1-methyl-4-piperidyl acetate has been researched along with Alzheimer Disease in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietlein, M; Dillen, K; Dronse, J; Fink, GR; Jacobs, HIL; Kracht, L; Kukolja, J; Langen, KJ; Nellessen, N; Neumaier, B; Onur, OA; Richter, N | 1 |
| Beckers, N; Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Fukushi, K; Higuchi, M; Hirano, S; Irie, T; Kuwabara, S; Ota, T; Sato, K; Shimada, H; Shinotoh, H; Suhara, T; Tanaka, N; Zhang, MR | 1 |
| Cappa, SF; Florea, I; Garibotto, V; Marcone, A; Moresco, R; Panzacchi, A; Perani, D; Rinne, J; Tettamanti, M; Virta, JR | 1 |
| Dietlein, M; Fink, GR; Kracht, L; Kukolja, J; Michel, A; Neumaier, B; Onur, OA; Richter, N; Tittgemeyer, M | 1 |
| Järvenpää, T; Kaasinen, V; Kurki, T; Någren, K; Oikonen, V; Rinne, JO; Roivainen, A; Yu, M | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kalbe, E; Lenz, O; Schröder, H; Weisenbach, S; Zündorf, G | 1 |
| Aotsuka, A; Arai, H; Fukushi, K; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Ota, T; Sato, K; Shinotoh, H; Shiraishi, T; Tanada, S; Tanaka, N | 1 |
| Fukushi, K; Ikota, N; Irie, T; Iyo, M; Nagatsuka, S; Namba, H; Tamagami, H | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka , S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Lenz, O; Lercher, M; Wienhard, K | 1 |
| Bauer, B; Heiss, WD; Herholz, K; Kracht, L; Lenz, MO; Mielke, R; Strotmann, T; Wienhard, K | 1 |
| Aotsuka, A; Fukushi, K; Irie, T; Iyo, M; Nagatsuka Si, S; Namba, H; Ota, T; Shinotoh, H; Tanada, S; Tanaka, N | 1 |
4 trial(s) available for 1-methyl-4-piperidyl acetate and Alzheimer Disease
| Article | Year |
|---|---|
Brain acetylcholinesterase activity in mild cognitive impairment and early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Analysis of Variance; Brain; Carbon Radioisotopes; Cognition Disorders; Female; Hippocampus; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Neuropsychological Tests; Piperidines; Predictive Value of Tests; Reference Values; Tomography, Emission-Computed | 2003 |
A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbon Radioisotopes; Cerebral Cortex; Female; Humans; Image Interpretation, Computer-Assisted; Iofetamine; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2004 |
Positron emission tomographic measurement of brain acetylcholinesterase activity using N-[(11)C]methylpiperidin-4-yl acetate without arterial blood sampling: methodology of shape analysis and its diagnostic power for Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Arteries; Blood Specimen Collection; Brain; Carbon Radioisotopes; Humans; Middle Aged; Monte Carlo Method; Piperidines; Tomography, Emission-Computed | 2001 |
Kinetic analysis of [(11)C]MP4A using a high-radioactivity brain region that represents an integrated input function for measurement of cerebral acetylcholinesterase activity without arterial blood sampling.
Topics: Acetates; Acetylcholinesterase; Adult; Aged; Alzheimer Disease; Blood Specimen Collection; Brain; Carbon Radioisotopes; Computer Simulation; Humans; Kinetics; Least-Squares Analysis; Middle Aged; Models, Biological; Piperidines; Tomography, Emission-Computed | 2001 |
9 other study(ies) available for 1-methyl-4-piperidyl acetate and Alzheimer Disease
| Article | Year |
|---|---|
Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2019 |
Effect of cholinergic treatment depends on cholinergic integrity in early Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cerebral Cortex; Cholinergic Agents; Cognitive Dysfunction; Female; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Oxygen; Piperidines; Positron-Emission Tomography; Rivastigmine | 2018 |
Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer's Disease.
Topics: Acetates; Acetylcholinesterase; Age of Onset; Aged; Aging; Alzheimer Disease; Brain; Brain Mapping; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals | 2018 |
Cholinergic activity correlates with reserve proxies in Alzheimer's disease.
Topics: Acetates; Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Carbon Isotopes; Cognitive Dysfunction; Cognitive Reserve; Educational Status; Employment; Female; Fluorodeoxyglucose F18; Humans; Male; Mental Status Schedule; Middle Aged; Piperidines; Positron-Emission Tomography; Radiography; Statistics, Nonparametric; Tomography Scanners, X-Ray Computed | 2013 |
White matter lesions and the cholinergic deficit in aging and mild cognitive impairment.
Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognitive Dysfunction; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Piperidines; Positron-Emission Tomography; White Matter | 2017 |
In vivo study of acetylcholine esterase in basal forebrain, amygdala, and cortex in mild to moderate Alzheimer disease.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Amygdala; Basal Nucleus of Meynert; Blood Glucose; Carbon Radioisotopes; Cerebral Cortex; Cholinergic Fibers; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Piperidines; Tomography, Emission-Computed | 2004 |
Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease.
Topics: Acetates; Acetylcholinesterase; Alzheimer Disease; Amphetamines; Animals; Brain; Carbon Radioisotopes; Iodine Radioisotopes; Iofetamine; Male; Piperidines; Propionates; Rats; Rats, Wistar; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
PET measurement of cerebral acetylcholine esterase activity without blood sampling.
Topics: Acetates; Acetylcholinesterase; Aged; Algorithms; Alzheimer Disease; Basal Ganglia; Brain; Female; Humans; Lewy Body Disease; Male; Middle Aged; Piperidines; Radiopharmaceuticals; Tomography, Emission-Computed | 2001 |
In-vivo measurements of regional acetylcholine esterase activity in degenerative dementia: comparison with blood flow and glucose metabolism.
Topics: Acetates; Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Brain Stem; Carbon Radioisotopes; Cerebellum; Cerebrovascular Circulation; Corpus Striatum; Female; Glucose; Humans; Lewy Body Disease; Male; Mental Status Schedule; Middle Aged; Piperidines; Reference Values; Regression Analysis; Thalamus; Tomography, Emission-Computed | 2000 |