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1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Carotid Stenosis

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Carotid Stenosis in 1 studies

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to investigate the effect of chronic cerebral hypoperfusion (CCH) on cognitive dysfunction, structural abnormalities of the hippocampus and white matter (WM), and levels of inflammatory cytokines in control and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse models."3.91Hippocampal damage and white matter lesions contribute to cognitive impairment in MPTP-lesioned mice with chronic cerebral hypoperfusion. ( Feng, S; Gao, L; Gao, Y; Huang, Z; Nie, K; Tang, H; Wang, L; Zhang, Y; Zhao, J; Zhu, R, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, Y1
Tang, H1
Nie, K1
Zhu, R1
Gao, L1
Feng, S1
Wang, L2
Zhao, J1
Huang, Z1
Zhang, Y1

Other Studies

1 other study available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Carotid Stenosis

ArticleYear
Hippocampal damage and white matter lesions contribute to cognitive impairment in MPTP-lesioned mice with chronic cerebral hypoperfusion.
    Behavioural brain research, 2019, 08-05, Volume: 368

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Brain; Brain Ischemia; Carotid Ste

2019