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10-deazaaminopterin and Leukemia L 1210

10-deazaaminopterin has been researched along with Leukemia L 1210 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM1
Bridges, TW; Gaumont, Y; Henkel, TJ; Kisliuk, RL; Nair, MG; Sirotnak, FM1
Brown, VH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM; Tagawa, H1
Colwell, WT; DeGraw, JI; Piper, JR; Sirotnak, FM1
Chello, PL; DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM1
Chiao, JH; Roy, K; Sirotnak, FM; Tolner, B1
DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM1
Fanucchi, MP; Farag, F; Kinahan, JJ; Samuels, LL; Sirotnak, FM; Vidal, PM; Young, CW1
Moccio, DM; Samuels, LL; Sirotnak, FM1

Other Studies

9 other study(ies) available for 10-deazaaminopterin and Leukemia L 1210

ArticleYear
Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Methotrexate; Molecular Structure; Tumor Cells, Cultured

1990
Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:9

    Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chemical Phenomena; Chemistry; Lacticaseibacillus casei; Leukemia L1210; Mice; Streptococcus

1981
Synthesis and antitumor activity of 10-alkyl-10-deazaminopterins. A convenient synthesis of 10-deazaminopterin.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:10

    Topics: Aminopterin; Animals; Antineoplastic Agents; Bacteria; Chemical Phenomena; Chemistry; Kinetics; Leukemia L1210; Mice

1982
Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin.
    Journal of medicinal chemistry, 1993, Jul-23, Volume: 36, Issue:15

    Topics: Aminopterin; Animals; Antineoplastic Agents; Female; Leukemia L1210; Mammary Neoplasms, Experimental; Mice; Structure-Activity Relationship

1993
Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Membranes; Methotrexate; Mice; Sarcoma 180; Tetrahydrofolate Dehydrogenase

1982
A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter within
    The Journal of biological chemistry, 1998, Jan-30, Volume: 273, Issue:5

    Topics: Amino Acid Sequence; Aminopterin; Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Membrane; Drug Resistance, Neoplasm; Folic Acid Antagonists; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Protein Conformation; Sarcoma 180; Sequence Homology, Amino Acid; Tumor Cells, Cultured

1998
Antitumor properties of a new folate analog, 10-deaza-aminopterin, in mice.
    Cancer treatment reports, 1978, Volume: 62, Issue:7

    Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinical; Female; Folic Acid; Leukemia L1210; Liver Neoplasms; Male; Methotrexate; Mice; Neoplasms, Experimental; Plasmacytoma; Sarcoma 180

1978
Fluorometric high-performance liquid chromatographic analysis of 10-deazaaminopterin, 10-ethyl-10-deazaaminopterin, and known metabolites.
    Analytical biochemistry, 1985, Volume: 150, Issue:1

    Topics: Aminopterin; Animals; Chromatography, High Pressure Liquid; Humans; Leukemia L1210; Mice; Mice, Nude; Neoplasms; Polyglutamic Acid; Spectrometry, Fluorescence

1985
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay

1985