1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Curling Ulcer in 9 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Curling Ulcer: Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cysteamine is the first chemical identified that induces acute and chronic duodenal ulcers in rodents." | 8.77 | From cysteamine to MPTP: structure-activity studies with duodenal ulcerogens. ( Cho, CH; Szabo, S, 1988) |
| "Cysteamine is the first chemical identified that induces acute and chronic duodenal ulcers in rodents." | 4.77 | From cysteamine to MPTP: structure-activity studies with duodenal ulcerogens. ( Cho, CH; Szabo, S, 1988) |
| "The effect of the duodenal ulcerogen cysteamine on gastric emptying of a liquid meal was compared to that of two newly identified duodenal ulcerogens, MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and mepirizole." | 3.67 | Biphasic effect of duodenal ulcerogens on gastric emptying in the rat. ( Kline, TJ; Pihan, G; Szabo, S, 1988) |
| " The degree of reduction was correlated with time and dosage of MPTP administered." | 1.29 | [Monoamine concentrations in experimental ulcers in rats]. ( Deng, X; Gen, Q; Zheng, Z, 1996) |
| "Duodenal ulcers were produced in rats by 12 subcutaneous injections of a neurotoxin, MPTP, over 4 days." | 1.28 | MPTP-induced duodenal ulcers in rat. Prevention by reuptake blockers for serotonin and norepinephrine, but not dopamine. ( Fields, JZ; Gordon, JH; Keshavarzian, A; Wibowo, A, 1990) |
| "Duodenal ulcers were prevented by pretreatment with dopamine agonists (e." | 1.27 | Evidence for the involvement of dopamine agonists and antagonists in duodenal ulcer disease. ( Neumeyer, JL; Szabo, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, XY | 1 |
| Zheng, ZT | 1 |
| Deng, X | 1 |
| Gen, Q | 1 |
| Zheng, Z | 1 |
| Keshavarzian, A | 2 |
| Haydek, JM | 1 |
| Zepeda, DO | 1 |
| Stinneford, JG | 1 |
| Fields, JZ | 2 |
| Wibowo, A | 1 |
| Gordon, JH | 1 |
| Szabo, S | 5 |
| Brown, A | 1 |
| Pihan, G | 3 |
| Dali, H | 1 |
| Neumeyer, JL | 2 |
| Mangla, JC | 1 |
| Brown, HA | 1 |
| Rattan, S | 1 |
| Cho, CH | 1 |
| Kline, TJ | 1 |
1 review available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Curling Ulcer
| Article | Year |
|---|---|
From cysteamine to MPTP: structure-activity studies with duodenal ulcerogens.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cysteamine; Duodenal Ulcer; Pyridines; Rodent | 1988 |
8 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Curling Ulcer
| Article | Year |
|---|---|
[An animal model of peptic ulcer induced by destruction of dopaminergic neurons].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Drug Administration R | 1994 |
[Monoamine concentrations in experimental ulcers in rats].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biogenic Amines; Dopamine; Duodenal Ulcer; In | 1996 |
Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alprostadil; Animals; Atropine; Duodenal Ulcer; Female | 1990 |
MPTP-induced duodenal ulcers in rat. Prevention by reuptake blockers for serotonin and norepinephrine, but not dopamine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine Antagonists; Dose-Response Relations | 1990 |
Duodenal ulcer induced by MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amylases; Animals; Bicarbonates; Bromocriptine; Dose-R | 1985 |
Effect of duodenal ulcerogens cysteamine, mepirizole, and MPTP on duodenal myoelectric activity in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cysteamine; Duodenal Ulcer; Duodenum; Epirizo | 1989 |
Biphasic effect of duodenal ulcerogens on gastric emptying in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chronic Disease; Cysteamine; Drug Administrat | 1988 |
Evidence for the involvement of dopamine agonists and antagonists in duodenal ulcer disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; | 1986 |