10-deazaaminopterin has been researched along with Leukemia in 2 studies
*Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM | 1 |
| Arlin, Z; Currie, VE; Greene, G; Sirotnak, FM; Tan, C; Warrell, RP; Young, CW | 1 |
2 other study(ies) available for 10-deazaaminopterin and Leukemia
| Article | Year |
|---|---|
Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins.
Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Methotrexate; Molecular Structure; Tumor Cells, Cultured | 1990 |
Phase I trial of 10-deaza-aminopterin in patients with advanced cancer.
Topics: Adult; Aminopterin; Bone Marrow; Drug Administration Schedule; Drug Evaluation; Folic Acid Antagonists; Humans; Infusions, Parenteral; Injections, Intravenous; Leukemia; Mucous Membrane; Skin | 1983 |