Page last updated: 2024-08-21

1-naphthylisothiocyanate and Necrosis

1-naphthylisothiocyanate has been researched along with Necrosis in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Fujimoto, T; Funakoshi, T; Ikeda, T; Kawaguchi, S; Nakai, K; Okamura, T; Otake, S; Saito, Y; Takahashi, K; Tomonari, Y; Uchida, H; Yamamoto, D1
Cline-Fedewa, H; Copple, BL; Flick, MJ; Joshi, N; Kopec, AK; Luyendyk, JP; O'Brien, KM; Towery, KL; Williams, KJ1
Cline-Fedewa, H; Flick, MJ; Joshi, N; Kopec, AK; Luyendyk, JP; Nault, R; Nawabi, A; Ray, JL; Rockwell, CE; Schmitt, T; Zacharewski, TR1
Joshi, N; Kopec, AK; Luyendyk, JP; Ray, JL1
He, X; Li, H; Li, K; Li, P; Li, R; Liu, H; Ma, X; Wang, J; Wei, S; Wen, J; Xiao, X; Zhao, Y; Zhou, X; Zhu, Y1
Luyendyk, JP; Sullivan, BP; Tawfik, O; Wang, R1
Luyendyk, JP; Mackman, N; Sullivan, BP1
Leonard, TB; Neptun, DA; Popp, JA1
Goldstein, RS; Handler, JA; Kossor, DC; Meunier, PC; Sozio, RS1
Chamow, SM; Godowski, PJ; Roos, F; Schwall, RH; Terrell, TG1
Bulle, F; Dhumeaux, D; Guellaën, G; Lescs, MC; Mavier, P; Preaux, AM; Siegrist, S; Zafrani, ES1
Carakostas, MC; Church, GE; Cleghorn, BL; Gossett, KA1

Other Studies

12 other study(ies) available for 1-naphthylisothiocyanate and Necrosis

ArticleYear
Effects of microsampling on toxicity evaluation of 1-naphthylisothiocyanate (ANIT), a hepatotoxic substance, in a mouse toxicity study.
    The Journal of toxicological sciences, 2023, Volume: 48, Issue:11

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Liver; Mice; Necrosis

2023
Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice.
    Journal of thrombosis and haemostasis : JTH, 2015, Volume: 13, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Antithrombin III; Bile Acids and Salts; Blood Coagulation; Blood Platelets; Chemical and Drug Induced Liver Injury; Cholestasis; Fibrinogens, Abnormal; Genotype; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred C57BL; Mice, Knockout; Mutation; Necrosis; Peptide Hydrolases; Phenotype; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Serotonin; Signal Transduction

2015
Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism.
    Blood, 2016, 06-02, Volume: 127, Issue:22

    Topics: 1-Naphthylisothiocyanate; Animals; Benzoates; Bile Ducts; Cell Adhesion; Female; Fibrin; Humans; Hyperplasia; Inflammation; Interferon-gamma; Liver Cirrhosis, Biliary; Macrophage-1 Antigen; Male; Mice; Mice, Knockout; Necrosis; Thiohydantoins

2016
Dose-dependent effects of alpha-naphthylisothiocyanate disconnect biliary fibrosis from hepatocellular necrosis.
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Liver; Liver Cirrhosis, Biliary; Male; Mice; Necrosis

2017
Paeoniflorin ameliorates cholestasis via regulating hepatic transporters and suppressing inflammation in ANIT-fed rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: 1-Naphthylisothiocyanate; Animals; Bile; Biomarkers; Carrier Proteins; Cholestasis; Edema; Glucosides; Inflammation; Liver; Liver Function Tests; Male; Monoterpenes; Necrosis; Neutrophil Infiltration; NF-kappa B; Rats; Rats, Sprague-Dawley

2017
Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Antibodies, Monoclonal; Biomarkers; Blood Coagulation; Blood Platelets; Cholestasis, Intrahepatic; Clopidogrel; Gene Expression; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Necrosis; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Thromboplastin; Ticlopidine

2010
Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 119, Issue:1

    Topics: 1-Naphthylisothiocyanate; Acute Disease; Animals; Blood Coagulation; Chemical and Drug Induced Liver Injury; Cholestasis; Disease Models, Animal; Female; Fibrinogen; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Receptor, PAR-1; Receptors, Proteinase-Activated; Xenobiotics

2011
Serum gamma glutamyl transferase as a specific indicator of bile duct lesions in the rat liver.
    The American journal of pathology, 1984, Volume: 116, Issue:2

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Bile Duct Diseases; Bile Ducts, Intrahepatic; Carbon Tetrachloride; gamma-Glutamyltransferase; Hyperplasia; Male; Necrosis; Propanols; Rats; Rats, Inbred F344

1984
Temporal relationship of changes in hepatobiliary function and morphology in rats following alpha-naphthylisothiocyanate (ANIT) administration.
    Toxicology and applied pharmacology, 1993, Volume: 119, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Bile; Bile Acids and Salts; Biliary Tract; Cholestasis; Dose-Response Relationship, Drug; Erythritol; Liver; Male; Necrosis; Perfusion; Rats; Rats, Sprague-Dawley

1993
Reduction of alpha-naphthylisothiocyanate-induced hepatotoxicity by recombinant human hepatocyte growth factor.
    Endocrinology, 1992, Volume: 131, Issue:6

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis, Intrahepatic; Hepatocyte Growth Factor; Liver; Male; Necrosis; Rats; Recombinant Proteins

1992
Mechanism of gamma-glutamyl transpeptidase release in serum during intrahepatic and extrahepatic cholestasis in the rat: a histochemical, biochemical and molecular approach.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: 1-Naphthylisothiocyanate; Animals; Bile; Bile Ducts, Intrahepatic; Bilirubin; Blotting, Northern; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Common Bile Duct; gamma-Glutamyltransferase; Histocytochemistry; Ligation; Liver; Male; Necrosis; Rats; Rats, Inbred Strains; RNA, Messenger

1990
Evaluating toxin-induced hepatic injury in rats by laboratory results and discriminant analysis.
    Veterinary pathology, 1986, Volume: 23, Issue:3

    Topics: 1-Naphthylisothiocyanate; 1-Propanol; 5'-Nucleotidase; Alanine Transaminase; Animals; Carbon Tetrachloride; Enzymes; Glutamate Dehydrogenase; Isocitrate Dehydrogenase; L-Iditol 2-Dehydrogenase; Liver; Male; Models, Biological; Necrosis; Nucleotidases; Propanols; Rats; Rats, Inbred Strains; Thiocyanates

1986