1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Malignant Melanoma in 3 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammasome involvement in Parkinson's disease (PD) has been intensively investigated." | 1.72 | Microglial AIM2 alleviates antiviral-related neuro-inflammation in mouse models of Parkinson's disease. ( Fan, Y; Hu, YC; Li, S; Liu, Y; Ma, CM; Rui, WJ; Shi, JP; Wang, BW; Yang, L, 2022) |
| "Melanoma is strongly tied to red hair/fair skin, a phenotype of loss-of-function polymorphisms in the MC1R (melanocortin 1 receptor) gene." | 1.46 | The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival. ( Cai, W; Chen, H; Chen, X; Fisher, DE; Li, H; Logan, R; Maguire, M; Robinson, K; Schwarzschild, MA; Vanderburg, CR; Wang, Y; Ya, B; Yu, Y; Zuo, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rui, WJ | 1 |
| Li, S | 1 |
| Yang, L | 1 |
| Liu, Y | 1 |
| Fan, Y | 1 |
| Hu, YC | 1 |
| Ma, CM | 1 |
| Wang, BW | 1 |
| Shi, JP | 1 |
| Chen, X | 1 |
| Chen, H | 1 |
| Cai, W | 1 |
| Maguire, M | 1 |
| Ya, B | 1 |
| Zuo, F | 1 |
| Logan, R | 1 |
| Li, H | 1 |
| Robinson, K | 1 |
| Vanderburg, CR | 1 |
| Yu, Y | 1 |
| Wang, Y | 1 |
| Fisher, DE | 1 |
| Schwarzschild, MA | 1 |
| Umemura, T | 1 |
| Naoi, M | 1 |
| Takahashi, T | 1 |
| Fukui, Y | 1 |
| Yasue, T | 1 |
| Ohashi, M | 1 |
| Nagatsu, T | 1 |
3 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Malignant Melanoma
| Article | Year |
|---|---|
Microglial AIM2 alleviates antiviral-related neuro-inflammation in mouse models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiviral Agents; Disease Models, Animal; DNA | 2022 |
The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Disease Models, Animal; Dop | 2017 |
Cytotoxic effect of 1-methyl-4-phenylpyridinium ion on human melanoma cell lines, HMV-II and SK-MEL-44, is dependent on the melanin contents and caused by inhibition of mitochondrial electron transport.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Cell Line; Cell Survival; Colony-Forming Units Assay; | 1990 |