1-methyl-4-phenylpyridinium has been researched along with Innate Inflammatory Response in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 8 (42.11) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, X; Tao, H; Wu, X; Yao, S; Zhang, C | 1 |
| Bae, JE; Cho, DH; Jo, DS; Jung, YK; Kim, JB; Kim, P; Kim, SH; Kim, YH; Lee, HJ; Lee, HS; Lee, WH; Park, NY; Ryoo, ZY; Ryu, HY; Son, M | 1 |
| Fu, S; Gao, X; He, D; He, Y; Li, J; Li, Z; Liu, D; Liu, Y; Wang, H; Ye, B | 1 |
| Huang, YH; Lin, TK; Yang, YL | 1 |
| Hu, Q; Qi, W; Xiong, X; Zeng, D | 1 |
| Chang, KH; Chen, CM; Chen, YC; Chiu, YJ; Lee-Chen, GJ; Lin, CH; Lin, CY; Lo, YS; Wu, YR; Yang, PN; Yao, CF | 1 |
| Amiry-Moghaddam, M; Ottersen, OP; Prydz, A; Skare, Ø; Skauli, N; Stahl, K; Zahl, S | 1 |
| Tian, J; Wang, H; Xu, F; Xu, H | 1 |
| Chen, L; Chen, Z; Gao, X; Xu, J; Yang, C | 1 |
| Choi, MS; Jeon, MT; Jung, UJ; Kim, SR | 1 |
| Lai, TH; Lin, YL; Shiao, YJ; Tsay, HJ; Tzeng, TT | 1 |
| Chen, Z; Liao, J; Liu, X; Wang, Q; Wang, R; Wang, Y; Weng, R; Xia, Y; Zhou, P; Zou, J | 1 |
| Borrajo, A; Diaz-Ruiz, C; Garrido-Gil, P; Labandeira-Garcia, JL; Rodriguez-Perez, AI | 1 |
| Brundin, P; Colca, JR; Escobar Galvis, ML; George, S; Ghosh, A; Hildebrandt, EN; Kordower, JH; Machiela, E; Madaj, Z; McDonald, WG; Schulz, E; Steiner, JA; Tyson, T; Van Raamsdonk, JM | 1 |
| El-Benna, J; Flood, PM; Hong, JS; Hu, X; Qian, L; Wei, SJ; Wilson, B; Xu, Z; Zhang, D | 1 |
| Bournival, J; Martinoli, MG; Plouffe, M; Provencher, C; Renaud, J | 1 |
| An, L; Hong, JS; Li, G; Liu, B; Liu, Y; Qin, L; Zhang, W | 1 |
| Hong, JS; Liu, B; Wang, T; Wilson, B; Zhang, W | 1 |
| Goralski, KB; Renton, KW | 1 |
19 other study(ies) available for 1-methyl-4-phenylpyridinium and Innate Inflammatory Response
| Article | Year |
|---|---|
LINC00943 acts as miR-338-3p sponge to promote MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Line, Tumor; Inflammation; Mice; MicroRNAs; Parkinson Disease; RNA, Long Noncoding; Sp1 Transcription Factor | 2022 |
Carnitine Protects against MPP
Topics: 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Apoptosis; Carnitine; Cell Line, Tumor; Dopaminergic Neurons; Humans; Inflammation; Neuroblastoma; Neurotoxicity Syndromes | 2022 |
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Inflammation; Inflammation Mediators; Iodides; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; NF-E2-Related Factor 2; NF-kappa B; Parkinson Disease; Proto-Oncogene Proteins c-akt; Pyrrolidines; Sesquiterpenes | 2022 |
MiR-29a inhibits MPP + - Induced cell death and inflammation in Parkinson's disease model in vitro by potential targeting of MAVS.
Topics: 1-Methyl-4-phenylpyridinium; 3' Untranslated Regions; Antiviral Agents; Apoptosis; Caspase 3; Cell Death; Cell Line, Tumor; Humans; Inflammation; Interleukin-6; MicroRNAs; Neuroblastoma; Parkinson Disease; Poly(ADP-ribose) Polymerase Inhibitors; Reactive Oxygen Species; Superoxide Dismutase | 2022 |
Knockdown of SEMA7A alleviates MPP
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antigens, CD; Apoptosis; Inflammation; Mice; Microglia; Mitogen-Activated Protein Kinases; PPAR gamma; Semaphorins | 2023 |
Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases; Neurotoxins; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Parkinson Disease; Tumor Necrosis Factor-alpha | 2023 |
Pro-Inflammatory Role of AQP4 in Mice Subjected to Intrastriatal Injections of the Parkinsonogenic Toxin MPP.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Aquaporin 4; Astrocytes; Dopaminergic Neurons; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Injections; Male; Mesencephalon; Mice, Inbred C57BL; Neuroglia; Parkinson Disease; RNA, Messenger; Substantia Nigra | 2020 |
Down-Regulation of ID2-AS1 Alleviates the Neuronal Injury Induced by 1-Methy1-4-Phenylpyridinium in Human Neuroblastoma Cell Line SH-SY5Y Cells Through Regulating miR-199a-5p/IFNAR1/JAK2/STAT1 Axis.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Knockdown Techniques; Humans; Inflammation; Janus Kinase 2; MicroRNAs; Oxidative Stress; Parkinson Disease; Receptor, Interferon alpha-beta; RNA, Long Noncoding; Signal Transduction; STAT1 Transcription Factor; Up-Regulation | 2021 |
Resolvin D1 Attenuates Mpp+-Induced Parkinson Disease via Inhibiting Inflammation in PC12 Cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Disease Models, Animal; Docosahexaenoic Acids; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Inflammation; Interleukin-6; MAP Kinase Kinase 4; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; PC12 Cells; Phosphorylation; Rats; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Silibinin attenuates MPP⁺-induced neurotoxicity in the substantia nigra in vivo.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-1beta; Microglia; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Substantia Nigra; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2014 |
Lithospermic acid attenuates 1-methyl-4-phenylpyridine-induced neurotoxicity by blocking neuronal apoptotic and neuroinflammatory pathways.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents; Apoptosis; Benzofurans; Cell Line; Depsides; Inflammation; Male; Mice; Mice, Inbred ICR; Neurogenesis; Neurons | 2015 |
TLR4 Signaling in MPP⁺-Induced Activation of BV-2 Cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Line; Cell Survival; In Vitro Techniques; Inflammation; Interleukin-1beta; Mice; Microglia; NF-kappa B; Nitric Oxide Synthase Type II; Parkinson Disease; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging.
Topics: 1-Methyl-4-phenylpyridinium; Age Factors; Aging; Angiotensin II; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inflammation; Injections, Intraventricular; Insulin-Like Growth Factor I; Microglia; Neurodegenerative Diseases; Oxidative Stress; Primary Cell Culture; Rats; Receptor, Angiotensin, Type 1; Receptor, IGF Type 1; Renin-Angiotensin System; Substantia Nigra | 2016 |
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Autophagy; Behavior, Animal; Brain; Caenorhabditis elegans; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Heterozygote; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neurodegenerative Diseases; Neurons; Oxygen Consumption; Parkinson Disease; Pyridines; Pyruvic Acid; Signal Transduction; Substantia Nigra; Thiazolidinediones | 2016 |
Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Membrane; Cytoprotection; Cytosol; Dopamine; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Mice; Mice, Knockout; Microglia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 2; NADPH Oxidases; Phosphoserine; Protein Subunits; Protein Transport; Rats; Reactive Oxygen Species; Tissue Culture Techniques; Transforming Growth Factor beta1 | 2008 |
Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Coculture Techniques; Cytokines; Cytoprotection; Dioxoles; Dopaminergic Neurons; Gene Expression Regulation; Inflammation; Kinetics; Lignans; Mice; Microglia; Mitochondria; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; PC12 Cells; Quercetin; Rats; RNA, Messenger; Superoxides | 2012 |
Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.
Topics: 1-Methyl-4-phenylpyridinium; Amyloid beta-Peptides; Animals; Cells, Cultured; Dextromethorphan; Drug Interactions; Inflammation; Lipopolysaccharides; Microglia; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Inbred F344; Receptors, Dopamine; Superoxides; Xanthine; Xanthine Oxidase | 2003 |
Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Cyclooxygenase 2; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Inflammation; Isoenzymes; Lipopolysaccharides; Male; Mesencephalon; Microglia; Nerve Degeneration; Neuroglia; Neurons; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344 | 2004 |
Brain inflammation enhances 1-methyl-4-phenylpyridinium-evoked neurotoxicity in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Cytochrome P-450 Enzyme System; Dopamine Agents; Inflammation; Kidney; Lipopolysaccharides; Liver; Lung; Male; Rats; Rats, Sprague-Dawley | 2004 |