1-methyl-4-phenylpyridinium has been researched along with Degenerative Diseases, Central Nervous System in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 12 (52.17) | 2.80 |
| Authors | Studies |
|---|---|
| Li, DW; Qi, XD; Sun, WP; Zhang, CH | 1 |
| Kang, Y; Liu, S; Wang, L; Wang, Y; Xu, X; Zhang, Y | 1 |
| Çinar, R; Naziroğlu, M; Yildizhan, K | 1 |
| Fu, S; Gao, X; He, D; He, Y; Li, J; Li, Z; Liu, D; Liu, Y; Wang, H; Ye, B | 1 |
| Li, J; Song, L; Sun, Z | 1 |
| Gao, Y; Gao, Z; Han, G; Jiang, Z; Li, F; Wang, M; Wang, Y; Wang, Z; Yin, X | 1 |
| Ashok Kumar, K; Chang, YM; Chiu, PL; Ho, TJ; Hsieh, DJ; Huang, CY; Ju, DT; Kuo, WW; Lee, TK; Liao, PH; Liao, SC | 1 |
| Chen, J; Gong, R; Huang, K; Jia, C; Li, X; Liang, W; Liu, W; Wei, W; Zhang, F; Zhang, J | 1 |
| Cheung, KH; Chun-Kit Tong, B; Gopalkrishnashetty Sreenivasmurthy, S; Iyaswamy, A; Li, M; Liu, J; Lu, J; Malampati, S; Song, J; Su, C; Wang, Z; Yang, C; Zhu, Z | 1 |
| Chiaino, E; Davey, GP; Fernandez-Abascal, J; Frosini, M; Valoti, M | 1 |
| Aiyaz, M; Gayathri, N; Harsha, PK; Jamshidi, N; Padmanabhan, B; Ranganayaki, S; Rashmi, SK; Srinivas Bharath, MM | 1 |
| Ekpo, O; Enogieru, AB; Haylett, W; Hiss, D | 1 |
| Cao, BB; Chen, JN; Gu, TT; Huang, Y; Liu, Z; Peng, YP; Qiu, AW; Qiu, YH; Yang, Y | 1 |
| Borrajo, A; Diaz-Ruiz, C; Garrido-Gil, P; Labandeira-Garcia, JL; Rodriguez-Perez, AI | 1 |
| Brundin, P; Colca, JR; Escobar Galvis, ML; George, S; Ghosh, A; Hildebrandt, EN; Kordower, JH; Machiela, E; Madaj, Z; McDonald, WG; Schulz, E; Steiner, JA; Tyson, T; Van Raamsdonk, JM | 1 |
| Chen, H; Ding, JH; Hu, G; Wang, S | 1 |
| Chan, KC; Mong, MC; Yin, MC | 1 |
| Luchtman, DW; Meng, Q; Shao, D; Song, C; Wang, X | 1 |
| Banerjee, R; Mohanakumar, KP; Sairam, K; Saravanan, KS | 1 |
| Kotake, Y; Ohta, S | 1 |
| Bähr, M; Kilic, E; Kilic, U; Lingor, P; Yulug, B | 1 |
| Allegrini, PR; Arendt, T; Bartsch, D; Berns, H; Goemans, C; Hengerer, B; Heumann, R; Kamdem, RH; Lingenhöhl, K; Narz, F; Obst-Pernberg, K; Schellander, K; Wagner, EF; Wahle, P; Waldmeier, PC | 1 |
| Abramova, NA; Bennett, JP; Cassarino, DS; Khan, SM; Painter, TW | 1 |
1 review(s) available for 1-methyl-4-phenylpyridinium and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
MPP+ analogs acting on mitochondria and inducing neuro-degeneration.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Electron Transport; Humans; Isoquinolines; Mitochondria; Neurodegenerative Diseases; Neurons; Parkinson Disease, Secondary; Rotenone; Ubiquinone; Uncoupling Agents | 2003 |
22 other study(ies) available for 1-methyl-4-phenylpyridinium and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Annexin A2 degradation contributes to dopaminergic cell apoptosis via regulating p53 in neurodegenerative conditions.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Annexin A2; Apoptosis; Cell Survival; Dopaminergic Neurons; Down-Regulation; Neurodegenerative Diseases; PC12 Cells; Rats; Tumor Suppressor Protein p53 | 2021 |
LncRNA MIAT Inhibits MPP
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Proliferation; Gene Expression Regulation; Herbicides; MicroRNAs; Neurodegenerative Diseases; Parkinson Disease; PC12 Cells; Protective Agents; Rats; RNA, Long Noncoding; Sirtuin 1 | 2021 |
The involvement of TRPM2 on the MPP
Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Apoptosis; Hippocampus; Mice; Neurodegenerative Diseases; Neurons; Oxidative Stress; Reactive Oxygen Species; Resveratrol; TRPM Cation Channels | 2022 |
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Inflammation; Inflammation Mediators; Iodides; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; NF-E2-Related Factor 2; NF-kappa B; Parkinson Disease; Proto-Oncogene Proteins c-akt; Pyrrolidines; Sesquiterpenes | 2022 |
LncRNA SNHG15 mediates 1-methyl-4-phenylpyridinium (MPP
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Line, Tumor; MicroRNAs; Neurodegenerative Diseases; Parkinson Disease; RNA, Long Noncoding | 2023 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; Animals; Cytokines; Ketone Bodies; Mice; Neurodegenerative Diseases; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Pyroptosis | 2022 |
Garcinol protects SH-SY5Y cells against MPP+-induced cell death by activating DJ-1/SIRT1 and PGC-1α mediated antioxidant pathway in sequential stimulation of p-AMPK mediated autophagy.
Topics: 1-Methyl-4-phenylpyridinium; AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Autophagy; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Neuroblastoma; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Sirtuin 1 | 2023 |
Integrated insight into the molecular mechanisms of selenium-modulated, MPP
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Humans; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Selenium | 2023 |
A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity
Topics: 1-Methyl-4-phenylpyridinium; Active Transport, Cell Nucleus; alpha-Synuclein; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line, Tumor; Cell Survival; Curcumin; HeLa Cells; Humans; Lysosomes; Neurodegenerative Diseases; Neurons; Parkinson Disease; PC12 Cells; Rats; RNA Interference; Signal Transduction | 2020 |
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; beta-Naphthoflavone; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Ethanol; Humans; Kinetics; Membrane Potential, Mitochondrial; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Protein Isoforms; Reactive Oxygen Species; Xenobiotics | 2020 |
Inhibition of mitochondrial complex II in neuronal cells triggers unique pathways culminating in autophagy with implications for neurodegeneration.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Autophagy; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Electron Transport Complex I; Electron Transport Complex II; Gene Expression; Gene Expression Profiling; Mitochondria; Movement Disorders; Neurodegenerative Diseases; Neurons; Neuroprotection; Neurotoxins; Nitro Compounds; Propionates; Rats; Transcriptome | 2021 |
Inhibition of γH2AX, COX-2 and regulation of antioxidant enzymes in MPP
Topics: 1-Methyl-4-phenylpyridinium; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Dopaminergic Neurons; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Reactive Oxygen Species; Rutin | 2021 |
IL-17A exacerbates neuroinflammation and neurodegeneration by activating microglia in rodent models of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Death; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurodegenerative Diseases; Neuroimmunomodulation; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Th17 Cells; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2019 |
Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging.
Topics: 1-Methyl-4-phenylpyridinium; Age Factors; Aging; Angiotensin II; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inflammation; Injections, Intraventricular; Insulin-Like Growth Factor I; Microglia; Neurodegenerative Diseases; Oxidative Stress; Primary Cell Culture; Rats; Receptor, Angiotensin, Type 1; Receptor, IGF Type 1; Renin-Angiotensin System; Substantia Nigra | 2016 |
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Autophagy; Behavior, Animal; Brain; Caenorhabditis elegans; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Heterozygote; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neurodegenerative Diseases; Neurons; Oxygen Consumption; Parkinson Disease; Pyridines; Pyruvic Acid; Signal Transduction; Substantia Nigra; Thiazolidinediones | 2016 |
Edaravone protects against MPP+ -induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Antipyrine; Apoptosis; Astrocytes; Brain; Cells, Cultured; Cytoprotection; Edaravone; Energy Metabolism; Free Radical Scavengers; Mitochondria; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2008 |
Antioxidative and anti-inflammatory neuroprotective effects of astaxanthin and canthaxanthin in nerve growth factor differentiated PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents; Antioxidants; Canthaxanthin; Caspase 3; Cell Membrane; Cell Survival; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Nerve Growth Factor; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Sodium-Potassium-Exchanging ATPase; Xanthophylls | 2009 |
ω-3 fatty acid eicosapentaenoic acid attenuates MPP+-induced neurodegeneration in fully differentiated human SH-SY5Y and primary mesencephalic cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Humans; Mesencephalon; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Striatum; Diclofenac; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Mortality; Neurodegenerative Diseases; Neuroprotective Agents; Pyrazoles; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sodium Salicylate; Sulfonamides | 2003 |
Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Count; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neurons; Optic Nerve Injuries; Rats; Rats, Wistar; Retinal Ganglion Cells; Rifampin; Tyrosine 3-Monooxygenase | 2004 |
Transgenic activation of Ras in neurons promotes hypertrophy and protects from lesion-induced degeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Axotomy; Brain; Cell Count; Cell Size; Cells, Cultured; Choline O-Acetyltransferase; Enzyme Activation; Hypertrophy; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Motor Neurons; Mutation; Neurodegenerative Diseases; Neuropeptide Y; Neuroprotective Agents; Oxidopamine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Signal Transduction; Substantia Nigra; Tyrosine 3-Monooxygenase | 2000 |
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma.
Topics: 1-Methyl-4-phenylpyridinium; Alzheimer Disease; Amyloid beta-Peptides; Anti-Bacterial Agents; Aristolochic Acids; Benzothiazoles; Bongkrekic Acid; Brain; Caspase Inhibitors; Caspases; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Neuroblastoma; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptide Fragments; Phenanthrenes; Pramipexole; Thiazoles; Tumor Cells, Cultured | 2002 |