1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Necrosis in 4 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iannielli, A | 1 |
| Bido, S | 1 |
| Folladori, L | 1 |
| Segnali, A | 1 |
| Cancellieri, C | 1 |
| Maresca, A | 1 |
| Massimino, L | 1 |
| Rubio, A | 1 |
| Morabito, G | 1 |
| Caporali, L | 1 |
| Tagliavini, F | 1 |
| Musumeci, O | 1 |
| Gregato, G | 1 |
| Bezard, E | 1 |
| Carelli, V | 1 |
| Tiranti, V | 1 |
| Broccoli, V | 1 |
| Yu, C | 1 |
| Kim, BS | 1 |
| Kim, E | 1 |
| Guarnieri, T | 1 |
| Virgili, M | 1 |
| Carraro, S | 1 |
| Villani, L | 1 |
| Tatton, NA | 1 |
| Kish, SJ | 1 |
4 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Necrosis
| Article | Year |
|---|---|
Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Cell Differentiation; Disease Mode | 2018 |
FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adaptor Proteins, Signal Transducing; Animals; Apoptos | 2016 |
Quinolinic acid but not MK-801 protects the dopaminergic system from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced toxicity in goldfish retina.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Chromatography, | 1994 |
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acridine Orange; Animals; Apoptosis; Cats; Cell Nucleu | 1997 |