1-o-hexadecyl-2-n-methylcarbamylphosphatidylcholine has been researched along with Leukemia, Erythroblastic, Acute in 1 studies
1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine: biologically active analog of PAF; structure given in first source
Leukemia, Erythroblastic, Acute: A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using murine erythroleukemia cells (MELCs) as the model, we found that WEB-2086, a triazolobenzodiazepine-derived PAF antagonist originally developed as an anti-inflammatory drug, induces a dose-dependent inhibition of MELC growth and hemoglobin accumulation as a result of a true commitment to differentiation." | 1.31 | Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells. ( Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cellai, C | 1 |
| Laurenzana, A | 1 |
| Vannucchi, AM | 1 |
| Della Malva, N | 1 |
| Bianchi, L | 1 |
| Paoletti, F | 1 |
1 other study available for 1-o-hexadecyl-2-n-methylcarbamylphosphatidylcholine and Leukemia, Erythroblastic, Acute
| Article | Year |
|---|---|
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relatio | 2002 |