1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Depressive Disorder in 11 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex." | 1.33 | Activities of prolyl endopeptidase and dipeptidyl peptidase IV in brain structures of rats with dopamine deficiency-dependent MPTP-induced depressive syndrome. ( Bogdanova, NG; Khlebnikova, NN; Krupina, NA; Kryzhanovskii, GN; Orlova, IN; Zolotov, NN, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khlebnikova, NN | 5 |
| Krupina, NA | 11 |
| Bogdanova, NG | 4 |
| Orlova, IN | 9 |
| Zolotov, NN | 4 |
| Kryzhanovskii, GN | 9 |
| Grafova, VN | 1 |
| Smirnova, VS | 1 |
| Kukushkin, ML | 1 |
| Pankova, NB | 1 |
| Rodina, VI | 1 |
| Iordanskaia, TE | 2 |
| Davydova, TV | 1 |
| Fomina, VG | 1 |
1 review available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Depressive Disorder
| Article | Year |
|---|---|
[Insufficiency of nigrostriatal dopaminergic system as a disregulation mechanism of dopamine-dependent depression syndrome].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Depressive Disorder; Disease | 2003 |
10 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Depressive Disorder
| Article | Year |
|---|---|
Effect of prolyl endopeptidase inhibitor benzyloxycarbonyl-methionyl-2(S)-cyanopyrrolidine on the course of experimental depressive syndrome in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Behavior, Animal; Body Weight; Depre | 2013 |
Effect of prolyl endopeptidase inhibitor benzyloxycarbonyl-methionyl-2(S)-cyanopyrrolidine on activity of proline-specific peptidases in brain structures of rats with experimental MPTP-induced depressive syndrome.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents; Behavior, Animal; Corp | 2013 |
Effect of a prolyl endopeptidase inhibitor benzyloxycarbonyl-alanyl-proline on the development of experimental depressive syndrome in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Body Weight; Depressive Dis | 2009 |
Experimental depressive-pain syndrome in rats with initial various anxiety-phobic levels: a behavioral study.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Denervation; Depressive Disorder; Do | 2002 |
Activities of prolyl endopeptidase and dipeptidyl peptidase IV in brain structures of rats with dopamine deficiency-dependent MPTP-induced depressive syndrome.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cerebral Cortex; Depressive Disorder; | 2006 |
[Effect of melipramine on the development of an experimental depressive syndrome in rats, caused by systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents, Tricyclic; Behavior, A | 1995 |
[The effect of parlodel on development of depressive syndrome in rats, caused by administering 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Bromocriptine; Depressive D | 1995 |
[Effect of parlodel on sleep-wakefulness cycle parameters in rats with experimental MPTP-induced depressive syndrome].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Bromocriptine; Depressive Disorder; Dopamine | 1999 |
[Effect of parlodel on the electrical activity of the rat brain during experimental depressive syndrome].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents; Brain; Bromocriptine; | 2000 |
Count and phagocytic activity of leukocytes in rats with experimental depressive syndrome caused by systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Depressive Disorder; Dopamine Agents; Leukocy | 2000 |