1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Acute Confusional Senile Dementia in 14 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common chronic neurodegenerative disorders, characterized by motoric dysfunction or cognitive decline in the early stage, respectively, but often by both symptoms in the advanced stage." | 2.66 | Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease. ( Barilar, JO; Homolak, J; Knezovic, A; Perhoc, AB; Riederer, P; Salkovic-Petrisic, M, 2020) |
| "The hypothesis is that Alzheimer's disease, Parkinson's disease (PD), and motoneurone disease are due to environmental damage to specific regions of the central nervous system and that the damage remains subclinical for several decades but makes those affected especially prone to the consequences of age-related neuronal attrition." | 1.27 | Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment? ( Calne, DB; Eisen, A; McGeer, E; Spencer, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bandaru, LJM | 1 |
| Ayyalasomayajula, N | 1 |
| Murumulla, L | 1 |
| Dixit, PK | 1 |
| Challa, S | 1 |
| Barilar, JO | 1 |
| Knezovic, A | 1 |
| Perhoc, AB | 1 |
| Homolak, J | 1 |
| Riederer, P | 1 |
| Salkovic-Petrisic, M | 1 |
| Gratuze, M | 1 |
| Josset, N | 1 |
| Petry, FR | 1 |
| Pflieger, M | 1 |
| Eyoum Jong, L | 1 |
| Truchetti, G | 1 |
| Poitras, I | 1 |
| Julien, J | 1 |
| Bezeau, F | 1 |
| Morin, F | 1 |
| Samadi, P | 1 |
| Cicchetti, F | 1 |
| Bretzner, F | 1 |
| Planel, E | 1 |
| Mundiñano, IC | 1 |
| Hernandez, M | 1 |
| Dicaudo, C | 1 |
| Ordoñez, C | 1 |
| Marcilla, I | 1 |
| Tuñon, MT | 1 |
| Luquin, MR | 1 |
| Minematsu, M | 1 |
| Nakajima, K | 1 |
| Cole, GM | 1 |
| Vila, M | 1 |
| Przedborski, S | 1 |
| Asanuma, M | 1 |
| Miyazaki, I | 1 |
| Tsuji, T | 1 |
| Ogawa, N | 1 |
| Plate, R | 1 |
| Plaum, MJ | 1 |
| de Boer, T | 1 |
| Andrews, JS | 1 |
| Rae, DR | 1 |
| Gibson, S | 1 |
| Beal, MF | 1 |
| Taylor, R | 1 |
| Calne, DB | 1 |
| Eisen, A | 1 |
| McGeer, E | 1 |
| Spencer, P | 1 |
| Hirai, S | 1 |
| Battistin, L | 1 |
| Rigo, A | 1 |
| Bracco, F | 1 |
| Dam, M | 1 |
| Pizzolato, G | 1 |
4 reviews available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Disease Models, Animal; Do | 2020 |
Targeting programmed cell death in neurodegenerative diseases.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anim | 2003 |
[New aspects of neuroprotective effects of nonsteroidal anti-inflammatory drugs].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflamm | 2003 |
Metabolic disorders and neurotoxicology.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Humans; Metabolic Diseases; Nerve D | 1995 |
10 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Defective mitophagy and induction of apoptosis by the depleted levels of PINK1 and Parkin in Pb and β-amyloid peptide induced toxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; H | 2022 |
The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Alzheimer Disease; Animals; Brain; Co | 2019 |
Reduced cholinergic olfactory centrifugal inputs in patients with neurodegenerative disorders and MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; C | 2013 |
Significant effect of dimethylsulfoniopropionate on Parkinson's disease of senescence-accelerated mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Alzheimer Disea | 2008 |
Ironic fate: can a banned drug control metal heavies in neurodegenerative diseases?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Clioquinol; Ferritins; Gen | 2003 |
Synthesis and muscarinic activities of 3-(pyrazolyl)-1,2,5,6-tetrahydropyridine derivatives.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Analysis of Variance; Animals; Bind | 1996 |
A lot of "excitement' about neurodegeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Alzheimer Disease; Animals; Dizocilpine Maleate | 1991 |
Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aging; Alzheimer Disease; Animals; Environmenta | 1986 |
[Biochemistry of the physiopathologic and clinical aspects of free radicals in cerebral degenerative diseases such as Alzheimer's and Parkinson diseases].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Catecholamines; Free Radic | 1988 |
Metabolic aspects of aging brain and related disorders.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Alzheimer Disease; Animals; Brain; Cerebral Cor | 1987 |