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1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Deficiency, Folic Acid

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Deficiency, Folic Acid in 2 studies

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.

Research Excerpts

ExcerptRelevanceReference
"Although the cause of Parkinson's disease (PD) is unknown, data suggest roles for environmental factors that may sensitize dopaminergic neurons to age-related dysfunction and death."1.31Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. ( Cadet, JL; Cutler, RG; Duan, W; Kruman, II; Ladenheim, B; Mattson, MP, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, JW1
Duan, W1
Ladenheim, B1
Cutler, RG1
Kruman, II1
Cadet, JL1
Mattson, MP1

Reviews

1 review available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Deficiency, Folic Acid

ArticleYear
Homocysteine, folate deficiency, and Parkinson's disease.
    Nutrition reviews, 2002, Volume: 60, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Folic Acid Deficiency; Homocysteine

2002

Other Studies

1 other study available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Deficiency, Folic Acid

ArticleYear
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.
    Journal of neurochemistry, 2002, Volume: 80, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biomarkers; Brain; Cell Survival; Corpus Stri

2002