Page last updated: 2024-08-21

1-naphthylisothiocyanate and Liver Diseases

1-naphthylisothiocyanate has been researched along with Liver Diseases in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's10 (29.41)18.2507
2000's10 (29.41)29.6817
2010's4 (11.76)24.3611
2020's5 (14.71)2.80

Authors

AuthorsStudies
Jiang, T; Li, J; Liu, J; Liu, S; Luo, S; Lv, Z; Qian, B; Shi, J; Yang, Z; Zhao, Z; Zhou, L; Zhou, Y1
Cai, J; Li, Y; Ma, Y; Peng, X; Shi, R; Tian, T; Wang, T; Wu, J; Zhang, L; Zou, J1
Ahmed A Saad, A; Baldi, S; Refat, M; Wu, X; Zhang, G; Zheng, F1
Hu, Q; Ji, H; Li, L; Li, T; Wang, X; Xu, L; Zheng, R1
Feng, SL; Jin, H; Yuan, Z; Zhang, J; Zhu, WT1
Bothe, MK; Harleman, J; Meyer, C; Mueller, U; Queudot, JC; Roger, V; Westphal, M1
Bi, KS; Chen, KL; Han, F; Mao, XJ; Yin, R; Zhang, XS; Zhu, HY1
Groen, AK; Hoekstra, M; Ouweneel, AB; van der Geest, R; van der Sluis, RJ; Van Eck, M1
Cao, HX; Jiang, XG; Liu, L; Lu, HT; Sun, H; Sun, WJ; Wang, P; Wang, XJ; Wu, ZM; Zhang, GM; Zhou, J1
Haber, MM; Katz, MS; Schwartz, MZ; Thatch, KA1
Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP; Santos, MS; Seiça, R1
Beckwith-Hall, BM; Holmes, E; Lindon, JC; Nicholson, JK; Thompson, NA1
Li, X; Li, Z; Pei, F; Wu, H; Wu, Y; Zhang, X1
Adler, R; Amacher, DE; Herath, A; Townsend, RR1
Choi, J; Jung, HJ; Kim, WB; Lee, JH; Lee, KT; Park, HJ; Park, JK; Park, KK1
Azmi, J; Griffin, JL; Holmes, E; Nicholson, JK; Shore, RF1
Alpini, G; Demorrow, S; Fava, G; Francis, H; Glaser, S; Lesage, G; Marzioni, M; Venter, J1
Adjarov, D; Ivanov, E; Naidenova, E; Petrova, S1
Ikeda, Y; Imai, E; Ito, K; Nose, T; Sato, I; Tajima, S; Takebe, H1
Fregnan, GB; Frigerio, L; Porta, R; Prada, M; Ruggieri, F1
Inoue, T; Kamogawa, A; Ohta, S; Sakurai, N; Sato, N; Shinoda, M1
Bailie, MB; Carter, GW; Dahm, LJ; Harris, RR; Peters-Golden, M; Roth, RA1
Ohta, S; Sato, N; Shinoda, M; Tu, SH1
Clark, RL; Lichtman, SN; Wang, J1
Lai, TY; Lin, JG; Lin, WC; Wu, YW1
Aoki, Y; Itoh, H; Numakami, K; Ogawa, Z1
Chang, YS; Ho, LK; Lin, CC; Lu, KL; Tsai, CC1
Antti, H; Azmi, J; Griffin, JL; Holmes, E; Johansson, E; Nicholson, JK; Shore, RF1
Gallenkamp, H1
Fujita, T; Iwasaki, T; Kumazawa, N; Nakamura, H; Ohta, S; Shinoda, M1
Klaassen, CD; Liu, J; Madhu, C; Maziasz, TJ1
Etoh, H; Ishikawa, A; Misawa, S; Nakano, M; Tanaka, E1
Bay, MK; Johnson, RF; Leighton, JA; Maldonado, AL; Schenker, S; Speeg, KV1
Ito, K; Nishimura, N; Tajima, S1

Reviews

1 review(s) available for 1-naphthylisothiocyanate and Liver Diseases

ArticleYear
Heterogeneity of the intrahepatic biliary epithelium.
    World journal of gastroenterology, 2006, Jun-14, Volume: 12, Issue:22

    Topics: 1-Naphthylisothiocyanate; Animals; Apoptosis; Bile Acids and Salts; Bile Duct Diseases; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Cell Proliferation; Epithelial Cells; Hepatectomy; Humans; Ligation; Liver Diseases

2006

Other Studies

33 other study(ies) available for 1-naphthylisothiocyanate and Liver Diseases

ArticleYear
IL-25 ameliorates acute cholestatic liver injury via promoting hepatic bile acid secretion.
    Cytokine, 2022, Volume: 158

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Cholestasis; Interleukin-17; Liver; Liver Diseases; Mice; Mice, Inbred C57BL

2022
Identification of Yinchenwuling fang's active components and hepatoprotective effects against cholestatic liver damage induced by alpha-naphthyl isothiocyanate in mice.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023, Jan-15, Volume: 1215

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Cholestasis; Isothiocyanates; Liver; Liver Diseases; Mice

2023
7, 8-Dihydroxy-4-methyl coumarin alleviates cholestasis via activation of the Farnesoid X receptor in vitro and in vivo.
    Chemico-biological interactions, 2023, Jan-25, Volume: 370

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Coumarins; Liver; Liver Diseases; Mice; Molecular Docking Simulation; Receptors, Cytoplasmic and Nuclear

2023
Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 68

    Topics: 1-Naphthylisothiocyanate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Cholestasis; Cinnamates; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Iridoid Glucosides; Liver; Liver Diseases; Male; Mice, Inbred C57BL; Protective Agents; Receptors, Cytoplasmic and Nuclear

2020
A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Mar-03, Volume: 27

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholangitis; Cholestasis; Disease Models, Animal; Hepatitis; Hepatocytes; Hypericum; Kaempferols; Liver; Liver Diseases; Luteolin; Male; Oxidative Stress; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley

2021
Characterization of a rat model of moderate liver dysfunction based on alpha-naphthylisothiocyanate-induced cholestasis.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:6

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis; Disease Models, Animal; Humans; Liver Diseases; Rats, Wistar; Serum Albumin; Severity of Illness Index; Time Factors

2017
Evaluation of the protective effect of Zhi-Zi-da-Huang decoction on acute liver injury with cholestasis induced by α-naphthylisothiocyanate in rats.
    Journal of ethnopharmacology, 2015, Aug-22, Volume: 172

    Topics: 1-Naphthylisothiocyanate; Acute Disease; Animals; Antioxidants; Cholestasis; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Liver Diseases; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley

2015
Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice.
    Toxicology and applied pharmacology, 2016, 09-01, Volume: 306

    Topics: 1-Naphthylisothiocyanate; Adrenalectomy; Animals; Bile Acids and Salts; Cholestasis; Cholesterol; Corticosterone; Hypercholesterolemia; Liver; Liver Diseases; Mice, Inbred C57BL; Mifepristone; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid

2016
Comparative study on the protective effects of Yinchenhao Decoction against liver injury induced by alpha-naphthylisothiocyanate and carbon tetrachloride.
    Chinese journal of integrative medicine, 2009, Volume: 15, Issue:3

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Annonaceae; Aspartate Aminotransferases; Bilirubin; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Glutathione; Hepatocytes; Jaundice; Liver; Liver Diseases; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase

2009
Growth factor modulation of hepatic inflammation: a novel approach to the management of total parenteral nutrition-associated liver disease.
    Journal of pediatric surgery, 2010, Volume: 45, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Disease Models, Animal; Female; Hepatocyte Growth Factor; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Liver; Liver Diseases; Liver Failure; Liver Function Tests; Parenteral Nutrition, Total; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome; Tumor Necrosis Factor-alpha

2010
Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2003, Volume: 22, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Calcium; Cardiovascular Diseases; Cholestasis; Chronic Disease; Cyclosporine; Disease Models, Animal; Female; Fibrosis; Liver Diseases; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar

2003
A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum.
    The Analyst, 2003, Volume: 128, Issue:7

    Topics: 1-Naphthylisothiocyanate; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Lipoproteins; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Principal Component Analysis; Rats; Rats, Sprague-Dawley

2003
Comparison of metabolic profiles from serum from hepatotoxin-treated rats by nuclear-magnetic-resonance-spectroscopy-based metabonomic analysis.
    Analytical biochemistry, 2005, May-01, Volume: 340, Issue:1

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hydrazines; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Pattern Recognition, Automated; Principal Component Analysis; Rats; Rats, Wistar; Toxins, Biological; Xenobiotics

2005
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
    Clinical chemistry, 2005, Volume: 51, Issue:10

    Topics: 1-Naphthylisothiocyanate; Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertrophy; Liver Diseases; Male; Methylcellulose; Organ Size; Phenobarbital; Proteomics; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

2005
In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid.
    Journal of medicinal food, 2005,Fall, Volume: 8, Issue:3

    Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Asteraceae; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlorogenic Acid; Ethionine; Fatty Liver; Galactosamine; gamma-Glutamyltransferase; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Lipids; Liver; Liver Diseases; Male; Plant Leaves; Rats; Rats, Sprague-Dawley

2005
Chemometric analysis of biofluids following toxicant induced hepatotoxicity: a metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:8

    Topics: 1-Naphthylamine; 1-Naphthylisothiocyanate; Animals; Blood Chemical Analysis; Body Fluids; Chemical and Drug Induced Liver Injury; Isocyanates; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Organ Specificity; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Urine

2005
Influence of D-galactosamine and alpha-naphthylisothiocyanate on the activities of some intestinal enzymes.
    Hepato-gastroenterology, 1984, Volume: 31, Issue:5

    Topics: 1-Naphthylisothiocyanate; 5'-Nucleotidase; Alanine Transaminase; Alkaline Phosphatase; alpha-Glucosidases; Animals; Aspartate Aminotransferases; beta-Galactosidase; Bilirubin; Galactosamine; gamma-Glutamyltransferase; Intestinal Mucosa; Jejunum; Liver Diseases; Male; Nucleotidases; Rats; Rats, Inbred Strains; Sucrase; Thiocyanates

1984
[Effects of cianidanol (KB-53) on experimental liver injury in mice--histopathological, histochemical and enzyme-histochemical studies].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:6

    Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Benzopyrans; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver Injury; Flavonoids; Glucose-6-Phosphatase; Histocytochemistry; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR

1983
Therapeutic properties of dihydroxy-dibutylether on sub-acute liver damage induced by several hepatotoxic agents in rats.
    International journal of tissue reactions, 1982, Volume: 4, Issue:4

    Topics: 1-Naphthylisothiocyanate; 1-Propanol; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethers; Ethionine; Female; Liver Diseases; Male; Propanols; Rats; Rats, Inbred Strains

1982
[Protective effects of the stem of Berchemia racemosa Sieb. et Zucc. on experimental liver injuries].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1995, Volume: 115, Issue:4

    Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis; Drugs, Chinese Herbal; Liver Diseases; Male; Plant Stems; Rats; Rats, Wistar

1995
Leukotrienes and alpha-naphthylisothiocyanate-induced liver injury.
    Toxicology, 1995, Jun-26, Volume: 100, Issue:1-3

    Topics: 1-Naphthylisothiocyanate; Acetamides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Hydroxyurea; Indoles; Inflammation; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Liver; Liver Diseases; Male; Phenyl Ethers; Rats; Rats, Sprague-Dawley

1995
[Protective effects of Taiwan crude drugs on experimental liver injuries].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1993, Volume: 113, Issue:12

    Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholestasis; Drugs, Chinese Herbal; Liver Diseases; Male; Methanol; Rats; Rats, Wistar; Water

1993
A microcholangiographic study of liver disease models in rats.
    Academic radiology, 1995, Volume: 2, Issue:6

    Topics: 1-Naphthylisothiocyanate; Animals; Bile Duct Diseases; Bile Ducts; Carbon Tetrachloride; Cell Division; Cholangiography; Contrast Media; Disease Models, Animal; Female; Ligation; Lipopolysaccharides; Liver Diseases; Peptidoglycan; Rats; Rats, Inbred Lew

1995
Effect of pretreatment of rats with an urinary preparation on liver injuries induced by carbon tetrachloride and alpha-naphthylisothiocyanate.
    The American journal of Chinese medicine, 1998, Volume: 26, Issue:3-4

    Topics: 1-Naphthylisothiocyanate; Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholangitis; Glutathione; Humans; Hyperbilirubinemia; Lipid Peroxidation; Liver; Liver Diseases; Male; Rats; Rats, Wistar; Urine

1998
A kinetic model of mitochondrial aspartate aminotransferase transmigration in hepatobiliary disorders.
    Annals of clinical biochemistry, 1999, Volume: 36 ( Pt 2)

    Topics: 1-Naphthylisothiocyanate; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholestasis; Computer Simulation; Indocyanine Green; Isoenzymes; Kinetics; Liver Diseases; Male; Mitochondria; Models, Biological; Rats; Rats, Wistar; Time Factors

1999
The evaluation of the therapeutic effect of tao-shang-tsao on alpha-naphthylisothiocyanate and carbon tetrachloride-induced acute liver damage in rats.
    The American journal of Chinese medicine, 2000, Volume: 28, Issue:3-4

    Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Cholangitis; Drugs, Chinese Herbal; Hyperbilirubinemia; Liver; Liver Diseases; Male; Plant Extracts; Rats; Rats, Wistar

2000
Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data.
    The Analyst, 2002, Volume: 127, Issue:2

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Data Interpretation, Statistical; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Xenobiotics

2002
Phospholipids in endoplasmic reticulum - their relationship to drug metabolism in experimental liver disease.
    Acta hepato-gastroenterologica, 1977, Volume: 24, Issue:5

    Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis; Choline Deficiency; Endoplasmic Reticulum; Galactosamine; Hepatitis; Liver Diseases; Phospholipids; Rats

1977
[Protective effects of the fractions extracted from the callus of Acer nikoense Maxim. on alpha-naphthylisothiocyanate induced liver injury].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992, Volume: 112, Issue:2

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Liver Diseases; Male; Plant Extracts; Rats; Rats, Inbred Strains; Trees

1992
The differential effects of hepatotoxicants on the sulfation pathway in rats.
    Toxicology and applied pharmacology, 1991, Sep-15, Volume: 110, Issue:3

    Topics: 1-Naphthylisothiocyanate; 1-Propanol; Aflatoxin B1; Alanine Transaminase; Animals; Arylsulfotransferase; Bromobenzenes; Cadmium; Cadmium Chloride; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytosol; Dichloroethylenes; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Phosphoadenosine Phosphosulfate; Propanols; Rats; Rats, Inbred Strains; Sulfates; Thioacetamide

1991
Influence of liver damage on antipyrine metabolite formation in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:5

    Topics: 1-Naphthylisothiocyanate; Animals; Antipyrine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Galactosamine; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains

1991
The effect of liver dysfunction on colchicine pharmacokinetics in the rat.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:2

    Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis; Cimetidine; Colchicine; Cytochrome P-450 Enzyme Inhibitors; Galactosamine; Liver Diseases; Rats; Rats, Inbred Strains

1990
Suppression of delayed-type hypersensitivity mediated by macrophage-like cells in mice with experimental liver injury.
    Immunology, 1985, Volume: 54, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver Injury; Dinoprostone; Drug Hypersensitivity; Hypersensitivity, Delayed; Indomethacin; Liver Diseases; Macrophages; Male; Mice; Mice, Inbred BALB C; Picryl Chloride; Prostaglandins E; Spleen; Superoxides; T-Lymphocytes, Regulatory

1985