10-hydroxycamptothecin has been researched along with Cancer of Colon in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boehm, JC; Caranfa, MJ; Faucette, LF; Gallagher, G; Hecht, SM; Holden, KG; Jakas, DR; Johnson, RK; Kingsbury, WD; McCabe, FL | 1 |
| Chi, AL; Fei, B; Weng, Y | 1 |
| Chen, ZH; Feng, B | 1 |
| Jiang, W; Larrick, JW; Li, L; Wang, Y | 1 |
| Chi, CW; Ho, LK; Lee, HC; Lee, JY; Lu, MF; Ping, YH; Wang, JJ; Wu, PH | 1 |
| Li, S; Wang, A | 1 |
6 other study(ies) available for 10-hydroxycamptothecin and Cancer of Colon
| Article | Year |
|---|---|
Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cattle; Cell Line; Colonic Neoplasms; DNA, Superhelical; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia L1210; Lung Neoplasms; Melanoma, Experimental; Mice; Molecular Structure; Plasmids; Structure-Activity Relationship; Thymus Gland; Topoisomerase I Inhibitors; Transplantation, Heterologous | 1991 |
Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Proliferation; Colonic Neoplasms; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Survivin; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein | 2013 |
[Effect of the change of caspase-3 activity on the neoadjuvant chemotherapy-induced apoptosis of large-intestinal carcinoma cells].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Caspase 3; Caspases; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged | 2003 |
Synthesis and evaluation of a DHA and 10-hydroxycamptothecin conjugate.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Docosahexaenoic Acids; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia L1210; Mice; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship | 2005 |
Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2006 |
Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Diffusion; Drug Carriers; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Rabbits; Treatment Outcome | 2008 |