10-formyltetrahydrofolate and Breast-Neoplasms

10-formyltetrahydrofolate has been researched along with Breast-Neoplasms* in 2 studies

Trials

1 trial(s) available for 10-formyltetrahydrofolate and Breast-Neoplasms

ArticleYear
5-Fluorouracil and 5-formyltetrahydrofolate in advanced malignancies.
    Advances in experimental medicine and biology, 1988, Volume: 244

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Neoplasm Metastasis; Neoplasms; Prostatic Neoplasms

1988

Other Studies

1 other study(ies) available for 10-formyltetrahydrofolate and Breast-Neoplasms

ArticleYear
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
    Cell reports, 2023, 06-27, Volume: 42, Issue:6

    Mitochondrial 10-formyltetrahydrofolate (10-formyl-THF) is utilized by three mitochondrial enzymes to produce formate for nucleotide synthesis, NADPH for antioxidant defense, and formyl-methionine (fMet) to initiate mitochondrial mRNA translation. One of these enzymes-aldehyde dehydrogenase 1 family member 2 (ALDH1L2)-produces NADPH by catabolizing 10-formyl-THF into CO

    Topics: Breast Neoplasms; Female; Formates; Humans; Methionine; NADP; Oxidoreductases Acting on CH-NH Group Donors; Reactive Oxygen Species

2023