1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Chorea Disorders in 4 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves for chorea and dystonia revealed that the same dose of L-dopa (30 mg/kg) induced the highest score for both dyskinesias: however, the severity was much greater for chorea." | 1.28 | Characterisation of dyskinesias induced by L-dopa in MPTP-treated squirrel monkeys. ( Boyce, S; Iversen, SD; Rupniak, NM; Steventon, MJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomez-Ramirez, J | 1 |
| Johnston, TH | 1 |
| Visanji, NP | 1 |
| Fox, SH | 1 |
| Brotchie, JM | 1 |
| Papa, SM | 1 |
| Chase, TN | 1 |
| Rupniak, NM | 2 |
| Boyce, S | 2 |
| Steventon, MJ | 2 |
| Iversen, SD | 2 |
4 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Chorea Disorders
| Article | Year |
|---|---|
Histamine H3 receptor agonists reduce L-dopa-induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Callithrix; Chorea; Disease Models, Animal; F | 2006 |
Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Chore | 1996 |
(+)-PHNO: a new anti-parkinsonian agent which does not induce chorea in MPTP-treated squirrel monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Cutaneous; Animals; Antiparkinson Agen | 1990 |
Characterisation of dyskinesias induced by L-dopa in MPTP-treated squirrel monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chorea; Dose-Response Relationship, Drug; Dys | 1990 |