Page last updated: 2024-10-20

1-propanol and Insulin Resistance

1-propanol has been researched along with Insulin Resistance in 4 studies

1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the potential beneficial effects of Armolipid Plus (AP) (berberine 500 mg, red yest rice, monacolin K 3 mg and policosanol 10 mg) on insulin resistance, lipid profile, particularly on small and dense LDL cholesterol (sdLDL-C), representing the most atherogenic components, as well as its effects on high sensitivity C-reactive protein, a notable marker of cardiovascular risk, blood pressure and cardiac remodeling in subjects affected by MetS, with left ventricular hypertrophy."5.30Efficacy of a nutraceutical combination on lipid metabolism in patients with metabolic syndrome: a multicenter, double blind, randomized, placebo controlled trial. ( Battista, F; Bonaduce, D; Bosso, G; Brambilla, N; D'Amato, M; Fazio, V; Galletti, F; Gentile, M; Giacovelli, G; Mercurio, V; Pucci, G; Schillaci, G; Vitalini, C, 2019)
" We evaluated the effects of a nutraceutical combination (NC), consisting of 500 mg berberine, 200mg red yeast rice and 10mg policosanols, on cholesterol levels and endothelial function in patients with hypercholesterolemia."5.14Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. ( Affuso, F; Fazio, S; Micillo, F; Ruvolo, A; Saccà, L, 2010)
" However, policosanol, a mixture of long-chain aliphatic alcohols extractable from sugar cane wax, has shown cholesterol-lowering potency comparable to that of statins, and yet appears to be devoid of toxic risk."1.31Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen. ( McCarty, MF, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galletti, F1
Fazio, V1
Gentile, M1
Schillaci, G1
Pucci, G1
Battista, F1
Mercurio, V2
Bosso, G1
Bonaduce, D1
Brambilla, N1
Vitalini, C1
D'Amato, M1
Giacovelli, G1
Affuso, F1
Ruvolo, A2
Micillo, F1
Saccà, L1
Fazio, S2
Carlomagno, G1
Pirozzi, C1
McCarty, MF1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Policosanol on Elderly Patients With Endothelial Dysfunction[NCT02543099]Phase 3100 participants (Anticipated)Interventional2015-06-30Recruiting
Effect of a Nutraceutical Combination on Endothelial Injury and C-reactive Protein in Patients With Low-grade Systemic Inflammation[NCT02422927]Phase 4100 participants (Actual)Interventional2014-07-31Completed
The Study of Berberine Affecting Metabolism, Inflammation Status, Endothelial Function and Thrombotic Events in Patients With Coronary Artery Disease by Remodeling Gut Microbiota[NCT04434365]Phase 1/Phase 224 participants (Actual)Interventional2019-06-21Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for 1-propanol and Insulin Resistance

ArticleYear
Efficacy of a nutraceutical combination on lipid metabolism in patients with metabolic syndrome: a multicenter, double blind, randomized, placebo controlled trial.
    Lipids in health and disease, 2019, Mar-18, Volume: 18, Issue:1

    Topics: Adult; Aged; Berberine; Cholesterol, LDL; Dietary Supplements; Double-Blind Method; Fatty Alcohols;

2019
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:9

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Sup

2010
Effects of a nutraceutical combination on left ventricular remodeling and vasoreactivity in subjects with the metabolic syndrome.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2012, Volume: 22, Issue:5

    Topics: Anticholesteremic Agents; Berberine; Cardiotonic Agents; Dietary Supplements; Fatty Alcohols; Female

2012

Other Studies

1 other study available for 1-propanol and Insulin Resistance

ArticleYear
Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen.
    Medical hypotheses, 2002, Volume: 59, Issue:3

    Topics: Animals; Cholesterol, LDL; Clinical Trials as Topic; Cohort Studies; Diet, Vegetarian; Dietary Fats;

2002