Page last updated: 2024-10-20

1-propanol and Body Weight

1-propanol has been researched along with Body Weight in 35 studies

1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" No signs of toxic effects related to the test material were observed in the dams F0 during pregnancy and lactation."1.30Evaluation of peri- and post-natal toxicity of Policosanol in rats. ( Garcia, H; Rodríguez, MD, 1998)
" Overall, policosanol was well tolerated throughout the study and no toxic symptoms were observed."1.29Toxicity of policosanol in beagle dogs: one-year study. ( Alemán, CL; Capote, A; Gámez, R; García, M; Hernández, C; Más, R; Mesa, AR; Noa, M; Rodeiro, I, 1994)
" The greater potency of PMC and T4P compared to CPA is likely the result of these compounds bypassing important detoxification steps, therefore, more of the parent compound reaches the ovary as the toxic metabolite."1.28Phosphoramide mustard is responsible for the ovarian toxicity of cyclophosphamide. ( Mattison, DR; Plowchalk, DR, 1991)
"Epichlorohydrin also did not produce a statistically significant increase in the average percent of malformed mouse fetuses, even at 160 mg/kg."1.26Teratogenic evaluation of epichlorohydrin in the mouse and rat and glycidol in the mouse. ( Gerling, FS; Marks, TA; Staples, RE, 1982)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199011 (31.43)18.7374
1990's13 (37.14)18.2507
2000's9 (25.71)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, KH1
Yadav, D1
Kim, SJ1
Kim, JR1
Sharma, R1
Matsuzaka, T1
Kaushik, MK1
Sugasawa, T1
Ohno, H1
Wang, Y2
Motomura, K1
Shimura, T1
Okajima, Y1
Mizunoe, Y1
Ma, Y1
Saber, ZM1
Iwasaki, H2
Yatoh, S1
Suzuki, H1
Aita, Y1
Han, SI1
Takeuchi, Y1
Yahagi, N1
Miyamoto, T1
Sekiya, M1
Nakagawa, Y1
Shimano, H1
Francini-Pesenti, F1
Brocadello, F1
Beltramolli, D1
Nardi, M1
Caregaro, L1
Okabe, T1
Toda, T1
Inafuku, M1
Wada, K1
Oku, H1
Kassis, AN2
Kubow, S1
Jones, PJ4
Wang, YW1
Pischel, I1
Fairow, C2
Ebine, N2
Jia, X1
Jaeger, R1
Gámez, R2
Máz, R1
Arruzazabala, ML1
Mendoza, S1
Castaño, G1
Setnikar, I1
Senin, P1
Rovati, LC1
Marinangeli, CP1
Jain, D1
Alemán, CL3
Más Ferreiro, R1
Noa Puig, M1
Rodeiro Guerra, I1
Hernández Ortega, C1
Capote, A3
Mesa, AR1
Más, R2
Noa, M2
Hernández, C2
Rodeiro, I2
García, M1
Cerejido, E1
Menéndez, R1
Amor, A1
Fraga, V1
Rodríguez, MD1
Garcia, H1
Marks, TA1
Gerling, FS1
Staples, RE1
Martel, ML1
Baumgardner, CA1
Dybas, LK1
Geer, BW1
Burleigh-Flayer, HD1
Gill, MW1
Strother, DE1
Masten, LW1
McKee, RH1
Tyler, TR1
Gardiner, T2
Teramoto, K1
Wakitani, F1
Horiguchi, S1
Jo, T1
Yamamoto, T1
Mitsutake, H1
Nakaseko, H1
Takayasu, T1
Ohshima, T1
Tanaka, N1
Maeda, H1
Kondo, T1
Nishigami, J1
Nagano, T1
Burleigh-Flayer, H1
Garman, R1
Neptun, D1
Bevan, C1
Kapp, R1
Tyler, T1
Wright, G1
Sanchis-Segura, C1
Correa, M1
Aragon, CM1
Carpanini, FM1
Gaunt, IF1
Hardy, J1
Gangolli, SD1
Butterworth, KR1
Lloyd, AG1
Berman, E1
House, DE1
Allis, JW1
Simmons, JE1
Adachi, K1
Wakabayashi, T1
Popinigis, J1
Plowchalk, DR1
Mattison, DR1
Jenkinson, PC1
Anderson, D1
Klinger, W1
Devereux, T1
Maronpot, R1
Fouts, J1
Kniepert, E1
Görisch, V1
Okada, M1
Hashimoto, Y1
Hofrichter, G1
Hampel, H1
Liehn, HD1
Ludwig, E1
Carlson, DA1
Banks, WA1
Wojcik, DP1
McCollister, SB1
Kociba, RJ1
McCollister, DD1
Makdani, D1
Bergen, WG1
Mickelsen, O1
Huber, JT1
Sanz, F1
Jurado, R1
Tarazona, JM1
Frías, J1
Illera, M1
Pérez, M1
Stillings, BR1
Hammerle, OA1
Snyder, DG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inhalation Intervention for Nausea in the Emergency Department[NCT02092441]80 participants (Actual)Interventional2014-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Nausea Verbal Numerical Rating Scale (0-10) at 10 Minutes Post Intervention

"Primary outcome is nausea and vomiting measured on a scale from 0 (no nausea) to 10 (worst nausea imaginable) Verbal Numerical Response Scale (VNRS) at 10 minutes post intervention." (NCT02092441)
Timeframe: 10 minutes post intervention

InterventionVNRS (Median)
Alcohol Prep Pad Group3
Normal Saline Prep Pad6

Satisfaction Measured on a 5-point Likert Scale

"Patient satisfaction of smelling prep pad to alleviate nausea on a scale from 1 (completely unsatisfied) to 5 (completely satisfied)" (NCT02092441)
Timeframe: 10 minutes post intervention

Intervention5 point Likert Scale (Median)
Alcohol Prep Pad Group4
Normal Saline Prep Pad2

Verbal Numerical Rating Scale Pain Score (0-10) at 10 Minutes Post Intervention

"Scale ranges from 0 (no pain) to 10 (worst pain imaginable)" (NCT02092441)
Timeframe: 10 minutes post intervention

InterventionVNRS (Median)
Alcohol Prep Pad Group6
Normal Saline Prep Pad6

Trials

2 trials available for 1-propanol and Body Weight

ArticleYear
Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled study.
    Complementary therapies in medicine, 2008, Volume: 16, Issue:2

    Topics: Anticholesteremic Agents; Body Mass Index; Body Weight; Cholesterol; Complementary Therapies; Diet;

2008
Sugar cane policosanols do not reduce LDL oxidation in hypercholesterolemic individuals.
    Lipids, 2009, Volume: 44, Issue:5

    Topics: Anticholesteremic Agents; Body Weight; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; En

2009

Other Studies

33 other studies available for 1-propanol and Body Weight

ArticleYear
Blood Pressure Lowering Effect of Cuban Policosanol is Accompanied by Improvement of Hepatic Inflammation, Lipoprotein Profile, and HDL Quality in Spontaneously Hypertensive Rats.
    Molecules (Basel, Switzerland), 2018, May-03, Volume: 23, Issue:5

    Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Antioxidants; Blood Pressure; Body Weigh

2018
Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism.
    Scientific reports, 2019, 03-26, Volume: 9, Issue:1

    Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Diet, High-Fat; Fatt

2019
Antiatherosclerotic function of Kokuto, Okinawan noncentrifugal cane sugar.
    Journal of agricultural and food chemistry, 2009, Jan-14, Volume: 57, Issue:1

    Topics: Animals; Antioxidants; Atherosclerosis; Body Weight; Cholesterol, Dietary; Coturnix; Diet, Atherogen

2009
Effects of policosanols and phytosterols on lipid levels and cholesterol biosynthesis in hamsters.
    Lipids, 2003, Volume: 38, Issue:2

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Cricetinae; Diet; Drug Synergism; Fatty

2003
Very long chain fatty acids (policosanols) and phytosterols affect plasma lipid levels and cholesterol biosynthesis in hamsters.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:4

    Topics: Animals; Body Weight; Cholesterol; Cholesterol, HDL; Cricetinae; Eating; Fatty Alcohols; Kinetics; L

2005
Effects of concurrent therapy with policosanol and omega-3 fatty acids on lipid profile and platelet aggregation in rabbits.
    Drugs in R&D, 2005, Volume: 6, Issue:1

    Topics: Animals; Body Weight; Cholesterol; Drug Synergism; Eating; Eicosapentaenoic Acid; Fatty Acids, Omega

2005
Antiatherosclerotic efficacy of policosanol, red yeast rice extract and astaxanthin in the rabbit.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:6

    Topics: Animals; Anticholesteremic Agents; Aorta; Arteriosclerosis; beta Carotene; Body Weight; Cholesterol;

2005
Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters.
    Atherosclerosis, 2007, Volume: 194, Issue:1

    Topics: Animal Feed; Animals; Anticholesteremic Agents; Body Weight; Cholesterol, Dietary; Cholesterol, HDL;

2007
Carcinogenicity of policosanol in Sprague Dawley rats: a 24 month study.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:5

    Topics: Animals; Anticholesteremic Agents; Body Weight; Carcinogenicity Tests; Fatty Alcohols; Female; Male;

1994
Toxicity of policosanol in beagle dogs: one-year study.
    Toxicology letters, 1994, Volume: 73, Issue:2

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Blood Chemical Analysis; Body Weight; Dogs;

1994
A 12-month study of policosanol oral toxicity in Sprague Dawley rats.
    Toxicology letters, 1994, Volume: 70, Issue:1

    Topics: Administration, Oral; Analysis of Variance; Animals; Biomarkers; Blood Chemical Analysis; Body Weigh

1994
Evaluation of peri- and post-natal toxicity of Policosanol in rats.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:1

    Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Behavior, Animal; Body Weight; Fatty Alcohols;

1998
Teratogenic evaluation of epichlorohydrin in the mouse and rat and glycidol in the mouse.
    Journal of toxicology and environmental health, 1982, Volume: 9, Issue:1

    Topics: 1-Propanol; Animals; Body Weight; Chlorohydrins; Dose-Response Relationship, Drug; Epichlorohydrin;

1982
The toxicities of short-chain primary alcohols and the accumulation of storage bodies in the larval fat body of Drosophila melanogaster.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 111, Issue:1

    Topics: 1-Butanol; 1-Propanol; Alcohol Dehydrogenase; Alcohols; Analysis of Variance; Animals; Body Weight;

1995
Isopropanol 13-week vapor inhalation study in rats and mice with neurotoxicity evaluation in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 23, Issue:3

    Topics: 1-Propanol; Administration, Inhalation; Animals; Blood; Body Weight; Brain; Eating; Female; Kidney;

1994
Comparison of the neurotoxicity of several chemicals estimated by the peripheral nerve conduction velocity in rats.
    Environmental research, 1993, Volume: 62, Issue:1

    Topics: 1-Propanol; Animals; Body Weight; Lead; Male; Manganese Poisoning; Neural Conduction; Peripheral Ner

1993
Postmortem degradation of administered ethanol-d6 and production of endogenous ethanol: experimental studies using rats and rabbits.
    Forensic science international, 1995, Dec-18, Volume: 76, Issue:2

    Topics: 1-Propanol; Animals; Autopsy; Body Weight; Deuterium; Ethanol; Gas Chromatography-Mass Spectrometry;

1995
Isopropanol vapor inhalation oncogenicity study in Fischer 344 rats and CD-1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 36, Issue:2

    Topics: 1-Propanol; Administration, Inhalation; Animals; Atmosphere Exposure Chambers; Body Weight; Carcinog

1997
Lession on the hypothalamic arcuate nucleus by estradiol valerate results in a blockade of ethanol-induced locomotion.
    Behavioural brain research, 2000, Volume: 114, Issue:1-2

    Topics: 1-Propanol; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Caffeine; Central Nervous System

2000
Short-term toxicity of allyl alcohol in rats.
    Toxicology, 1978, Volume: 9, Issue:1-2

    Topics: 1-Propanol; Allyl Compounds; Animals; Body Weight; Diet; Drinking; Eating; Female; Flavoring Agents;

1978
Hepatotoxic interactions of ethanol with allyl alcohol or carbon tetrachloride in rats.
    Journal of toxicology and environmental health, 1992, Volume: 37, Issue:1

    Topics: 1-Propanol; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body W

1992
Effects of alkyl alcohols and related chemicals on rat liver structure and function. II. Some biochemical properties of ethanol-, propanol- and butanol-treated rat liver mitochondria.
    Acta pathologica japonica, 1991, Volume: 41, Issue:6

    Topics: 1-Propanol; Alcohols; Animals; Body Weight; Butanols; Cell Fractionation; Cytochromes; Electron Tran

1991
Phosphoramide mustard is responsible for the ovarian toxicity of cyclophosphamide.
    Toxicology and applied pharmacology, 1991, Mar-01, Volume: 107, Issue:3

    Topics: 1-Propanol; Acrolein; Animals; Body Weight; Cyclophosphamide; Dose-Response Relationship, Drug; Fema

1991
Malformed foetuses and karyotype abnormalities in the offspring of cyclophosphamide and allyl alcohol-treated male rats.
    Mutation research, 1990, Volume: 229, Issue:2

    Topics: 1-Propanol; Abnormalities, Drug-Induced; Animals; Blood Cells; Body Weight; Chromosome Aberrations;

1990
Functional hepatocellular heterogeneity determined by the hepatotoxins allyl alcohol and bromobenzene in immature and adult Fischer 344 rats.
    Toxicology and applied pharmacology, 1986, Mar-30, Volume: 83, Issue:1

    Topics: 1-Propanol; Aging; Animals; Body Weight; Bromobenzenes; Cytochrome P-450 Enzyme System; Glucose-6-Ph

1986
Influence of alcohol pretreatment on effects of chloroform in rats.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:2

    Topics: 1-Propanol; Alanine Transaminase; Animals; Body Weight; Chloroform; Drinking Behavior; Drug Synergis

1988
Carcinogenic effect of N-nitrosoamines related to butyl(4-hydroxybutyl)nitrosoamine in ACI-N rats, with special reference to induction of urinary bladder tumors.
    Gan, 1974, Volume: 65, Issue:1

    Topics: 1-Propanol; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body W

1974
[Pharmacologic evaluation of 3-butoxy-l-phenoxy-propanol-(2), a new substance with choleretic activity].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:1

    Topics: 1-Propanol; Animals; Anticonvulsants; Bile; Bile Acids and Salts; Body Weight; Cats; Cholagogues and

1974
Distortion of mirex residues in insects owing to use of isopropyl alcohol as a collection solvent.
    Bulletin of environmental contamination and toxicology, 1973, Volume: 9, Issue:6

    Topics: 1-Propanol; Animals; Ants; Body Weight; Chemical Phenomena; Chemistry; Cockroaches; Insecta; Insecti

1973
Dietary feeding studies of methylcellulose and hydroxypropylmethylcellulose in rats and dogs.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:6

    Topics: 1-Propanol; Alanine Transaminase; Alkaline Phosphatase; Animals; Blood Urea Nitrogen; Body Weight; D

1973
Factors influencing the nutritive value of 1,2-dichloroethane-extracted fish protein concentrate in rat diets.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:12

    Topics: 1-Propanol; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Caseins;

1971
[Standards for the study of teratogenic and embryopathic action in dogs].
    Archivos del Instituto de Farmacologia Experimental (Medicina), 1970, Volume: 22, Issue:1-2

    Topics: 1-Propanol; Administration, Oral; Allyl Compounds; Animals; Barbiturates; Body Weight; Diethylamines

1970
Sequence of limiting amino acids in fish protein concentrate produced by isopropyl alcohol extraction of red hake (Urophycis chuss).
    The Journal of nutrition, 1969, Volume: 97, Issue:1

    Topics: 1-Propanol; Amino Acids; Animals; Arginine; Body Weight; Feeding Behavior; Fish Products; Glutamates

1969