1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Colitis in 1 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Then, in mouse models, we assessed whether dextran sodium sulfate-mediated colitis could exert lingering effects on dopaminergic pathways in the brain and whether colitis increased vulnerability to a subsequent exposure to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)." | 4.02 | Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. ( Caudle, WM; Chang, J; Houser, MC; Joers, V; Kannarkat, GT; Kelly, SD; Keshavarzian, A; Oliver, D; Shannon, KM; Tansey, MG; Yang, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houser, MC | 1 |
| Caudle, WM | 1 |
| Chang, J | 1 |
| Kannarkat, GT | 1 |
| Yang, Y | 1 |
| Kelly, SD | 1 |
| Oliver, D | 1 |
| Joers, V | 1 |
| Shannon, KM | 1 |
| Keshavarzian, A | 1 |
| Tansey, MG | 1 |
1 other study available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Colitis
| Article | Year |
|---|---|
Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; CD8 Antigens; CD8-Positive T-Lymphocyt | 2021 |