothecin and arsenic trioxide and their treatment for rabbit hepatocellular carcinoma.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2021, Volume: 165, Issue:1

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Camptothecin; Carcinoma, Hepatocellular; Disease Models, Animal; Liver Neoplasms; Microspheres; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits

2021
Locally Deployable Nanofiber Patch for Sequential Drug Delivery in Treatment of Primary and Advanced Orthotopic Hepatomas.
    ACS nano, 2018, 07-24, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Implants; Female; Liver Neoplasms; Mice, Inbred BALB C; Nanofibers; Polyphenols

2018
Preparation of 10-hydroxycamptothecin-loaded glycyrrhizic acid-conjugated bovine serum albumin nanoparticles for hepatocellular carcinoma-targeted drug delivery.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Drug Carriers; Glycyrrhizic Acid; Hemolysis; Humans; Liver Neoplasms; Nanoparticles; Particle Size; Rabbits; Serum Albumin, Bovine

2013
Intracellular delivery of 10-hydroxycamptothecin with targeted nanostructured lipid carriers against multidrug resistance.
    Journal of drug targeting, 2016, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Glucans; Hep G2 Cells; Humans; Lipids; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Particle Size; Soybean Oil; Xylans

2016
Lipid nanoparticles loaded with 10-hydroxycamptothecin-phospholipid complex developed for the treatment of hepatoma in clinical application.
    Journal of drug targeting, 2010, Volume: 18, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Hep G2 Cells; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Phospholipids; Tissue Distribution

2010
Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine.
    Molecular pharmaceutics, 2011, Oct-03, Volume: 8, Issue:5

    Topics: Animals; Antineoplastic Agents; Biological Transport; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemical Phenomena; Delayed-Action Preparations; Drug Carriers; Half-Life; Humans; Ligands; Lipids; Liver Neoplasms; Male; Nanostructures; Neoplasm Proteins; Octreotide; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin

2011
Hepatocellular necrosis, apoptosis, and proliferation after transcatheter arterial embolization or chemoembolization in a standardized rabbit model.
    Journal of vascular and interventional radiology : JVIR, 2011, Volume: 22, Issue:11

    Topics: Alanine Transaminase; Angiography, Digital Subtraction; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Aspartate Aminotransferases; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Chemoembolization, Therapeutic; Embolization, Therapeutic; Hepatic Artery; In Situ Nick-End Labeling; Iodized Oil; Ki-67 Antigen; Liver Function Tests; Liver Neoplasms, Experimental; Liver Regeneration; Magnetic Resonance Imaging; Necrosis; Polyvinyl Alcohol; Rabbits; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha

2011
Promoted antitumor activities of acid-labile electrospun fibers loaded with hydroxycamptothecin via intratumoral implantation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzaldehydes; Camptothecin; Carcinoma, Hepatocellular; Electrochemistry; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Lactates; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Molecular Weight; Polyethylene Glycols; Survival Rate; Tumor Microenvironment

2012
Synthesis and antitumor activity of A-ring modified hexacyclic analogues of camptothecin.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Irinotecan; Liver Neoplasms; Mice; Neoplasm Transplantation; Polycyclic Compounds

2005
[Effect of hydroxycamptothecin on apoptosis-inducing factor (AIF) expression and on AIF translocation in human hepatocellular cancer cell SMMC-7721].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2006, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Translocation, Genetic

2006
Gamma-pyranone derivatives and other constituents from Erigeron annuus.
    Die Pharmazie, 2006, Volume: 61, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Erigeron; Flavanones; HL-60 Cells; Humans; Magnetic Resonance Spectroscopy; Pyrones; Tumor Cells, Cultured

2006
[Chinese material medica combined with cisplatin and lipiodol through transcatheter arterial embolization in the treatment of primary hepatoma].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Cantharidin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Female; Hepatic Artery; Humans; Immunotherapy, Adoptive; Iodized Oil; Liver Neoplasms; Male; Middle Aged

1993
Differential regulation of P53, c-Myc, Bcl-2, Bax and AFP protein expression, and caspase activity during 10-hydroxycamptothecin-induced apoptosis in Hep G2 cells.
    Anti-cancer drugs, 2000, Volume: 11, Issue:9

    Topics: alpha-Fetoproteins; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Caspase 3; Caspases; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Differentiation-inducing action of 10-hydroxycamptothecin on human hepatoma Hep G2 cells.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Differentiation; Humans; Liver Neoplasms; Proliferating Cell Nuclear Antigen; Telomerase; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Relationship between lactone ring forms of HCPT and their antitumor activities.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Female; Humans; Lactones; Liver Neoplasms; Mice; Sarcoma 180; Tumor Cells, Cultured

2001
Differentiation of human hepatoma Hep G2 cells induced by 10-hydroxycamptothecin.
    Chinese medical journal, 2000, Volume: 113, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Differentiation; Humans

2000