1-naphthylacetylspermine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, JH; Yin, HZ | 1 |
| Tang, DT; Weiss, JH; Yin, HZ | 1 |
2 other study(ies) available for 1-naphthylacetylspermine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Marked synergism between mutant SOD1 and glutamate transport inhibition in the induction of motor neuronal degeneration in spinal cord slice cultures.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biological Transport, Active; Cell Survival; Drug Synergism; Enzyme Inhibitors; Male; Motor Neurons; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Culture Techniques; Polymerase Chain Reaction; Rats; Rats, Transgenic; Receptors, AMPA; Spermine; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Vesicular Glutamate Transport Proteins | 2012 |
Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Astrocytes; Disease Models, Animal; Drug Administration Routes; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Male; Motor Neurons; Rats; Spermine; Superoxide Dismutase | 2007 |