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1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Age-Related Memory Disorders

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Age-Related Memory Disorders in 12 studies

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, TT1
Kim, KS1
Shin, KS1
Park, HJ1
Kim, HJ1
Lee, KE1
Lee, MK1
Zhu, G1
Li, J1
He, L2
Wang, X1
Hong, X1
Rajput, SK1
Sharma, AK1
Meena, CL1
Pant, AB1
Jain, R1
Sharma, SS1
Kakefuda, K1
Fujita, Y1
Oyagi, A1
Hyakkoku, K1
Kojima, T1
Umemura, K1
Tsuruma, K1
Shimazawa, M1
Ito, M1
Nozawa, Y1
Hara, H1
Monaghan, MM1
Leddy, L1
Sung, ML1
Albinson, K1
Kubek, K1
Pangalos, MN1
Reinhart, PH1
Zaleska, MM1
Comery, TA1
Hsieh, MH1
Gu, SL1
Ho, SC1
Pawlak, CR1
Lin, CL1
Ho, YJ1
Lai, TJ1
Wu, FY1
Castro, AA1
Ghisoni, K1
Latini, A1
Quevedo, J1
Tasca, CI1
Prediger, RD1
Da Cunha, C4
Wietzikoski, S1
Wietzikoski, EC1
Miyoshi, E2
Ferro, MM1
Anselmo-Franci, JA1
Canteras, NS3
Yang, J1
Wang, J1
Adams, JD1
Braga, R1
Kouzmine, I1
Gevaerd, MS2
Takahashi, RN2
Silveira, R2

Other Studies

12 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Age-Related Memory Disorders

ArticleYear
Gypenosides ameliorate memory deficits in MPTP-lesioned mouse model of Parkinson's disease treated with L-DOPA.
    BMC complementary and alternative medicine, 2017, Sep-06, Volume: 17, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain Chemistry; Disease Mo

2017
MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway.
    British journal of pharmacology, 2015, Volume: 172, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Ag

2015
Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Catalepsy; Cell Death; Diseas

2016
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection.
    Biochemical and biophysical research communications, 2009, Oct-02, Volume: 387, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Memory Disorders; Mice; Mice,

2009
Social odor recognition: a novel behavioral model for cognitive dysfunction in Parkinson's disease.
    Neuro-degenerative diseases, 2010, Volume: 7, Issue:1-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Disease Models, Animal;

2010
Effects of MK-801 on recognition and neurodegeneration in an MPTP-induced Parkinson's rat model.
    Behavioural brain research, 2012, Apr-01, Volume: 229, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Brain; Disease Models,

2012
Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.
    Behavioural brain research, 2012, Apr-01, Volume: 229, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Intranasal; Age Factors; Animals; Anim

2012
Evidence for the substantia nigra pars compacta as an essential component of a memory system independent of the hippocampal memory system.
    Neurobiology of learning and memory, 2003, Volume: 79, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine Agents; Male; Maze

2003
Early administration of nicotinamide prevents learning and memory impairment in mice induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Learning; Male; Memory Disorders; Mice; Niaci

2004
Lesion of the substantia nigra, pars compacta impairs delayed alternation in a Y-maze in rats.
    Experimental neurology, 2005, Volume: 192, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition Disorders; Denervation; Disease Mod

2005
Caffeine reverses the memory disruption induced by intra-nigral MPTP-injection in rats.
    Brain research bulletin, 2001, May-01, Volume: 55, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Avoidance Learning; Caffeine; Central Nervous

2001
L-Dopa restores striatal dopamine level but fails to reverse MPTP-induced memory deficits in rats.
    The international journal of neuropsychopharmacology, 2001, Volume: 4, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Avoidance Learning; Ben

2001