10-hydroxycamptothecin has been researched along with Cancer of Liver in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Du, D; Liu, C; Wu, Y | 1 |
| Li, G; Zhao, L; Zhao, M | 1 |
| Huang, S; Li, M; Nie, X; Ren, D; Wang, Y; Wu, X; Yu, X | 1 |
| Chen, X; Ding, J; Li, D; Li, J; Liu, T; Xu, W; Zhang, YS | 1 |
| Deng, Y; Ge, Y; Meng, L; Yu, X; Zhang, Y; Zhao, X; Zu, Y | 1 |
| Cao, Y; Chen, D; Chen, S; He, H; Huang, X; Lei, S; Liu, M; Luo, S; Mukerabigwi, JF; Wen, Z; Zhang, Y | 1 |
| Bian, X; Ding, D; Hu, Y; Jia, Z; Jiang, X; Li, R; Li, X; Wu, W; Zhu, Z | 1 |
| Feng, G; Li, X; Liang, B; Liang, H; Qian, J; Wang, Y; Wu, H; Zhao, H; Zheng, C | 1 |
| Jiang, X; Wu, W | 1 |
| Huang, A; Niu, J; Ping, Q; Sang, X; Su, Z; Sun, M; Xiao, Y; You, W; Yuan, D | 1 |
| Jia, G; Li, X; Luo, X; Song, H; Xu, G; Yan, S; Yang, S | 1 |
| Li, YL; Qin, QL; Qu, X; Song, WG; Wu, C; Xu, YP | 1 |
| Cai, X; Guo, YW; Lin, F; Sun, YJ; Tang, XC; Yao, Y; Zhao, H | 2 |
| Fu, ZD; Li, DZ; Liu, HY; Pan, XD; Wang, CY; Wu, S | 1 |
| Cai, W; Chen, JP; Li, XY; Wu, XY; Yao, DF; Yu, JW; Yu, ZJ; Yuan, HX; Yuan, Y | 1 |
| Feng, LF; Lei, XY; Liao, DF; Tang, SS; Zhong, M; Zhu, BY | 1 |
| Fu, YR; Qiu, ZY; Yan, YR | 1 |
| Yu, ZJ | 1 |
| Xu, B; Zhang, XW | 1 |
| Jiang, JF; Xu, B; Zhang, XW | 1 |
| Liu, J; Xu, B; Zhou, JJ | 1 |
1 trial(s) available for 10-hydroxycamptothecin and Cancer of Liver
| Article | Year |
|---|---|
Evaluation of HCPTd1,d14-double passaged intervening chemotherapy protocol for hepatocellular carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Male; Middle Aged; Portal Vein; Treatment Outcome | 2005 |
21 other study(ies) available for 10-hydroxycamptothecin and Cancer of Liver
| Article | Year |
|---|---|
Preparation of PLGA microspheres loaded with 10-hydroxycamptothecin and arsenic trioxide and their treatment for rabbit hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Camptothecin; Carcinoma, Hepatocellular; Disease Models, Animal; Liver Neoplasms; Microspheres; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2021 |
Lysine-mediated hydroxyethyl starch-10-hydroxy camptothecin micelles for the treatment of liver cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hep G2 Cells; Humans; Hydroxyethyl Starch Derivatives; Liver Neoplasms; Lysine; Male; Mice; Mice, Nude; Micelles; Rats, Wistar; Tissue Distribution | 2020 |
Glycyrrhetinic Acid and TAT Peptide Modified Dual-functional Liposomes for Treatment of Hepatocellular Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Liposomes; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Peptide Fragments; Surface Properties; tat Gene Products, Human Immunodeficiency Virus; Tumor Cells, Cultured | 2020 |
Locally Deployable Nanofiber Patch for Sequential Drug Delivery in Treatment of Primary and Advanced Orthotopic Hepatomas.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Implants; Female; Liver Neoplasms; Mice, Inbred BALB C; Nanofibers; Polyphenols | 2018 |
Preparation of 10-hydroxycamptothecin-loaded glycyrrhizic acid-conjugated bovine serum albumin nanoparticles for hepatocellular carcinoma-targeted drug delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Drug Carriers; Glycyrrhizic Acid; Hemolysis; Humans; Liver Neoplasms; Nanoparticles; Particle Size; Rabbits; Serum Albumin, Bovine | 2013 |
Intracellular delivery of 10-hydroxycamptothecin with targeted nanostructured lipid carriers against multidrug resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Glucans; Hep G2 Cells; Humans; Lipids; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Particle Size; Soybean Oil; Xylans | 2016 |
Covalently combining carbon nanotubes with anticancer agent: preparation and antitumor activity.
Topics: Animals; Antineoplastic Agents; Biological Transport; Camptothecin; Cattle; Cell Line, Tumor; Drug Carriers; Esters; Ethylene Glycol; Humans; Hydrophobic and Hydrophilic Interactions; Liver Neoplasms; Mice; Nanotubes, Carbon; Solubility; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Topoisomerase I Inhibitors; Water | 2009 |
Experimental evaluation of inhibitory effect of 10-hydroxycamptothecin on hypoxia-inducible factor-1α expression and angiogenesis in liver tumors after transcatheter arterial embolization.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Catheterization; Embolization, Therapeutic; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Neovascularization, Pathologic; Rabbits; Treatment Outcome; Vascular Endothelial Growth Factor A | 2010 |
A practical strategy for constructing nanodrugs using carbon nanotubes as carriers.
Topics: Amides; Amines; Animals; Camptothecin; Cell Line, Tumor; Drug Carriers; Ethylene Glycol; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Liver Neoplasms; Mice; Nanotubes, Carbon; Oxidation-Reduction; Rats; Succinic Acid; Technetium Tc 99m Pentetate; Tomography, Emission-Computed, Single-Photon | 2011 |
Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine.
Topics: Animals; Antineoplastic Agents; Biological Transport; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemical Phenomena; Delayed-Action Preparations; Drug Carriers; Half-Life; Humans; Ligands; Lipids; Liver Neoplasms; Male; Nanostructures; Neoplasm Proteins; Octreotide; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin | 2011 |
Promoted antitumor activities of acid-labile electrospun fibers loaded with hydroxycamptothecin via intratumoral implantation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzaldehydes; Camptothecin; Carcinoma, Hepatocellular; Electrochemistry; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Lactates; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Molecular Weight; Polyethylene Glycols; Survival Rate; Tumor Microenvironment | 2012 |
[Anti-tumor effects of 10-hydroxycamptothecinc-treated DC-Hepa1-6 fusion vaccines].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cancer Vaccines; Cell Fusion; Cytotoxicity, Immunologic; Dendritic Cells; Female; Liver Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Rats; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 2004 |
[Short-term effects of chemotherapy with combination of hydroxycamptothecine and oxaliplatin in the treatment of advanced digestive tract cancers].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Female; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Stomach Neoplasms; Treatment Outcome | 2004 |
Synthesis and antitumor activity of A-ring modified hexacyclic analogues of camptothecin.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Irinotecan; Liver Neoplasms; Mice; Neoplasm Transplantation; Polycyclic Compounds | 2005 |
Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Flow Cytometry; Fluorouracil; Genes, bcl-2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2006 |
[Effect of hydroxycamptothecin on apoptosis-inducing factor (AIF) expression and on AIF translocation in human hepatocellular cancer cell SMMC-7721].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Translocation, Genetic | 2006 |
[Short-term effects of chemotherapy combined with hydroxycamptothecine and oxaliplatin in treatment of recurrent and metastatic colorectal cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Survival Rate | 2006 |
[Chinese material medica combined with cisplatin and lipiodol through transcatheter arterial embolization in the treatment of primary hepatoma].
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Cantharidin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Female; Hepatic Artery; Humans; Immunotherapy, Adoptive; Iodized Oil; Liver Neoplasms; Male; Middle Aged | 1993 |
Differential regulation of P53, c-Myc, Bcl-2, Bax and AFP protein expression, and caspase activity during 10-hydroxycamptothecin-induced apoptosis in Hep G2 cells.
Topics: alpha-Fetoproteins; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Caspase 3; Caspases; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Differentiation-inducing action of 10-hydroxycamptothecin on human hepatoma Hep G2 cells.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cell Differentiation; Humans; Liver Neoplasms; Proliferating Cell Nuclear Antigen; Telomerase; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Relationship between lactone ring forms of HCPT and their antitumor activities.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Female; Humans; Lactones; Liver Neoplasms; Mice; Sarcoma 180; Tumor Cells, Cultured | 2001 |